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Rcas_0269 | PFAM: regulatory protein TetR; KEGG: rrs:RoseRS_0266 transcriptional regulator, TetR family. (207 aa) | ||||
sigA | RNA polymerase, sigma 70 subunit, RpoD family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (541 aa) | ||||
dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. (652 aa) | ||||
Rcas_0252 | Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; SMART: regulatory protein Crp; KEGG: rrs:RoseRS_0292 putative transcriptional regulator, Crp/Fnr family. (218 aa) | ||||
Rcas_0238 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: rrs:RoseRS_0309 RNA polymerase, sigma-24 subunit, ECF subfamily; Belongs to the sigma-70 factor family. ECF subfamily. (197 aa) | ||||
Rcas_0229 | Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rrs:RoseRS_0612 two component transcriptional regulator, winged helix family. (227 aa) | ||||
Rcas_0211 | Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; Bacterio-opsin activator HTH domain protein; Sigma-70 region 4 type 2; KEGG: rrs:RoseRS_0691 two component transcriptional regulator, LuxR family. (227 aa) | ||||
Rcas_0168 | TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: rrs:RoseRS_4590 DNA protecting protein DprA. (360 aa) | ||||
Rcas_0155 | Multi-sensor signal transduction histidine kinase; PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein; KEGG: rrs:RoseRS_0484 multi-sensor signal transduction histidine kinase. (1014 aa) | ||||
Rcas_0136 | PFAM: transcriptional regulator TrmB; KEGG: rrs:RoseRS_0464 transcriptional regulator, TrmB. (261 aa) | ||||
Rcas_0101 | PFAM: iron dependent repressor; FeoA family protein; KEGG: rrs:RoseRS_4549 iron dependent repressor. (237 aa) | ||||
mutL | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (605 aa) | ||||
Rcas_0068 | KEGG: rrs:RoseRS_4009 hypothetical protein. (464 aa) | ||||
mutS2 | MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (826 aa) | ||||
Rcas_0060 | PFAM: HEAT domain containing protein; transcriptional regulator domain protein; PBS lyase HEAT domain protein repeat-containing protein; transcriptional activator domain; Tetratricopeptide TPR_4; SMART: AAA ATPase; KEGG: rrs:RoseRS_3322 transcriptional activator domain. (1145 aa) | ||||
xerC | Integrase family protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (314 aa) | ||||
Rcas_0044 | PFAM: integrase family protein; KEGG: rrs:RoseRS_0860 phage integrase family protein. (337 aa) | ||||
Rcas_0027 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. (175 aa) | ||||
Rcas_0024 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: rrs:RoseRS_4530 RNA polymerase, sigma-24 subunit, ECF subfamily; Belongs to the sigma-70 factor family. ECF subfamily. (224 aa) | ||||
greA | Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. (157 aa) | ||||
dnaA | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. (480 aa) | ||||
Rcas_0749 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (377 aa) | ||||
Rcas_0802 | PFAM: 4-vinyl reductase 4VR; KEGG: rrs:RoseRS_4449 4-vinyl reductase, 4VR. (215 aa) | ||||
Rcas_0834 | Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rrs:RoseRS_4483 two component transcriptional regulator, winged helix family. (226 aa) | ||||
Rcas_0838 | TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: rrs:RoseRS_0295 transcriptional regulator, BadM/Rrf2 family. (146 aa) | ||||
Rcas_0846 | PFAM: response regulator receiver; KEGG: rrs:RoseRS_0337 response regulator receiver protein. (139 aa) | ||||
smc | Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1200 aa) | ||||
Rcas_0875 | PFAM: DNA methylase N-4/N-6 domain protein; KEGG: rrs:RoseRS_4513 DNA methylase N-4/N-6 domain protein; Belongs to the N(4)/N(6)-methyltransferase family. (281 aa) | ||||
ligA | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (718 aa) | ||||
Rcas_0882 | PFAM: DNA polymerase beta domain protein region; KEGG: gme:Gmet_3257 DNA polymerase, beta-like region. (156 aa) | ||||
Rcas_0907 | Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: cmi:CMM_0295 putative transcriptional regulator, LacI family. (341 aa) | ||||
Rcas_0958 | KEGG: rrs:RoseRS_3691 hypothetical protein. (408 aa) | ||||
Rcas_0960 | Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rrs:RoseRS_3485 two component transcriptional regulator, winged helix family. (236 aa) | ||||
Rcas_0969 | PFAM: regulatory protein TetR; KEGG: rrs:RoseRS_3834 transcriptional regulator, TetR family. (216 aa) | ||||
Rcas_0988 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: rrs:RoseRS_3810 RNA polymerase, sigma-24 subunit, ECF subfamily; Belongs to the sigma-70 factor family. ECF subfamily. (185 aa) | ||||
Rcas_0993 | PFAM: response regulator receiver; KEGG: rrs:RoseRS_3814 response regulator receiver protein. (127 aa) | ||||
