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glyA-1 glyA-1 PSEEN2008 PSEEN2008 sda-3 sda-3 ilvA-1 ilvA-1 PSEEN3862 PSEEN3862 PSEEN3999 PSEEN3999 thrC thrC hom hom sdaA-2 sdaA-2 serB serB PSEEN5013 PSEEN5013 sdaA sdaA ilvA-2 ilvA-2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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glyA-1Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa)
PSEEN2008Putative L-serine dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (305 aa)
sda-3L-serine deaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa)
ilvA-1Threonine dehydratase biosynthetic (Threonine deaminase); Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (520 aa)
PSEEN3862Threonine synthase; Function of strongly homologous gene; enzyme. (414 aa)
PSEEN3999Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (321 aa)
thrCThreonine synthase; Function of strongly homologous gene; enzyme. (469 aa)
homHomoserine dehydrogenase; Function of strongly homologous gene; enzyme. (450 aa)
sdaA-2L-serine deaminase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa)
serBPhosphoserine phosphatase; Function of strongly homologous gene; enzyme. (415 aa)
PSEEN5013Putative threonine dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (325 aa)
sdaAL-serine deaminase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the iron-sulfur dependent L-serine dehydratase family. (435 aa)
ilvA-2Threonine deaminase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (504 aa)
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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