STRINGSTRING
PSEEN4608 PSEEN4608 srkA srkA stk1 stk1 PSEEN1741 PSEEN1741 PSEEN1751 PSEEN1751 PSEEN2280 PSEEN2280 aceK aceK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
PSEEN4608Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (268 aa)
srkAConserved hypothetical protein; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. (324 aa)
stk1Serine-threonine kinase Stk1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (352 aa)
PSEEN1741Conserved hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. (272 aa)
PSEEN1751Putative bifunctional serine/threonine-protein kinase and phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (556 aa)
PSEEN2280Putative signal transduction protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator. (481 aa)
aceKIsocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. (571 aa)
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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