lon | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (786 aa) | ||||
Rcas_0997 | Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rrs:RoseRS_3818 two component transcriptional regulator, winged helix family. (230 aa) | ||||
Rcas_1002 | PFAM: NERD domain protein; DNA topoisomerase type IA zn finger domain protein; KEGG: tte:TTE0673 hypothetical protein. (281 aa) | ||||
Rcas_1008 | PFAM: protein of unknown function UPF0150; KEGG: rrs:RoseRS_1435 protein of unknown function UPF0150. (86 aa) | ||||
Rcas_1033 | KEGG: rrs:RoseRS_0405 hypothetical protein. (202 aa) | ||||
Rcas_1040 | Transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; KEGG: aav:Aave_4229 two component transcriptional regulator, LuxR family. (216 aa) | ||||
Rcas_1044 | PFAM: regulatory protein LuxR; KEGG: sye:Syncc9902_1855 transcriptional regulator, LuxR family. (90 aa) | ||||
Rcas_1054 | Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; AraC-type transcriptional regulator domain protein; KEGG: pmy:Pmen_2638 AraC-type transcriptional regulator domain protein. (311 aa) | ||||
lexA | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (218 aa) | ||||
Rcas_1076 | PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: rrs:RoseRS_3807 AAA ATPase, central domain protein. (544 aa) | ||||
Rcas_1080 | PFAM: DNA methylase N-4/N-6 domain protein; KEGG: rrs:RoseRS_0124 site-specific DNA-methyltransferase (adenine-specific). (305 aa) | ||||
mraZ | TIGRFAM: MraZ protein; PFAM: protein of unknown function UPF0040; KEGG: rrs:RoseRS_3777 MraZ protein; Belongs to the MraZ family. (143 aa) | ||||
ruvA | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (197 aa) | ||||
Rcas_1114 | PFAM: response regulator receiver; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: rrs:RoseRS_3770 response regulator receiver protein. (391 aa) | ||||
Rcas_1142 | Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: rrs:RoseRS_3421 two component transcriptional regulator, LuxR family. (222 aa) | ||||
Rcas_1144 | PFAM: protein of unknown function DUF218; KEGG: rrs:RoseRS_3427 protein of unknown function DUF218. (196 aa) | ||||
Rcas_1148 | KEGG: rrs:RoseRS_0396 hypothetical protein. (556 aa) | ||||
Rcas_1168 | Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system. (77 aa) | ||||
Rcas_1171 | PFAM: DNA methylase N-4/N-6 domain protein; KEGG: rrs:RoseRS_4284 DNA methylase N-4/N-6 domain protein; Belongs to the N(4)/N(6)-methyltransferase family. (314 aa) | ||||
Rcas_1176 | Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rrs:RoseRS_0805 two component transcriptional regulator, winged helix family. (229 aa) | ||||
Rcas_1193 | PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: rrs:RoseRS_0820 cell divisionFtsK/SpoIIIE. (806 aa) | ||||
Rcas_1196 | Protein serine phosphatase with GAF(s) sensor(s); PFAM: GAF domain protein; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: rrs:RoseRS_2162 protein serine phosphatase with GAF(s) sensor(s). (1004 aa) | ||||
Rcas_1228 | Transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; KEGG: rrs:RoseRS_0799 response regulator receiver protein. (204 aa) | ||||
Rcas_1272 | PFAM: response regulator receiver; KEGG: rrs:RoseRS_0519 response regulator receiver protein. (322 aa) | ||||
Rcas_1277 | Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: rrs:RoseRS_0524 alanine racemase. (344 aa) | ||||
Rcas_1282 | Transcriptional regulator, XRE family; SMART: helix-turn-helix domain protein; KEGG: rrs:RoseRS_0529 helix-turn-helix domain protein. (279 aa) | ||||
Rcas_1285 | Transcriptional repressor, CopY family; PFAM: Penicillinase repressor; KEGG: rrs:RoseRS_0532 transcriptional repressor, CopY family. (139 aa) | ||||
Rcas_1293 | PFAM: DNA methylase N-4/N-6 domain protein; KEGG: rrs:RoseRS_2183 DNA methylase N-4/N-6 domain protein. (356 aa) | ||||
Rcas_1315 | Hypothetical protein; KEGG: sbl:Sbal_1580 DNA methylase N-4/N-6 domain protein. (273 aa) | ||||
Rcas_1343 | PFAM: protein of unknown function DUF218; KEGG: rrs:RoseRS_4260 protein of unknown function DUF218. (213 aa) | ||||
Rcas_1354 | PFAM: response regulator receiver; KEGG: rrs:RoseRS_4271 response regulator receiver protein. (153 aa) | ||||
Rcas_1355 | Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: rrs:RoseRS_4275 two component transcriptional regulator, LuxR family. (230 aa) | ||||
rex | CoA-binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. (220 aa) | ||||
Rcas_1468 | PFAM: transposase IS200-family protein; KEGG: rrs:RoseRS_0733 transposase IS200-family protein. (137 aa) | ||||
mfd | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1246 aa) | ||||
Rcas_1504 | Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rrs:RoseRS_3737 two component transcriptional regulator, winged helix family. (231 aa) | ||||
polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (972 aa) | ||||
Rcas_1516 | Transcriptional modulator of MazE/toxin, MazF; KEGG: ana:alr0758 hypothetical protein. (125 aa) | ||||
Rcas_1527 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. (152 aa) | ||||
dinG | DNA polymerase III, epsilon subunit; 3'-5' exonuclease. (944 aa) | ||||
Rcas_1579 | PFAM: regulatory protein LuxR; response regulator receiver; KEGG: rrs:RoseRS_0938 two component transcriptional regulator, LuxR family. (242 aa) | ||||
Rcas_1582 | TIGRFAM: bacteriochlorophyll 4-vinyl reductase; PFAM: 4-vinyl reductase 4VR; KEGG: rrs:RoseRS_0940 bacteriochlorophyll 4-vinyl reductase. (201 aa) | ||||
rpoC | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1502 aa) | ||||
rpoB | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1245 aa) | ||||
Rcas_1611 | KEGG: cph:Cpha266_1225 hypothetical protein. (213 aa) | ||||
Rcas_1650 | KEGG: rrs:RoseRS_1294 hypothetical protein. (216 aa) | ||||
Rcas_1660 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: rrs:RoseRS_1304 RNA polymerase, sigma-24 subunit, ECF subfamily; Belongs to the sigma-70 factor family. ECF subfamily. (200 aa) | ||||
topA | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (836 aa) | ||||
Rcas_1691 | TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; KEGG: rrs:RoseRS_1429 helix-hairpin-helix motif. (222 aa) | ||||
Rcas_1708 | PFAM: transposase IS4 family protein; KEGG: rrs:RoseRS_1382 transposase, IS4 family protein. (273 aa) | ||||
Rcas_1745 | PFAM: peptidase S16 lon domain protein; KEGG: rrs:RoseRS_2124 peptidase S16, lon domain protein. (209 aa) | ||||
Rcas_1767 | PFAM: regulatory protein TetR; KEGG: rrs:RoseRS_2103 transcriptional regulator, TetR family. (209 aa) | ||||
Rcas_1779 | Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: rrs:RoseRS_2090 helix-turn-helix-domain containing protein, AraC type. (311 aa) | ||||
Rcas_1782 | PFAM: regulatory protein AsnC/Lrp family; KEGG: rrs:RoseRS_2086 putative transcriptional regulator, AsnC family. (76 aa) | ||||
Rcas_1810 | PFAM: DNA methylase N-4/N-6 domain protein; KEGG: tel:tlr1878 DNA-methyltransferase; Belongs to the N(4)/N(6)-methyltransferase family. (329 aa) | ||||
Rcas_1849 | Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; helix-turn-helix domain protein; periplasmic binding protein/LacI transcriptional regulator; KEGG: rrs:RoseRS_2559 alanine racemase. (358 aa) | ||||
Rcas_1912 | KEGG: dge:Dgeo_2791 transcriptional regulator, LuxR family. (239 aa) | ||||
Rcas_1915 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: sth:STH169 RNA polymerase ECF-type sigma factor. (195 aa) | ||||
Rcas_1916 | Response regulator receiver protein; KEGG: dge:Dgeo_2791 transcriptional regulator, LuxR family. (268 aa) | ||||
Rcas_1925 | Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: rrs:RoseRS_4503 two component transcriptional regulator, LuxR family. (204 aa) | ||||
Rcas_1936 | ATP-dependent transcriptional regulator, MalT-like, LuxR family; PFAM: regulatory protein LuxR; TPR repeat-containing protein; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: rrs:RoseRS_2963 regulatory protein, LuxR. (880 aa) | ||||
Rcas_1939 | PFAM: DNA methylase N-4/N-6 domain protein; KEGG: rrs:RoseRS_0953 DNA methylase N-4/N-6 domain protein; Belongs to the N(4)/N(6)-methyltransferase family. (375 aa) | ||||
cas1 | CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (339 aa) | ||||
Rcas_2010 | PFAM: DNA methylase N-4/N-6 domain protein; KEGG: rrs:RoseRS_0375 DNA methylase N-4/N-6 domain protein; Belongs to the N(4)/N(6)-methyltransferase family. (370 aa) | ||||
radA | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (464 aa) | ||||
Rcas_2025 | TIGRFAM: DNA binding domain, excisionase family; PFAM: regulatory protein MerR; KEGG: rrs:RoseRS_1745 DNA binding domain, excisionase family. (206 aa) | ||||
Rcas_2038 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: rrs:RoseRS_1760 RNA polymerase, sigma-24 subunit, ECF subfamily; Belongs to the sigma-70 factor family. ECF subfamily. (205 aa) | ||||
Rcas_2042 | GAF modulated sigma54 specific transcriptional regulator, Fis family; KEGG: yen:YE0550 glycerol metabolism operon regulatory protein; TIGRFAM: PAS sensor protein; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; PAS fold domain protein; SMART: PAS domain containing protein; AAA ATPase. (674 aa) | ||||
Rcas_2049 | TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: rrs:RoseRS_1771 single-strand binding protein. (138 aa) | ||||
Rcas_2065 | PFAM: alpha/beta hydrolase fold; cyclic nucleotide-binding; KEGG: rrs:RoseRS_1786 cyclic nucleotide-binding protein. (462 aa) | ||||
