node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rcas_0581 | Rcas_0881 | Rcas_0581 | Rcas_0881 | KEGG: rrs:RoseRS_3488 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.997 |
Rcas_0581 | Rcas_0925 | Rcas_0581 | Rcas_0925 | KEGG: rrs:RoseRS_3488 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | PFAM: fumarate lyase; KEGG: rrs:RoseRS_3341 fumarate lyase. | 0.850 |
Rcas_0581 | Rcas_1241 | Rcas_0581 | Rcas_1241 | KEGG: rrs:RoseRS_3488 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: rrs:RoseRS_0785 isocitrate dehydrogenase, NADP-dependent. | 0.867 |
Rcas_0581 | Rcas_1532 | Rcas_0581 | Rcas_1532 | KEGG: rrs:RoseRS_3488 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | KEGG: rrs:RoseRS_3396 2-oxoglutarate dehydrogenase, E1 subunit; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase E1 component; Transketolase central region. | 0.907 |
Rcas_0581 | Rcas_2967 | Rcas_0581 | Rcas_2967 | KEGG: rrs:RoseRS_3488 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | 0.835 |
Rcas_0581 | Rcas_3081 | Rcas_0581 | Rcas_3081 | KEGG: rrs:RoseRS_3488 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: rrs:RoseRS_2398 succinate dehydrogenase and fumarate reductase iron-sulfur protein. | 0.922 |
Rcas_0581 | Rcas_4376 | Rcas_0581 | Rcas_4376 | KEGG: rrs:RoseRS_3488 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | KEGG: rrs:RoseRS_4165 malate synthase A; TIGRFAM: malate synthase A; PFAM: malate synthase. | 0.970 |
Rcas_0581 | mdh | Rcas_0581 | Rcas_0283 | KEGG: rrs:RoseRS_3488 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.996 |
Rcas_0581 | ppc | Rcas_0581 | Rcas_2377 | KEGG: rrs:RoseRS_3488 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | 0.835 |
Rcas_0581 | sucC | Rcas_0581 | Rcas_3203 | KEGG: rrs:RoseRS_3488 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.977 |
Rcas_0581 | sucD | Rcas_0581 | Rcas_3739 | KEGG: rrs:RoseRS_3488 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.801 |
Rcas_0881 | Rcas_0581 | Rcas_0881 | Rcas_0581 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | KEGG: rrs:RoseRS_3488 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | 0.997 |
Rcas_0881 | Rcas_1241 | Rcas_0881 | Rcas_1241 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: rrs:RoseRS_0785 isocitrate dehydrogenase, NADP-dependent. | 0.988 |
Rcas_0881 | Rcas_1532 | Rcas_0881 | Rcas_1532 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | KEGG: rrs:RoseRS_3396 2-oxoglutarate dehydrogenase, E1 subunit; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase E1 component; Transketolase central region. | 0.631 |
Rcas_0881 | Rcas_3081 | Rcas_0881 | Rcas_3081 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: rrs:RoseRS_2398 succinate dehydrogenase and fumarate reductase iron-sulfur protein. | 0.867 |
Rcas_0881 | Rcas_4376 | Rcas_0881 | Rcas_4376 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | KEGG: rrs:RoseRS_4165 malate synthase A; TIGRFAM: malate synthase A; PFAM: malate synthase. | 0.425 |
Rcas_0881 | mdh | Rcas_0881 | Rcas_0283 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.587 |
Rcas_0881 | sucC | Rcas_0881 | Rcas_3203 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.434 |
Rcas_0881 | sucD | Rcas_0881 | Rcas_3739 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.570 |
Rcas_0925 | Rcas_0581 | Rcas_0925 | Rcas_0581 | PFAM: fumarate lyase; KEGG: rrs:RoseRS_3341 fumarate lyase. | KEGG: rrs:RoseRS_3488 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | 0.850 |