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SPRI_5016 SPRI_5016 rplW rplW rplD rplD nusA nusA rplA rplA rplJ rplJ rpsL rpsL rpsG rpsG rlmN rlmN SPRI_2261 SPRI_2261 ffh ffh rnc rnc gltX gltX mnmA mnmA SPRI_2528 SPRI_2528 SPRI_1818 SPRI_1818 SPRI_1689 SPRI_1689 rsgA rsgA SPRI_1534 SPRI_1534 nfi nfi rplC rplC SPRI_1009 SPRI_1009 SPRI_0763 SPRI_0763 SPRI_0762 SPRI_0762 SPRI_0647 SPRI_0647 rnj rnj rpmE rpmE rho rho SPRI_2768 SPRI_2768 SPRI_2775 SPRI_2775 SPRI_3084 SPRI_3084 rpsI rpsI rplM rplM truA truA rpsK rpsK rpsM rpsM SPRI_6897 SPRI_6897 SPRI_6885 SPRI_6885 SPRI_6844 SPRI_6844 SPRI_6795 SPRI_6795 SPRI_6402 SPRI_6402 SPRI_6176 SPRI_6176 SPRI_6096 SPRI_6096 nusB nusB alaS alaS rpsD rpsD SPRI_6054 SPRI_6054 thrS thrS SPRI_6012 SPRI_6012 pheT pheT pheS pheS SPRI_5954 SPRI_5954 rplT rplT SPRI_5870 SPRI_5870 SPRI_5845 SPRI_5845 SPRI_5757 SPRI_5757 SPRI_5742 SPRI_5742 tyrS tyrS SPRI_5517 SPRI_5517 SPRI_5502 SPRI_5502 SPRI_5431 SPRI_5431 ileS ileS SPRI_5214 SPRI_5214 rnhB rnhB era era rpsT rpsT proB proB rplU rplU SPRI_4919 SPRI_4919 SPRI_4668 SPRI_4668 rph rph smpB smpB SPRI_4438 SPRI_4438 rplY rplY rsmA rsmA SPRI_4077 SPRI_4077 dtd dtd serS serS rplI rplI rpsR-2 rpsR-2 rpsF rpsF SPRI_3800 SPRI_3800 SPRI_3788 SPRI_3788 SPRI_3753 SPRI_3753 SPRI_3739 SPRI_3739 SPRI_3726 SPRI_3726 SPRI_3678 SPRI_3678 rpsN rpsN rpsR rpsR lysS lysS SPRI_3310 SPRI_3310 rplK rplK rpsJ rpsJ rnj-2 rnj-2 pnp pnp rpsO rpsO SPRI_2182 SPRI_2182 truB truB infA infA rplO rplO rpsE rpsE rplR rplR rplF rplF rpsH rpsH rpsZ rpsZ rplE rplE rplX rplX rplN rplN rpsQ rpsQ rplP rplP rpsC rpsC rplV rplV rpsS rpsS rplB rplB
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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SPRI_5016tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (383 aa)
rplW50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (107 aa)
rplD50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. (216 aa)
nusATranscription termination factor NusA; Participates in both transcription termination and antitermination. (331 aa)
rplA50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (242 aa)
rplJ50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (176 aa)
rpsL30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (123 aa)
rpsG30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
rlmN23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (368 aa)
SPRI_2261KH domain RNA binding protein YlqC; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the UPF0109 family. (79 aa)
ffhSignal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (517 aa)
rncRibonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (296 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (491 aa)
mnmAtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (375 aa)
SPRI_2528Translation factor SUA5; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the SUA5 family. (215 aa)
SPRI_1818Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (905 aa)
SPRI_1689Peptide-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (252 aa)
rsgAGTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (372 aa)
SPRI_1534Putative lipoprotein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (242 aa)
nfiEndonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. (231 aa)
rplC50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (214 aa)
SPRI_1009rRNA methylase SpoU; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (190 aa)
SPRI_0763Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (268 aa)
SPRI_0762Lipoprotein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (173 aa)
SPRI_0647Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (400 aa)
rnjRibonuclease; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (561 aa)
rpmE50S ribosomal protein L31; Binds the 23S rRNA. (74 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (692 aa)
SPRI_2768GTP-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (635 aa)
SPRI_2775Fibrillarin; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (694 aa)
SPRI_3084VWA domain-containing protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (391 aa)
rpsI30S ribosomal protein S9; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS9 family. (172 aa)
rplM50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (147 aa)
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (289 aa)
rpsK30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (134 aa)
rpsM30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (126 aa)
SPRI_6897Plasmid stabilization protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (107 aa)
SPRI_6885Transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (230 aa)
SPRI_6844Translation factor Sua5; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the SUA5 family. (206 aa)
SPRI_6795Lipoprotein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (172 aa)
SPRI_6402B3/4 domain protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (230 aa)
SPRI_6176FHA domain-containing protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (179 aa)
SPRI_6096rRNA cytosine-C5-methyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (477 aa)
nusBTranscription antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (142 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (889 aa)