Rcas_2068 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: rrs:RoseRS_1471 RNA polymerase, sigma-24 subunit, ECF subfamily; Belongs to the sigma-70 factor family. ECF subfamily. (192 aa) | ||||
Rcas_2076 | KEGG: mma:MM3038 transposase; TIGRFAM: transposase, IS605 OrfB family; PFAM: putative transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB. (380 aa) | ||||
Rcas_2120 | Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: aau:AAur_1100 putative transcription regulator, GntR family. (240 aa) | ||||
Rcas_2121 | KEGG: rrs:RoseRS_3491 response regulator receiver and SARP domain protein. (333 aa) | ||||
Rcas_2124 | PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: rrs:RoseRS_3495 cell divisionFtsK/SpoIIIE. (1579 aa) | ||||
lon-2 | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (821 aa) | ||||
Rcas_2179 | PFAM: transcriptional regulator PadR family protein; KEGG: sma:SAV6305 PadR-family transcriptional regulator. (186 aa) | ||||
Rcas_2192 | PFAM: regulatory protein TetR; KEGG: rrs:RoseRS_1070 transcriptional regulator, TetR family. (225 aa) | ||||
recF | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (394 aa) | ||||
Rcas_2226 | KEGG: pmm:PMM0384 possible uncharacterized restriction enzyme, interrupted-C. (837 aa) | ||||
Rcas_2231 | PFAM: DNA methylase N-4/N-6 domain protein; KEGG: sil:SPO3451 modification methylase; Belongs to the N(4)/N(6)-methyltransferase family. (369 aa) | ||||
Rcas_2237 | PFAM: Restriction endonuclease EcoRV; KEGG: hhe:HH0239 type II restriction endonuclease. (226 aa) | ||||
Rcas_2258 | Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; Bacterio-opsin activator HTH domain protein; KEGG: rrs:RoseRS_1633 two component transcriptional regulator, LuxR family. (254 aa) | ||||
recR | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (205 aa) | ||||
Rcas_2292 | Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. (100 aa) | ||||
dnaX | DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (644 aa) | ||||
Rcas_2304 | Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: rrs:RoseRS_1545 GntR domain protein. (224 aa) | ||||
Rcas_2376 | Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: mlo:mlr1331 probable transcriptional regulator. (342 aa) | ||||
Rcas_2412 | PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: rrs:RoseRS_2571 regulatory protein, IclR. (258 aa) | ||||
Rcas_2456 | Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: rrs:RoseRS_2856 periplasmic binding protein/LacI transcriptional regulator. (352 aa) | ||||
Rcas_2467 | KEGG: rrs:RoseRS_2846 Rossmann fold nucleotide-binding protein involved in DNA uptake-like protein. (439 aa) | ||||
Rcas_2487 | Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rrs:RoseRS_2290 two component transcriptional regulator, winged helix family. (224 aa) | ||||
Rcas_2518 | PFAM: DNA methylase N-4/N-6 domain protein; KEGG: rrs:RoseRS_1826 DNA methylase N-4/N-6 domain protein. (464 aa) | ||||
Rcas_2543 | TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: rrs:RoseRS_2821 ParB-like partition protein; Belongs to the ParB family. (358 aa) | ||||
Rcas_2552 | Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: rrs:RoseRS_2816 transcriptional regulator, GntR family. (245 aa) | ||||
lon-3 | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (802 aa) | ||||
Rcas_2569 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: rrs:RoseRS_2791 RNA polymerase, sigma-24 subunit, ECF subfamily; Belongs to the sigma-70 factor family. ECF subfamily. (193 aa) | ||||
Rcas_2571 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: rrs:RoseRS_2793 RNA polymerase, sigma-24 subunit, ECF subfamily; Belongs to the sigma-70 factor family. ECF subfamily. (200 aa) | ||||
Rcas_2599 | Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mta:Moth_1478 two component transcriptional regulator, winged helix family. (232 aa) | ||||
Rcas_2626 | PFAM: ThiJ/PfpI domain protein; KEGG: rrs:RoseRS_1495 ThiJ/PfpI domain protein. (199 aa) | ||||
Rcas_2653 | PFAM: transcriptional activator domain; KEGG: rrs:RoseRS_1512 response regulator receiver and SARP domain protein. (572 aa) | ||||
Rcas_2664 | PFAM: response regulator receiver; KEGG: rrs:RoseRS_3060 response regulator receiver protein. (147 aa) | ||||
cas1-2 | CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (332 aa) | ||||
Rcas_2696 | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rrs:RoseRS_1233 ABC transporter related. (659 aa) | ||||
Rcas_2697 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: rrs:RoseRS_1234 RNA polymerase, sigma-24 subunit, ECF subfamily; Belongs to the sigma-70 factor family. ECF subfamily. (211 aa) | ||||
priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (866 aa) | ||||
Rcas_2728 | KEGG: rrs:RoseRS_4066 hypothetical protein. (157 aa) | ||||
