(26 nodes) Carbohydrate transmembrane transport network (Streptomyces pristinaespiralis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rbsA	Sugar ABC transporter ATPase; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (513 aa)
	SPRI_4642	PTS sugar transporter subunit IIA; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (419 aa)
	SPRI_4643	PTS sugar transporter; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (77 aa)
	SPRI_4685	ABC transporter substrate-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (363 aa)
	SPRI_5897	Glycerol transporter; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the MIP/aquaporin (TC 1.A.8) family. (263 aa)
	SPRI_6160	Glycerol transporter; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the MIP/aquaporin (TC 1.A.8) family. (253 aa)
	SPRI_6169	Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (556 aa)
	SPRI_6170	PTS glucose transporter subunit IIA; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (150 aa)
	rbsA-2	Putative ABC transporter ATP-binding protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (509 aa)
	SPRI_6510	Sugar ABC transporter ATP-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (278 aa)
	SPRI_2063	Phosphocarrier protein HPr; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (93 aa)
	SPRI_1806	ABC transporter substrate-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (370 aa)
	SPRI_1805	ABC transporter ATP-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (262 aa)
	SPRI_1414	Sugar ABC transporter ATP-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (275 aa)
	SPRI_1251	Sugar ABC transporter ATPase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (504 aa)
	SPRI_0568	ABC sugar transporter; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (618 aa)
	SPRI_0073	Porin; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the MIP/aquaporin (TC 1.A.8) family. (276 aa)
	SPRI_6866	Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (571 aa)
	SPRI_7280	Porin; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (276 aa)
	SPRI_3871	Magnesium or manganese-dependent protein phosphatase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (470 aa)
	SPRI_6584	Xylose ABC transporter ATP-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (520 aa)
	SPRI_6585	Sugar ABC transporter substrate-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (367 aa)
	SPRI_6816	PTS fructose transporter subunit IIA; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (136 aa)
	SPRI_6864	PTS lactose transporter subunit IIC; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (673 aa)
	SPRI_6865	Dihydroxyacetone kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (92 aa)
	SPRI_4641	PTS lactose transporter subunit IIC; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (424 aa)

Your Current Organism:

Streptomyces pristinaespiralis

NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SPRI_0073	SPRI_6816	SPRI_0073	SPRI_6816	Porin; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the MIP/aquaporin (TC 1.A.8) family.	PTS fructose transporter subunit IIA; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.446
SPRI_0073	SPRI_6864	SPRI_0073	SPRI_6864	Porin; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the MIP/aquaporin (TC 1.A.8) family.	PTS lactose transporter subunit IIC; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.475
SPRI_0568	SPRI_1806	SPRI_0568	SPRI_1806	ABC sugar transporter; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	ABC transporter substrate-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.557
SPRI_0568	SPRI_4685	SPRI_0568	SPRI_4685	ABC sugar transporter; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	ABC transporter substrate-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.526
SPRI_0568	SPRI_6585	SPRI_0568	SPRI_6585	ABC sugar transporter; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Sugar ABC transporter substrate-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.444
SPRI_0568	SPRI_6864	SPRI_0568	SPRI_6864	ABC sugar transporter; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	PTS lactose transporter subunit IIC; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.438
SPRI_1251	SPRI_1806	SPRI_1251	SPRI_1806	Sugar ABC transporter ATPase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	ABC transporter substrate-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.507
SPRI_1251	SPRI_4685	SPRI_1251	SPRI_4685	Sugar ABC transporter ATPase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	ABC transporter substrate-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.481
SPRI_1251	SPRI_6864	SPRI_1251	SPRI_6864	Sugar ABC transporter ATPase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	PTS lactose transporter subunit IIC; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.438
SPRI_1251	rbsA	SPRI_1251	SPRI_1221	Sugar ABC transporter ATPase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Sugar ABC transporter ATPase; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.	0.905
SPRI_1414	SPRI_1806	SPRI_1414	SPRI_1806	Sugar ABC transporter ATP-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	ABC transporter substrate-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.410
SPRI_1414	SPRI_6864	SPRI_1414	SPRI_6864	Sugar ABC transporter ATP-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	PTS lactose transporter subunit IIC; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.438
SPRI_1805	SPRI_1806	SPRI_1805	SPRI_1806	ABC transporter ATP-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	ABC transporter substrate-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.993
SPRI_1805	SPRI_4685	SPRI_1805	SPRI_4685	ABC transporter ATP-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	ABC transporter substrate-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.955
SPRI_1805	SPRI_6585	SPRI_1805	SPRI_6585	ABC transporter ATP-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Sugar ABC transporter substrate-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.491
SPRI_1805	SPRI_6864	SPRI_1805	SPRI_6864	ABC transporter ATP-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	PTS lactose transporter subunit IIC; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.438
SPRI_1806	SPRI_0568	SPRI_1806	SPRI_0568	ABC transporter substrate-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	ABC sugar transporter; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.557
SPRI_1806	SPRI_1251	SPRI_1806	SPRI_1251	ABC transporter substrate-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Sugar ABC transporter ATPase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.507
SPRI_1806	SPRI_1414	SPRI_1806	SPRI_1414	ABC transporter substrate-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Sugar ABC transporter ATP-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.410
SPRI_1806	SPRI_1805	SPRI_1806	SPRI_1805	ABC transporter substrate-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	ABC transporter ATP-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.993