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Rcas_2308 Rcas_2308 Rcas_2048 Rcas_2048 Rcas_0594 Rcas_0594 Rcas_1663 Rcas_1663 Rcas_1692 Rcas_1692 Rcas_1946 Rcas_1946 Rcas_2012 Rcas_2012 pdhA pdhA Rcas_4116 Rcas_4116 Rcas_4052 Rcas_4052 Rcas_3577 Rcas_3577 Rcas_3575 Rcas_3575 Rcas_3524 Rcas_3524 Rcas_3515 Rcas_3515 Rcas_3494 Rcas_3494 Rcas_3467 Rcas_3467 Rcas_3272 Rcas_3272 Rcas_3063 Rcas_3063 Rcas_2967 Rcas_2967 pckG pckG Rcas_2482 Rcas_2482
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Rcas_2308PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rrs:RoseRS_1551 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (615 aa)
Rcas_2048TIGRFAM: phosphocarrier, HPr family; phosphoenolpyruvate-protein phosphotransferase; dihydroxyacetone kinase, phosphotransfer subunit; PFAM: phosphocarrier HPr protein; PEP-utilizing protein; PTS system fructose subfamily IIA component; PEP-utilising protein mobile region; PEP-utilising protein domain protein; KEGG: rrs:RoseRS_1770 phosphoenolpyruvate-protein phosphotransferase; Belongs to the PEP-utilizing enzyme family. (838 aa)
Rcas_0594PFAM: pyruvate carboxyltransferase; KEGG: rrs:RoseRS_4162 pyruvate carboxyltransferase. (313 aa)
Rcas_1663PFAM: phosphatidylserine decarboxylase-related; KEGG: rrs:RoseRS_1290 phosphatidylserine decarboxylase-like protein. (225 aa)
Rcas_1692KEGG: rrs:RoseRS_1428 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. (479 aa)
Rcas_1946Transketolase central region; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (795 aa)
Rcas_2012Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (322 aa)
pdhAPyruvate dehydrogenase (acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (353 aa)
Rcas_4116Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (556 aa)
Rcas_4052PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rrs:RoseRS_1213 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (1192 aa)
Rcas_3577PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: rrs:RoseRS_1370 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (367 aa)
Rcas_3575PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: rrs:RoseRS_1368 pyruvate ferredoxin/flavodoxin oxidoreductase. (183 aa)
Rcas_3524KEGG: rrs:RoseRS_2148 pyruvate-formate lyase-activating enzyme-like protein. (330 aa)
Rcas_3515PFAM: pyruvate carboxyltransferase; KEGG: sru:SRU_1246 3-hydroxy-3-methylglutaryl-CoA lyase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (297 aa)
Rcas_3494PFAM: pyruvate carboxyltransferase; KEGG: rrs:RoseRS_0049 pyruvate carboxyltransferase. (317 aa)
Rcas_3467PFAM: pyruvate carboxyltransferase; KEGG: rrs:RoseRS_1061 pyruvate carboxyltransferase. (707 aa)
Rcas_3272Hydroxypyruvate reductase; PFAM: MOFRL domain protein; KEGG: rrs:RoseRS_1997 hydroxypyruvate reductase. (458 aa)
Rcas_3063PFAM: dehydrogenase E1 component; KEGG: rrs:RoseRS_2415 pyruvate dehydrogenase (acetyl-transferring). (333 aa)
Rcas_2967Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (910 aa)
pckGPhosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (619 aa)
Rcas_2482KEGG: rrs:RoseRS_1064 pyruvate, phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing protein; pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; Belongs to the PEP-utilizing enzyme family. (889 aa)
Your Current Organism:
Roseiflexus castenholzii
NCBI taxonomy Id: 383372
Other names: R. castenholzii DSM 13941, Roseiflexus castenholzii DSM 13941, Roseiflexus castenholzii HLO8, Roseiflexus castenholzii str. DSM 13941, Roseiflexus castenholzii strain DSM 13941
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