nth | DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (219 aa) | ||||
Rcas_2775 | KEGG: ppd:Ppro_2335 hypothetical protein. (129 aa) | ||||
Rcas_2782 | Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rrs:RoseRS_0114 two component transcriptional regulator, winged helix family. (231 aa) | ||||
Rcas_2795 | Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rrs:RoseRS_1088 two component transcriptional regulator, winged helix family. (266 aa) | ||||
Rcas_2835 | Transcriptional regulator, MerR family; PFAM: regulatory protein MerR; KEGG: rrs:RoseRS_1647 putative transcriptional regulator, MerR family. (97 aa) | ||||
Rcas_2845 | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rrs:RoseRS_2495 ABC transporter related. (559 aa) | ||||
Rcas_2861 | TIGRFAM: transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain protein; KEGG: gur:Gura_1405 transcriptional regulator, AbrB family. (69 aa) | ||||
Rcas_2866 | TIGRFAM: integron integrase; PFAM: integrase family protein; KEGG: tbd:Tbd_1215 integron integrase; Belongs to the 'phage' integrase family. (276 aa) | ||||
Rcas_2867 | KEGG: mhu:Mhun_2566 hypothetical protein. (110 aa) | ||||
Rcas_2869 | KEGG: cph:Cpha266_1139 hypothetical protein. (104 aa) | ||||
Rcas_2885 | Protein of unknown function UPF0150; PFAM: CopG domain protein DNA-binding domain protein; protein of unknown function UPF0150; KEGG: lpf:plpl0034 hypothetical protein. (137 aa) | ||||
Rcas_2887 | RNA polymerase, sigma 70 subunit, RpoD family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (351 aa) | ||||
Rcas_2892 | KEGG: rrs:RoseRS_3164 hypothetical protein. (259 aa) | ||||
Rcas_2921 | KEGG: rrs:RoseRS_3193 hypothetical protein. (368 aa) | ||||
recA | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (353 aa) | ||||
Rcas_2972 | RNA polymerase, sigma 70 subunit, RpoD family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (348 aa) | ||||
uvrC | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (665 aa) | ||||
Rcas_3018 | KEGG: rrs:RoseRS_2041 hypothetical protein. (390 aa) | ||||
Rcas_3019 | KEGG: rrs:RoseRS_2042 hypothetical protein. (319 aa) | ||||
Rcas_3037 | KEGG: rrs:RoseRS_2063 hypothetical protein. (330 aa) | ||||
ruvB | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (347 aa) | ||||
Rcas_3077 | PFAM: response regulator receiver; KEGG: sat:SYN_01078 response regulator receiver domain. (124 aa) | ||||
Rcas_3082 | KEGG: rrs:RoseRS_2397 hypothetical protein. (816 aa) | ||||
Rcas_3125 | PFAM: TPR repeat-containing protein; transcriptional activator domain; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: rrs:RoseRS_2354 transcriptional activator domain. (1068 aa) | ||||
Rcas_3134 | PFAM: response regulator receiver; KEGG: rrs:RoseRS_2347 response regulator receiver protein. (200 aa) | ||||
Rcas_3160 | Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rrs:RoseRS_2305 two component transcriptional regulator, winged helix family. (295 aa) | ||||
Rcas_3170 | KEGG: rrs:RoseRS_2295 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: PAS domain containing protein. (911 aa) | ||||
Rcas_3185 | KEGG: rrs:RoseRS_3081 hypothetical protein. (638 aa) | ||||
Rcas_3192 | TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; KEGG: rrs:RoseRS_3075 DNA polymerase III, delta subunit. (354 aa) | ||||
Rcas_3199 | PFAM: response regulator receiver; KEGG: rrs:RoseRS_0997 response regulator receiver protein. (126 aa) | ||||
Rcas_3231 | KEGG: rrs:RoseRS_3914 hypothetical protein. (251 aa) | ||||
nrdR | ATP-cone domain protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (152 aa) | ||||
Rcas_3262 | Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: rrs:RoseRS_1984 two component transcriptional regulator, LuxR family. (222 aa) | ||||
Rcas_3284 | KEGG: rrs:RoseRS_1850 hypothetical protein. (266 aa) | ||||
Rcas_3296 | Transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; KEGG: rrs:RoseRS_1863 response regulator receiver protein. (292 aa) | ||||
cas1-3 | CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (338 aa) | ||||
Rcas_3307 | KEGG: rrs:RoseRS_3876 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; CHASE4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. (1003 aa) | ||||
Rcas_3308 | PFAM: response regulator receiver; KEGG: rrs:RoseRS_3877 response regulator receiver protein. (130 aa) | ||||
Rcas_3349 | KEGG: rrs:RoseRS_3994 hypothetical protein. (742 aa) | ||||
Rcas_3352 | KEGG: rrs:RoseRS_4062 hypothetical protein. (123 aa) | ||||
Rcas_3376 | PFAM: UvrD/REP helicase; KEGG: rrs:RoseRS_2224 UvrD/REP helicase. (659 aa) | ||||
Rcas_3397 | PFAM: Translin; KEGG: rrs:RoseRS_1215 translin. (231 aa) | ||||
Rcas_3401 | Hypothetical protein. (95 aa) | ||||
