STRINGSTRING
pdhA pdhA Rcas_0041 Rcas_0041 Rcas_0272 Rcas_0272 Rcas_0611 Rcas_0611 Rcas_0715 Rcas_0715 Rcas_1157 Rcas_1157 Rcas_1222 Rcas_1222 Rcas_1532 Rcas_1532 Rcas_1863 Rcas_1863 Rcas_1946 Rcas_1946 hemA hemA Rcas_2305 Rcas_2305 Rcas_2308 Rcas_2308 Rcas_2314 Rcas_2314 Rcas_2406 Rcas_2406 Rcas_2411 Rcas_2411 Rcas_2932 Rcas_2932 Rcas_3063 Rcas_3063 Rcas_3188 Rcas_3188 Rcas_3194 Rcas_3194 Rcas_3283 Rcas_3283 argC argC lysY lysY Rcas_3504 Rcas_3504 Rcas_3575 Rcas_3575 Rcas_3577 Rcas_3577 proA proA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pdhAPyruvate dehydrogenase (acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (353 aa)
Rcas_0041PFAM: aldehyde dehydrogenase; KEGG: rrs:RoseRS_4193 aldehyde dehydrogenase. (484 aa)
Rcas_0272PFAM: aldehyde dehydrogenase; KEGG: rrs:RoseRS_0265 aldehyde dehydrogenase (NAD(+)); Belongs to the aldehyde dehydrogenase family. (517 aa)
Rcas_0611PFAM: aldehyde dehydrogenase; acyl-CoA reductase; KEGG: rrs:RoseRS_3490 aldehyde dehydrogenase. (478 aa)
Rcas_0715PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; KEGG: rrs:RoseRS_4359 aldehyde ferredoxin oxidoreductase. (596 aa)
Rcas_1157PFAM: glyceraldehyde 3-phosphate dehydrogenase; KEGG: rrs:RoseRS_0387 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (332 aa)
Rcas_1222PFAM: aldehyde dehydrogenase; KEGG: rrs:RoseRS_0829 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (497 aa)
Rcas_1532KEGG: rrs:RoseRS_3396 2-oxoglutarate dehydrogenase, E1 subunit; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase E1 component; Transketolase central region. (953 aa)
Rcas_1863PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; KEGG: tth:TTC1834 tungsten-containing aldehyde ferredoxin oxidoreductase. (609 aa)
Rcas_1946Transketolase central region; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (795 aa)
hemAGlutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (425 aa)
Rcas_2305TIGRFAM: putative delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: rrs:RoseRS_1548 putative delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (516 aa)
Rcas_2308PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rrs:RoseRS_1551 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (615 aa)
Rcas_2314KEGG: rrs:RoseRS_1226 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)
Rcas_2406PFAM: aldehyde dehydrogenase; KEGG: rrs:RoseRS_2577 aldehyde dehydrogenase. (484 aa)
Rcas_2411Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (305 aa)
Rcas_2932PFAM: aldehyde dehydrogenase; KEGG: rrs:RoseRS_3204 aldehyde dehydrogenase. (515 aa)
Rcas_3063PFAM: dehydrogenase E1 component; KEGG: rrs:RoseRS_2415 pyruvate dehydrogenase (acetyl-transferring). (333 aa)
Rcas_3188KEGG: rrs:RoseRS_3078 aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; Belongs to the aspartate-semialdehyde dehydrogenase family. (352 aa)
Rcas_3194KEGG: rrs:RoseRS_3073 hypothetical protein. (574 aa)
Rcas_3283KEGG: rrs:RoseRS_1851 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (347 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (336 aa)
lysYN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of [LysW]- aminoadipate 6-phosphate to yield [LysW]-aminoadipate 6-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. (348 aa)
Rcas_3504PFAM: aldehyde dehydrogenase; KEGG: ana:all5022 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (474 aa)
Rcas_3575PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: rrs:RoseRS_1368 pyruvate ferredoxin/flavodoxin oxidoreductase. (183 aa)
Rcas_3577PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: rrs:RoseRS_1370 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (367 aa)
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (423 aa)
Your Current Organism:
Roseiflexus castenholzii
NCBI taxonomy Id: 383372
Other names: R. castenholzii DSM 13941, Roseiflexus castenholzii DSM 13941, Roseiflexus castenholzii HLO8, Roseiflexus castenholzii str. DSM 13941, Roseiflexus castenholzii strain DSM 13941
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.