STRINGSTRING
Rcas_0076 Rcas_0076 Rcas_0117 Rcas_0117 Rcas_0152 Rcas_0152 Rcas_0702 Rcas_0702 Rcas_0983 Rcas_0983 accA accA accD1 accD1 Rcas_2019 Rcas_2019 Rcas_2104 Rcas_2104 Rcas_2556 Rcas_2556 Rcas_2882 Rcas_2882 Rcas_2899 Rcas_2899 accD2 accD2 accA-2 accA-2 Rcas_2929 Rcas_2929 Rcas_2931 Rcas_2931 Rcas_2933 Rcas_2933 Rcas_2955 Rcas_2955 Rcas_2998 Rcas_2998 Rcas_3062 Rcas_3062 Rcas_3063 Rcas_3063 mgsA mgsA sucC sucC Rcas_3206 Rcas_3206 Rcas_3219 Rcas_3219 sucD sucD Rcas_3871 Rcas_3871 Rcas_3872 Rcas_3872 Rcas_3934 Rcas_3934 Rcas_3935 Rcas_3935 Rcas_4290 Rcas_4290 Rcas_4326 Rcas_4326
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Rcas_0076TIGRFAM: Acetyl coenzyme A synthetase (ADP forming) alpha domain; PFAM: CoA-binding domain protein; KEGG: rrs:RoseRS_4534 CoA-binding domain protein. (698 aa)
Rcas_0117PFAM: aminotransferase class-III; KEGG: rrs:RoseRS_4570 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (453 aa)
Rcas_0152PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: rrs:RoseRS_0480 glyoxalase/bleomycin resistance protein/dioxygenase. (134 aa)
Rcas_0702KEGG: rrs:RoseRS_4348 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
Rcas_0983KEGG: rrs:RoseRS_0429 acetyl-CoA acetyltransferase-like protein. (384 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (287 aa)
accD1acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (298 aa)
Rcas_2019PFAM: aminotransferase class-III; KEGG: rrs:RoseRS_1738 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (465 aa)
Rcas_2104TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; FAD dependent oxidoreductase; KEGG: rrs:RoseRS_3003 dihydrolipoamide dehydrogenase. (471 aa)
Rcas_2556PFAM: beta-lactamase; KEGG: rrs:RoseRS_2777 beta-lactamase. (395 aa)
Rcas_2882Carbamoyl-phosphate synthase L chain ATP-binding; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: rrs:RoseRS_2908 biotin carboxylase domain protein. (493 aa)
Rcas_2899acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (182 aa)
accD2acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (328 aa)
accA-2acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (276 aa)
Rcas_2929PFAM: short-chain dehydrogenase/reductase SDR; Male sterility domain; KEGG: rrs:RoseRS_3201 short-chain dehydrogenase/reductase SDR. (1229 aa)
Rcas_2931acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (454 aa)
Rcas_2933TIGRFAM: Quinone oxidoreductase putative YhdH/YhfP; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: rrs:RoseRS_3205 alcohol dehydrogenase, zinc-binding domain protein. (332 aa)
Rcas_2955PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: cph:Cpha266_1064 carbamoyl-phosphate synthase L chain, ATP-binding. (484 aa)
Rcas_2998PFAM: cobalamin B12-binding domain protein; KEGG: rrs:RoseRS_2024 cobalamin B12-binding domain protein. (134 aa)
Rcas_3062PFAM: Transketolase central region; Transketolase domain protein; KEGG: rrs:RoseRS_2416 transketolase, central region. (327 aa)
Rcas_3063PFAM: dehydrogenase E1 component; KEGG: rrs:RoseRS_2415 pyruvate dehydrogenase (acetyl-transferring). (333 aa)
mgsAMethylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (134 aa)
sucCsuccinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (379 aa)
Rcas_3206KEGG: rrs:RoseRS_3911 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
Rcas_3219PFAM: aminotransferase class-III; KEGG: rrs:RoseRS_3926 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (442 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
Rcas_3871KEGG: rrs:RoseRS_0544 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase. (720 aa)
Rcas_3872KEGG: rrs:RoseRS_0545 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. (740 aa)
Rcas_3934acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (639 aa)
Rcas_3935acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (650 aa)
Rcas_4290acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (591 aa)
Rcas_4326KEGG: rrs:RoseRS_0214 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase. (563 aa)
Your Current Organism:
Roseiflexus castenholzii
NCBI taxonomy Id: 383372
Other names: R. castenholzii DSM 13941, Roseiflexus castenholzii DSM 13941, Roseiflexus castenholzii HLO8, Roseiflexus castenholzii str. DSM 13941, Roseiflexus castenholzii strain DSM 13941
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