Rcas_3427 | Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein Crp; KEGG: rrs:RoseRS_0292 putative transcriptional regulator, Crp/Fnr family. (223 aa) | ||||
lon-4 | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (836 aa) | ||||
Rcas_3457 | Transcriptional regulator, DeoR family; PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: rrs:RoseRS_2724 transcriptional regulator, DeoR family. (265 aa) | ||||
Rcas_3464 | Hypothetical protein; KEGG: mlo:mlr9643 transposase. (159 aa) | ||||
Rcas_3489 | PFAM: WD-40 repeat protein; SMART: serine/threonine protein kinase; KEGG: rrs:RoseRS_2154 WD-40 repeat protein. (1039 aa) | ||||
Rcas_3496 | Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: rrs:RoseRS_0051 transcriptional regulator, GntR family. (237 aa) | ||||
Rcas_3508 | Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: gtn:GTNG_2203 transcriptional regulator GntR family. (246 aa) | ||||
uvrB | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (670 aa) | ||||
mutS | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (1088 aa) | ||||
Rcas_3552 | KEGG: rrs:RoseRS_2269 hypothetical protein. (192 aa) | ||||
Rcas_3561 | PFAM: transposase IS4 family protein; KEGG: fra:Francci3_4220 transposase, IS4. (360 aa) | ||||
Rcas_3562 | Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; KEGG: rrs:RoseRS_1355 regulatory protein GntR, HTH. (319 aa) | ||||
Rcas_3593 | PFAM: DNA methylase N-4/N-6 domain protein; KEGG: rrs:RoseRS_0953 DNA methylase N-4/N-6 domain protein; Belongs to the N(4)/N(6)-methyltransferase family. (372 aa) | ||||
Rcas_3651 | Transposase, IS605 OrfB family; KEGG: noc:Noc_0388 transposase (probable), IS891/IS1136/IS1341; TIGRFAM: transposase, IS605 OrfB family; PFAM: putative transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB. (380 aa) | ||||
Rcas_3661 | Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rrs:RoseRS_4049 two component transcriptional regulator, winged helix family. (226 aa) | ||||
Rcas_3669 | PFAM: response regulator receiver; KEGG: rrs:RoseRS_4041 response regulator receiver protein. (127 aa) | ||||
Rcas_3679 | Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; SMART: regulatory protein Crp; KEGG: rrs:RoseRS_4027 cyclic nucleotide-binding protein. (216 aa) | ||||
Rcas_3693 | PFAM: DNA methylase N-4/N-6 domain protein; KEGG: ecs:ECs4134 putative methyltransferase; Belongs to the N(4)/N(6)-methyltransferase family. (332 aa) | ||||
Rcas_3701 | Transcriptional regulator, SARP family; PFAM: TPR repeat-containing protein; transcriptional regulator domain protein; transcriptional activator domain; Tetratricopeptide TPR_4; SMART: AAA ATPase; Tetratricopeptide domain protein; KEGG: gvi:glr1376 hypothetical protein. (1064 aa) | ||||
Rcas_3702 | PFAM: protein of unknown function DUF1568; KEGG: sus:Acid_5308 protein of unknown function DUF1568. (208 aa) | ||||
Rcas_3763 | Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: rrs:RoseRS_3278 two component transcriptional regulator, LuxR family. (221 aa) | ||||
Rcas_3827 | PFAM: response regulator receiver; KEGG: rrs:RoseRS_1955 response regulator receiver protein. (133 aa) | ||||
mutM | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (283 aa) | ||||
Rcas_3844 | Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: swi:Swit_0278 transcriptional regulator, GntR family. (260 aa) | ||||
Rcas_3852 | Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; KEGG: rrs:RoseRS_1355 regulatory protein GntR, HTH. (324 aa) | ||||
Rcas_3874 | PFAM: iron dependent repressor; FeoA family protein; KEGG: rrs:RoseRS_0550 FeoA family protein. (250 aa) | ||||
Rcas_3897 | Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; SMART: regulatory protein Crp; KEGG: rrs:RoseRS_0595 putative transcriptional regulator, Crp/Fnr family. (227 aa) | ||||
Rcas_3910 | PFAM: cyclic nucleotide-binding; KEGG: rrs:RoseRS_3727 cyclic nucleotide-binding protein. (167 aa) | ||||
Rcas_3945 | PFAM: regulatory protein AsnC/Lrp family; KEGG: rrs:RoseRS_1107 putative transcriptional regulator, AsnC family. (92 aa) | ||||
Rcas_3989 | TIGRFAM: primosome, DnaD subunit; PFAM: DnaD and phage-associated region; KEGG: rrs:RoseRS_1148 primosome, DnaD subunit. (239 aa) | ||||
Rcas_3990 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (444 aa) | ||||
rpoA | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (323 aa) | ||||
Rcas_4038 | PFAM: putative RNA methylase; KEGG: rrs:RoseRS_2251 hypothetical protein; Belongs to the N(4)/N(6)-methyltransferase family. (483 aa) | ||||
Rcas_4063 | PFAM: UvrD/REP helicase; KEGG: rrs:RoseRS_2259 UvrD/REP helicase. (697 aa) | ||||
Rcas_4064 | PFAM: transposase IS4 family protein; KEGG: pcu:pc1688 hypothetical protein. (278 aa) | ||||
