5 items (Pseudomonas entomophila) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	folE	Putative GTP cyclohydrolase I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (202 aa)
	ribB/A	3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (363 aa)
	ribA	GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (205 aa)
	folE2	GTP cyclohydrolase I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (181 aa)
	folE2-2	Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. (293 aa)

Your Current Organism:

Pseudomonas entomophila

NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
folE	folE2	PSEEN2519	PSEEN1521	Putative GTP cyclohydrolase I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.	GTP cyclohydrolase I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.	0.909
folE	folE2-2	PSEEN2519	PSEEN5515	Putative GTP cyclohydrolase I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.	Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.	0.916
folE	ribA	PSEEN2519	PSEEN0596	Putative GTP cyclohydrolase I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.	GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.	0.919
folE	ribB/A	PSEEN2519	PSEEN0590	Putative GTP cyclohydrolase I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.	3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.	0.940
folE2	folE	PSEEN1521	PSEEN2519	GTP cyclohydrolase I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.	Putative GTP cyclohydrolase I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.	0.909
folE2	folE2-2	PSEEN1521	PSEEN5515	GTP cyclohydrolase I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.	Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.	0.916
folE2	ribA	PSEEN1521	PSEEN0596	GTP cyclohydrolase I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.	GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.	0.919
folE2	ribB/A	PSEEN1521	PSEEN0590	GTP cyclohydrolase I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.	3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.	0.940
folE2-2	folE	PSEEN5515	PSEEN2519	Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.	Putative GTP cyclohydrolase I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.	0.916
folE2-2	folE2	PSEEN5515	PSEEN1521	Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.	GTP cyclohydrolase I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.	0.916
folE2-2	ribA	PSEEN5515	PSEEN0596	Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.	GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.	0.902
folE2-2	ribB/A	PSEEN5515	PSEEN0590	Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.	3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.	0.906
ribA	folE	PSEEN0596	PSEEN2519	GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.	Putative GTP cyclohydrolase I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.	0.919
ribA	folE2	PSEEN0596	PSEEN1521	GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.	GTP cyclohydrolase I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.	0.919
ribA	folE2-2	PSEEN0596	PSEEN5515	GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.	Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.	0.902
ribA	ribB/A	PSEEN0596	PSEEN0590	GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.	3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.	0.966
ribB/A	folE	PSEEN0590	PSEEN2519	3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.	Putative GTP cyclohydrolase I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.	0.940
ribB/A	folE2	PSEEN0590	PSEEN1521	3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.	GTP cyclohydrolase I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.	0.940
ribB/A	folE2-2	PSEEN0590	PSEEN5515	3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.	Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.	0.906
ribB/A	ribA	PSEEN0590	PSEEN0596	3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.	GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.	0.966