STRINGSTRING
SPRI_1676 SPRI_1676 SPRI_0154 SPRI_0154 c101_05c c101_05c cpp29 cpp29 cpp27 cpp27 cpp14 cpp14 SPRI_0376 SPRI_0376 SPRI_0788 SPRI_0788 SPRI_1091 SPRI_1091 SPRI_1163 SPRI_1163 SPRI_1765 SPRI_1765 SPRI_1882 SPRI_1882 SPRI_1885 SPRI_1885 SPRI_1886 SPRI_1886 SPRI_1887 SPRI_1887 SPRI_2001 SPRI_2001 SPRI_2009 SPRI_2009 SPRI_2441 SPRI_2441 glgE glgE glgB glgB SPRI_2575 SPRI_2575 SPRI_2622 SPRI_2622 SPRI_2702 SPRI_2702 SPRI_2830 SPRI_2830 SPRI_2888 SPRI_2888 SPRI_2893 SPRI_2893 SPRI_2910 SPRI_2910 SPRI_2911 SPRI_2911 SPRI_2960 SPRI_2960 SPRI_2983 SPRI_2983 SPRI_3401 SPRI_3401 SPRI_3427 SPRI_3427 SPRI_3545 SPRI_3545 SPRI_3547 SPRI_3547 SPRI_3548 SPRI_3548 pyrE pyrE SPRI_3618 SPRI_3618 SPRI_3741 SPRI_3741 SPRI_3805 SPRI_3805 SPRI_3806 SPRI_3806 kptA kptA SPRI_3898 SPRI_3898 upp upp purF purF mshA mshA SPRI_4105 SPRI_4105 SPRI_4107 SPRI_4107 SPRI_4354 SPRI_4354 SPRI_4392 SPRI_4392 SPRI_4442 SPRI_4442 SPRI_4546 SPRI_4546 SPRI_4562 SPRI_4562 SPRI_4633 SPRI_4633 SPRI_4654 SPRI_4654 SPRI_4682 SPRI_4682 SPRI_4864 SPRI_4864 SPRI_4912 SPRI_4912 SPRI_4926 SPRI_4926 SPRI_4929 SPRI_4929 SPRI_4935 SPRI_4935 SPRI_5181 SPRI_5181 cobT cobT trpD trpD SPRI_5366 SPRI_5366 SPRI_5367 SPRI_5367 SPRI_5419 SPRI_5419 murG murG SPRI_5423 SPRI_5423 hisH hisH hisF hisF lgt lgt SPRI_5720 SPRI_5720 SPRI_5745 SPRI_5745 SPRI_5776 SPRI_5776 SPRI_5777 SPRI_5777 SPRI_5993 SPRI_5993 cobT-2 cobT-2 SPRI_6038 SPRI_6038 apt apt mltG mltG pyrR pyrR hisG hisG SPRI_6135 SPRI_6135 SPRI_6147 SPRI_6147 SPRI_6148 SPRI_6148 mltG-2 mltG-2 SPRI_6363 SPRI_6363 SPRI_6368 SPRI_6368 SPRI_6532 SPRI_6532 SPRI_6859 SPRI_6859 SPRI_6860 SPRI_6860 SPRI_6870 SPRI_6870 SPRI_6916 SPRI_6916 SPRI_7085 SPRI_7085 SPRI_7098 SPRI_7098 SPRI_7100 SPRI_7100 SPRI_7125 SPRI_7125 SPRI_7199 SPRI_7199
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPRI_1676Glycosyl transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the UDP-glycosyltransferase family. (400 aa)
SPRI_0154Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (348 aa)
c101_05cPutative anthranilate phosphoribosyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (346 aa)
cpp29Glycosyl transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (412 aa)
cpp27Putative C-glycosyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (377 aa)
cpp14Glycosyl transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (417 aa)
SPRI_0376Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (325 aa)
SPRI_0788Integral membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (319 aa)
SPRI_1091Glycosyl hydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (228 aa)
SPRI_1163Uncharacterized protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (463 aa)
SPRI_1765Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (296 aa)
SPRI_1882Glycosyl transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (352 aa)
SPRI_1885Glycosyl transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (420 aa)
SPRI_1886Glycosyl transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (321 aa)
SPRI_1887Glycosyl transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (344 aa)
SPRI_2001Glycosyl transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (426 aa)
SPRI_2009Glycosyl transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (414 aa)
SPRI_2441Alpha-glucan phosphorylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (913 aa)
glgEAlpha-1,4-glucan:maltose-1-phosphate maltosyltransferase; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. (665 aa)
glgBGlycogen branching protein; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (1018 aa)
SPRI_2575Cell division protein FtsW; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the SEDS family. (463 aa)
SPRI_2622Integral membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (519 aa)
SPRI_2702Transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (556 aa)
SPRI_2830Penicillin-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (744 aa)
SPRI_2888Glycosyl transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (385 aa)
SPRI_2893Glycosyl transferase family 1; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (382 aa)
SPRI_2910Dolichol-phosphate mannosyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (402 aa)
SPRI_2911Glycosyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (558 aa)
SPRI_2960Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (272 aa)
SPRI_2983Pyrimidine-nucleoside phosphorylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (425 aa)
SPRI_3401Nicotinate-nucleotide pyrophosphorylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. (334 aa)
SPRI_3427Hypoxanthine phosphoribosyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (179 aa)
SPRI_3545Penicillin-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (743 aa)
SPRI_3547Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (487 aa)
SPRI_3548Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (407 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (179 aa)
SPRI_3618Phosphoribosyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (165 aa)
SPRI_3741Cell division protein FtsW; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the SEDS family. (471 aa)