Rcas_4106 | PFAM: protein of unknown function DUF156; KEGG: rrs:RoseRS_3295 protein of unknown function DUF156. (94 aa) | ||||
Rcas_4108 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: rrs:RoseRS_3810 RNA polymerase, sigma-24 subunit, ECF subfamily; Belongs to the sigma-70 factor family. ECF subfamily. (195 aa) | ||||
Rcas_4148 | KEGG: rrs:RoseRS_3359 putative circadian clock protein, KaiC; TIGRFAM: circadian clock protein KaiC; PFAM: Circadian clock protein KaiC central region; KaiA binding. (510 aa) | ||||
Rcas_4152 | PFAM: response regulator receiver; KEGG: rrs:RoseRS_3355 two component transcriptional regulator, fis family. (122 aa) | ||||
Rcas_4164 | PFAM: LIM zinc-binding protein; KEGG: rrs:RoseRS_3343 LIM, zinc-binding protein. (241 aa) | ||||
Rcas_4171 | PFAM: regulatory protein TetR; KEGG: rrs:RoseRS_4304 transcriptional regulator, TetR family. (203 aa) | ||||
Rcas_4183 | PFAM: DNA methylase N-4/N-6 domain protein; KEGG: xfa:XF0641 DNA methyltransferase; Belongs to the N(4)/N(6)-methyltransferase family. (370 aa) | ||||
Rcas_4189 | SMART: helix-turn-helix domain protein; KEGG: rrs:RoseRS_0059 helix-turn-helix domain protein. (206 aa) | ||||
gyrB | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (653 aa) | ||||
Rcas_4207 | PFAM: response regulator receiver; KEGG: rrs:RoseRS_0035 response regulator receiver protein. (120 aa) | ||||
Rcas_4215 | PFAM: regulatory protein TetR; KEGG: rrs:RoseRS_0027 transcriptional regulator, TetR family. (269 aa) | ||||
Rcas_4222 | PFAM: regulatory protein LuxR; Sigma-70 region 4 type 2; KEGG: reh:H16_B0754 transcriptional regulator, LuxR-family. (309 aa) | ||||
Rcas_4223 | PFAM: protein of unknown function DUF1568; KEGG: rba:RB693 hypothetical protein. (212 aa) | ||||
Rcas_4227 | Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: DNA-binding response regulator. (213 aa) | ||||
Rcas_4228 | PFAM: response regulator receiver; KEGG: tfu:Tfu_2233 regulatory protein, LuxR:response regulator receiver. (126 aa) | ||||
Rcas_4261 | PFAM: FeoA family protein; KEGG: rrs:RoseRS_0552 FeoA family protein. (84 aa) | ||||
Rcas_4275 | TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: rrs:RoseRS_3588 DNA polymerase III, delta prime subunit. (354 aa) | ||||
Rcas_4276 | PFAM: response regulator receiver; KEGG: rrs:RoseRS_3589 response regulator receiver protein. (128 aa) | ||||
Rcas_4293 | KEGG: rrs:RoseRS_1243 hypothetical protein. (539 aa) | ||||
Rcas_4298 | Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rrs:RoseRS_3608 two component transcriptional regulator, winged helix family. (227 aa) | ||||
Rcas_4302 | PFAM: response regulator receiver; KEGG: rrs:RoseRS_3612 response regulator receiver protein. (124 aa) | ||||
Rcas_4312 | KEGG: rrs:RoseRS_4066 hypothetical protein. (163 aa) | ||||
nusG | NusG antitermination factor; Participates in transcription elongation, termination and antitermination. (194 aa) | ||||
Rcas_4327 | ATP-dependent transcriptional regulator, MalT-like, LuxR family; PFAM: regulatory protein LuxR; KEGG: rrs:RoseRS_2963 regulatory protein, LuxR. (1021 aa) | ||||
Rcas_4338 | KEGG: rrs:RoseRS_0201 hypothetical protein. (267 aa) | ||||
Rcas_4344 | Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rrs:RoseRS_0195 two component transcriptional regulator, winged helix family. (239 aa) | ||||
sigA-3 | RNA polymerase, sigma 70 subunit, RpoD family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (399 aa) | ||||
Rcas_4351 | Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rrs:RoseRS_0188 two component transcriptional regulator, winged helix family. (245 aa) | ||||
Rcas_4363 | Iron (metal) dependent repressor, DtxR family; PFAM: iron dependent repressor; KEGG: rrs:RoseRS_3574 iron dependent repressor. (236 aa) | ||||
Rcas_4388 | KEGG: rrs:RoseRS_2687 type I site-specific deoxyribonuclease, HsdR family. (53 aa) | ||||
hrcA | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. (359 aa) | ||||
Rcas_4396 | TIGRFAM: integron integrase; PFAM: integrase family protein; KEGG: mfa:Mfla_0410 integron integrase; Belongs to the 'phage' integrase family. (318 aa) | ||||
Rcas_4397 | KEGG: rrs:RoseRS_2284 hypothetical protein. (475 aa) | ||||
Rcas_4398 | Endonuclease; KEGG: xoo:XOO0608 endonuclease. (264 aa) | ||||
uvrA-2 | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (1043 aa) | ||||
Rcas_4428 | Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; Bacterio-opsin activator HTH domain protein; Helix-turn-helix type 11 domain protein; Sigma-70 region 4 type 2; KEGG: rrs:RoseRS_4323 two component transcriptional regulator, LuxR family. (231 aa) | ||||
Rcas_4445 | Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rrs:RoseRS_0761 two component transcriptional regulator, winged helix family. (229 aa) | ||||
