STRINGSTRING
argS argS trpS-2 trpS-2 panC panC tilS tilS SPRI_3671 SPRI_3671 metG metG SPRI_3879 SPRI_3879 SPRI_3966 SPRI_3966 cysS cysS SPRI_6421 SPRI_6421 SPRI_6407 SPRI_6407 SPRI_6406 SPRI_6406 argG argG mshC mshC SPRI_5759 SPRI_5759 tyrS tyrS ileS ileS nadE nadE leuS leuS nadD nadD valS valS SPRI_4752 SPRI_4752 SPRI_0766 SPRI_0766 SPRI_0741 SPRI_0741 SPRI_0612 SPRI_0612 SPRI_0217 SPRI_0217 c104_15 c104_15 cysD cysD SPRI_1662 SPRI_1662 SPRI_1512 SPRI_1512 SPRI_1169 SPRI_1169 SPRI_1746 SPRI_1746 SPRI_1883 SPRI_1883 SPRI_2004 SPRI_2004 SPRI_2035 SPRI_2035 SPRI_2183 SPRI_2183 coaD coaD gltX gltX mnmA mnmA trpS trpS guaA guaA lysS lysS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
argSarginyl-tRNA synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (587 aa)
trpS-2tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (332 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (348 aa)
tilStRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (347 aa)
SPRI_3671Universal stress protein UspA; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (152 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (525 aa)
SPRI_3879Polycistronic operon; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (200 aa)
SPRI_3966Asparagine synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (716 aa)
cysScysteinyl-tRNA synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (464 aa)
SPRI_6421Deoxyribodipyrimidine photolyase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the DNA photolyase family. (457 aa)
SPRI_6407Electron transfer flavoprotein subunit alpha; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (320 aa)
SPRI_6406Electron transfer flavoprotein subunit beta; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (261 aa)
argGArgininosuccinate synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (397 aa)
mshCL-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. (409 aa)
SPRI_5759Transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (356 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (422 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1046 aa)
nadENAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (585 aa)
leuSleucyl-tRNA synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (950 aa)
nadDNicotinic acid mononucleotide adenyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (211 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (873 aa)
SPRI_4752Universal stress protein UspA; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (173 aa)
SPRI_0766Universal stress protein A; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (180 aa)
SPRI_0741Universal stress protein UspA; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (103 aa)
SPRI_0612Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (285 aa)
SPRI_0217Putative stress protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (152 aa)
c104_15Stress protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (294 aa)
cysDSulfate adenylyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (312 aa)
SPRI_1662Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (233 aa)
SPRI_1512methionyl-tRNA synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (504 aa)
SPRI_1169Asparagine synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (620 aa)
SPRI_1746Indole-3-glycerol phosphate synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (156 aa)
SPRI_1883D-beta-D-heptose 1-phosphate adenosyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (469 aa)
SPRI_2004Asparagine synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (644 aa)
SPRI_2035Histidine kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (847 aa)
SPRI_2183Bifunctional riboflavin kinase/FMN adenylyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (319 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (170 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (491 aa)
mnmAtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (375 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (337 aa)
guaAGMP synthase; Catalyzes the synthesis of GMP from XMP. (531 aa)
lysSlysyl-tRNA synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (574 aa)
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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