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SPRI_0541 SPRI_0541 SPRI_0983 SPRI_0983 idi idi SPRI_1037 SPRI_1037 SPRI_1128 SPRI_1128 dxs dxs ispG ispG dxr dxr SPRI_2495 SPRI_2495 SPRI_2561 SPRI_2561 SPRI_2627 SPRI_2627 ispH ispH SPRI_2843 SPRI_2843 SPRI_3257 SPRI_3257 ispD ispD ispF ispF ispE ispE SPRI_4465 SPRI_4465 SPRI_4998 SPRI_4998 SPRI_5169 SPRI_5169 SPRI_5491 SPRI_5491 SPRI_6961 SPRI_6961
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPRI_0541Polyprenyl synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. (337 aa)
SPRI_0983Polyprenyl diphosphate synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. (361 aa)
idiIsopentenyl-diphosphate delta isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). (197 aa)
SPRI_1037acetyl-CoA acetyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (404 aa)
SPRI_1128acetyl-CoA acetyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (407 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (646 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (419 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (416 aa)
SPRI_2495acetyl-CoA acetyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
SPRI_2561Geranylgeranyl pyrophosphate synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. (359 aa)
SPRI_2627Polyprenyl diphosphate synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. (345 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (306 aa)
SPRI_2843UDP pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (253 aa)
SPRI_3257Geranylgeranyl pyrophosphate synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. (336 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (245 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (167 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (299 aa)
SPRI_4465acetyl-CoA acetyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
SPRI_4998UDP pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (281 aa)
SPRI_5169acetyl-CoA acetyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa)
SPRI_5491acetyl-CoA acetyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (385 aa)
SPRI_6961acetyl-CoA acetyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (388 aa)
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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