Rcas_0278 | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: rrs:RoseRS_0258 transcriptional regulator, XRE family. (110 aa) | ||||
Rcas_0291 | Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein Crp; KEGG: rrs:RoseRS_0244 putative transcriptional regulator, Crp/Fnr family. (227 aa) | ||||
gyrA | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (823 aa) | ||||
Rcas_0353 | Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rrs:RoseRS_0114 two component transcriptional regulator, winged helix family. (230 aa) | ||||
Rcas_0356 | TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: rrs:RoseRS_0117 ParB-like partition protein; Belongs to the ParB family. (301 aa) | ||||
Rcas_0374 | PFAM: response regulator receiver; KEGG: rrs:RoseRS_4608 response regulator receiver protein. (141 aa) | ||||
Rcas_0387 | PFAM: NUDIX hydrolase; KEGG: rrs:RoseRS_0145 NUDIX hydrolase; Belongs to the Nudix hydrolase family. (252 aa) | ||||
Rcas_0389 | PFAM: UvrD/REP helicase; KEGG: rrs:RoseRS_0142 UvrD/REP helicase. (759 aa) | ||||
Rcas_0397 | PFAM: DNA methylase N-4/N-6 domain protein; KEGG: aeh:Mlg_1539 DNA methylase N-4/N-6 domain protein. (1028 aa) | ||||
Rcas_0399 | PFAM: type III restriction protein res subunit; KEGG: mem:Memar_1479 type III restriction enzyme, res subunit. (1104 aa) | ||||
Rcas_0405 | PFAM: transposase IS4 family protein; KEGG: rrs:RoseRS_0444 transposase, IS4 family protein. (383 aa) | ||||
Rcas_0407 | KEGG: ana:all3632 site-specific DNA-methyltransferase (cytosine-specific). (476 aa) | ||||
Rcas_0408 | KEGG: ana:all3631 type II site-specific deoxyribonuclease. (320 aa) | ||||
Rcas_0411 | PFAM: transposase IS4 family protein; KEGG: rrs:RoseRS_0444 transposase, IS4 family protein. (383 aa) | ||||
Rcas_0412 | Hypothetical protein; KEGG: mem:Memar_1479 type III restriction enzyme, res subunit. (643 aa) | ||||
sigA-2 | RNA polymerase, sigma 70 subunit, RpoD family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (405 aa) | ||||
Rcas_0421 | Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rrs:RoseRS_4619 two component transcriptional regulator, winged helix family. (245 aa) | ||||
Rcas_0474 | PFAM: restriction endonuclease; SH3 type 3 domain protein; KEGG: rrs:RoseRS_4245 restriction endonuclease. (364 aa) | ||||
Rcas_0485 | PFAM: protein of unknown function DUF218; KEGG: rrs:RoseRS_3653 protein of unknown function DUF218. (225 aa) | ||||
Rcas_0512 | Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: rrs:RoseRS_3623 periplasmic binding protein/LacI transcriptional regulator. (336 aa) | ||||
nfo | Apurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (289 aa) | ||||
Rcas_0569 | PFAM: transcriptional regulator domain protein; KEGG: rrs:RoseRS_3851 putative two component transcriptional regulator, winged helix family. (458 aa) | ||||
uvrA | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (976 aa) | ||||
Rcas_0592 | KEGG: rrs:RoseRS_4160 signal transduction histidine kinase, nitrogen specific, NtrB; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. (516 aa) | ||||
Rcas_0593 | Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rrs:RoseRS_4161 two component transcriptional regulator, winged helix family. (267 aa) | ||||
Rcas_0616 | PFAM: integrase family protein; KEGG: rrs:RoseRS_0840 integron integrase. (229 aa) | ||||
Rcas_0617 | KEGG: syf:Synpcc7942_B2653 transcriptional modulator of MazE/toxin, MazF. (115 aa) | ||||
Rcas_0618 | KEGG: pth:PTH_0862 hypothetical protein. (200 aa) | ||||
Rcas_0670 | PFAM: response regulator receiver; KEGG: noc:Noc_1329 response regulator receiver. (121 aa) | ||||
Rcas_0671 | KEGG: noc:Noc_1328 KaiC; PFAM: Circadian clock protein KaiC central region; KaiA binding; SMART: AAA ATPase. (535 aa) | ||||
Rcas_0673 | Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (92 aa) | ||||
Rcas_0674 | PFAM: response regulator receiver; KEGG: rrs:RoseRS_0161 response regulator receiver protein. (120 aa) | ||||
Rcas_0689 | PFAM: transcriptional regulator domain protein; KEGG: rrs:RoseRS_0151 putative two component transcriptional regulator, winged helix family. (461 aa) | ||||
Rcas_0696 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: rrs:RoseRS_0090 RNA polymerase, sigma-24 subunit, ECF subfamily; Belongs to the sigma-70 factor family. ECF subfamily. (211 aa) | ||||
Rcas_0699 | PFAM: transcriptional activator domain; SMART: Tetratricopeptide domain protein; KEGG: rrs:RoseRS_4345 transcriptional activator domain. (1094 aa) | ||||
Rcas_0718 | PFAM: protein of unknown function DUF28; KEGG: rrs:RoseRS_4362 protein of unknown function DUF28. (255 aa) | ||||
Rcas_0731 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: rrs:RoseRS_4389 RNA polymerase, sigma-24 subunit, ECF subfamily; Belongs to the sigma-70 factor family. ECF subfamily. (201 aa) |