rpsD30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (204 aa)
SPRI_6054DNA repair ATPase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (409 aa)
thrSthreonyl-tRNA synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (657 aa)
SPRI_6012rRNA methyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (272 aa)
pheTphenylalanyl-tRNA synthetase subunit beta; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (842 aa)
pheSphenylalanyl-tRNA synthetase subunit alpha; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (373 aa)
SPRI_5954RNA methyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (283 aa)
rplT50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (127 aa)
SPRI_5870Pseudouridylate synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (314 aa)
SPRI_58452'-5' RNA ligase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (357 aa)
SPRI_5757Pseudouridine synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (368 aa)
SPRI_5742Cytochrome C oxidase subunit II; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (271 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (422 aa)
SPRI_5517Transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (218 aa)
SPRI_5502Ribonuclease; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (130 aa)
SPRI_5431Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (313 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1046 aa)
SPRI_5214Ribonuclease II; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (479 aa)
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (233 aa)
eraGTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (313 aa)
rpsT30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. (88 aa)
proBGamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (368 aa)
rplU50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (106 aa)
SPRI_4919Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (1465 aa)
SPRI_4668Von Willebrand factor type A; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (71 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (244 aa)
smpBSingle-stranded DNA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome t [...] (159 aa)
SPRI_4438Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (246 aa)
rplY50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (198 aa)
rsmADimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (286 aa)
SPRI_4077RNA methyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (317 aa)
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (145 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (425 aa)
rplI50S ribosomal protein L9; Binds to the 23S rRNA. (148 aa)
rpsR-230S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (78 aa)
rpsF30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (96 aa)
SPRI_3800RNA nucleotidyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (488 aa)
SPRI_3788Single-stranded DNA-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (170 aa)
SPRI_3753Nosiheptide resistance regulatory protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (225 aa)
SPRI_3739FHA domain protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (170 aa)
SPRI_3726rRNA methyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (219 aa)
SPRI_3678RNA-binding protein S4; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (134 aa)
rpsN30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa)
rpsR30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (82 aa)
lysSlysyl-tRNA synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (574 aa)
SPRI_3310Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (129 aa)
rplK50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (144 aa)
rpsJ30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
rnj-2Ribonuclease; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (561 aa)
pnpPolynucleotide phosphorylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (738 aa)
rpsO30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (96 aa)
SPRI_2182threonyl-tRNA synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (408 aa)
truBtRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (299 aa)
infATranslation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (73 aa)
rplO50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (151 aa)
rpsE30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (201 aa)
rplR50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (127 aa)
rplF50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (179 aa)
rpsH30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa)
rpsZ30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. (61 aa)
rplE50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (185 aa)
rplX50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (107 aa)
rplN50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa)
rpsQ30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (94 aa)
rplP50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (139 aa)
rpsC30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (276 aa)
rplV50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (123 aa)
rpsS30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (93 aa)
rplB50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (278 aa)
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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