SPRI_3805Penicillin-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (895 aa)
SPRI_3806Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (513 aa)
kptAPhosphotransferase KptA/Tpt1; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase. (186 aa)
SPRI_3898Integral membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (698 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (220 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (550 aa)
mshAD-inositol 3-phosphate glycosyltransferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway. (446 aa)
SPRI_4105Alpha,alpha-trehalose-phosphate synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (485 aa)
SPRI_4107Glucosyl-3-phosphoglycerate synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (322 aa)
SPRI_4354Purine nucleoside phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. (298 aa)
SPRI_4392Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (576 aa)
SPRI_4442Glycosyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (329 aa)
SPRI_4546Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (241 aa)
SPRI_4562Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (418 aa)
SPRI_4633Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (442 aa)
SPRI_4654Penicillin-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (878 aa)
SPRI_4682Secreted protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (560 aa)
SPRI_48644-alpha-glucanotransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (729 aa)
SPRI_4912Rod shape-determining protein RodA; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the SEDS family. (400 aa)
SPRI_4926Transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (674 aa)
SPRI_4929Glycosyl transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (418 aa)
SPRI_4935Glycosyl transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (720 aa)
SPRI_5181Glycosyl transferase family 1; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (441 aa)
cobTNicotinate-nucleotide; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (369 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (354 aa)
SPRI_5366Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (413 aa)
SPRI_5367Glycosyl transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (380 aa)
SPRI_5419Cell division protein FtsW; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the SEDS family. (547 aa)
murGUDP-diphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (364 aa)
SPRI_5423Laccase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the multicopper oxidase YfiH/RL5 family. (249 aa)
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (216 aa)
hisFImidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (251 aa)
lgtDiacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (380 aa)
SPRI_5720Queuosine biosynthesis protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (359 aa)
SPRI_5745Glycosyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (361 aa)
SPRI_5776Glycosyl transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (428 aa)
SPRI_5777Transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (274 aa)
SPRI_5993Glycosyl transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (411 aa)
cobT-2Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (1236 aa)
SPRI_6038GDP-mannose-dependent alpha-(1-2)-phosphatidylinositol mannosyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (387 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (180 aa)
mltGMembrane protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (600 aa)
pyrRUracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. (192 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (282 aa)
SPRI_6135Dolichol-phosphate mannosyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (247 aa)
SPRI_6147Glycosyl transferase family 1; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (374 aa)
SPRI_6148Glycosyl transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (389 aa)
mltG-2Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (289 aa)
SPRI_6363Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (295 aa)
SPRI_6368Glycosyl transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (401 aa)
SPRI_6532Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (366 aa)
SPRI_6859Galactosyldiacylglycerol synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (370 aa)
SPRI_6860Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (283 aa)
SPRI_6870Trehalose 6-phosphate phosphorylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (805 aa)
SPRI_6916Multidrug transporter; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (1157 aa)
SPRI_7085Glycosyl transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (417 aa)
SPRI_7098Putative C-glycosyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (377 aa)
SPRI_7100Glycosyl transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (412 aa)
SPRI_7125Putative anthranilate phosphoribosyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (346 aa)
SPRI_7199Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (348 aa)
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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