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| | folB | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (118 aa) |
| | trpA | Tryptophan synthase alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (269 aa) |
| | trpB | Tryptophan synthase beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (405 aa) |
| | cynT-2 | Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (239 aa) |
| | PSEEN0106 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (133 aa) |
| | pck | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (513 aa) |
| | rmlB | dTDP-D-glucose-4,6-dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (361 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the IlvD/Edd family. (613 aa) |
| | mutM | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (270 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (365 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (354 aa) |
| | PSEEN0347 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (156 aa) |
| | PSEEN0356 | Putative phenylalanine/histidine ammonia-lyase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (514 aa) |
| | PSEEN0359 | Putative AMP-binding enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (556 aa) |
| | aroQ-2 | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (149 aa) |
| | PSEEN2115 | Putative thiamine pyrophosphate; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the TPP enzyme family. (526 aa) |
| | PSEEN2151 | Putative Ornithine cyclodeaminase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (341 aa) |
| | purB | Adenylosuccinate lyase; Function of strongly homologous gene; enzyme; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (456 aa) |
| | cysG | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. (463 aa) |
| | PSEEN2360 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (282 aa) |
| | nspC | Carboxynorspermidine decarboxylase NspC; Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine; Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily. (365 aa) |
| | PSEEN2370 | Putative tyrosine decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (469 aa) |
| | PSEEN2380 | Putative dihydrodipicolinate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the DapA family. (297 aa) |
| | sda-3 | L-serine deaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa) |
| | PSEEN2474 | Putative 3-dehydroquinate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (392 aa) |
| | pmsA | Histidine decarboxylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (403 aa) |
| | psmB | Isochorismate pyruvate-lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (105 aa) |
| | queE | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (229 aa) |
| | PSEEN2520 | Putative 6-pyruvoyl-tetrahydropterin synthase-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (175 aa) |
| | PSEEN2523 | Hypothetical protein; No homology to any previously reported sequences; Belongs to the UbiD family. (412 aa) |
| | PSEEN2564 | Putative Ribonuclease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the RNase T2 family. (256 aa) |
| | PSEEN2585 | Putative class II aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (267 aa) |
| | hutH-2 | Histidine ammonia-lyase; Function of strongly homologous gene; enzyme. (507 aa) |
| | PSEEN2628 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (267 aa) |
| | PSEEN2641 | Putative 3-dehydroquinate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (624 aa) |
| | garD | D-galactarate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (517 aa) |
| | kdgD | 5-dehydro-4-deoxyglucarate dehydratase (5-keto-4-deoxy-glucarate dehydratase); Function of strongly homologous gene; enzyme; Belongs to the DapA family. (305 aa) |
| | PSEEN2739 | Putative photolyase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (513 aa) |
| | PSEEN2811 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (229 aa) |
| | PSEEN2812 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (318 aa) |
| | PSEEN2870 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (284 aa) |
| | PSEEN2922 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (302 aa) |
| | ilvA-1 | Threonine dehydratase biosynthetic (Threonine deaminase); Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (520 aa) |
| | mvaB | hydroxymethylglutaryl-CoA lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (299 aa) |
| | ribB/A-2 | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (370 aa) |
| | PSEEN3053 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (229 aa) |
| | hpaG-1 | 4-hydroxyphenylacetate degradation; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (224 aa) |
| | hpaH | 2-oxo-hepta-3-ene-1,7-dioic acid hydratase (OHED hydratase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (267 aa) |
| | hpaI | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, with PEP/pyruvate domain; Function of strongly homologous gene; enzyme; Belongs to the HpcH/HpaI aldolase family. (266 aa) |
| | gloA | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (175 aa) |
| | PSEEN3315 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (425 aa) |
| | PSEEN3422 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (133 aa) |
| | PSEEN3423 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (243 aa) |
| | PSEEN3462 | Putative alginate lyase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (369 aa) |
| | aceA | Isocitrate lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (441 aa) |
| | PSEEN3557 | Putative arginine/lysine/ornithine decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (746 aa) |
| | cynS | Cyanate aminohydrolase (cyanase); Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family. (156 aa) |
| | cynT-1 | Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (219 aa) |
| | lysA-1 | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (409 aa) |
| | fabA | Beta-hydroxydecanoyl thioester dehydrase (trans-2-decenoyl-ACP isomerase); Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (171 aa) |
| | PSEEN3672 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (126 aa) |
| | fadB | Fatty oxidation complex alpha subunit [Includes: Enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (715 aa) |
| | acnA | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (913 aa) |
| | PSEEN3862 | Threonine synthase; Function of strongly homologous gene; enzyme. (414 aa) |
| | phhB | Pterin-4-alpha-carbinolamine dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (118 aa) |
| | PSEEN3956 | Putative phosphoenolpyruvate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (296 aa) |
| | phaJ1 | enoyl-CoA hydratase, R-specific; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (156 aa) |
| | PSEEN3999 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (321 aa) |
| | cysK | Cysteine synthase A; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (324 aa) |
| | PSEEN4039 | Putative cystathionine gamma-synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (391 aa) |
| | moaA | Putative molybdopterin biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (334 aa) |
| | PSEEN4051 | Putative dihydrodipicolinate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the DapA family. (315 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (295 aa) |
| | queE-2 | Putative radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (215 aa) |
| | ispF | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (157 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (429 aa) |
| | fabZ | (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (146 aa) |
| | PSEEN4230 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (269 aa) |
| | thrC | Threonine synthase; Function of strongly homologous gene; enzyme. (469 aa) |
| | PSEEN4356 | Putative carboxyphosphonoenolpyruvate phosphonomutase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family. (289 aa) |
| | mltF-2 | Putative periplasmic binding domain/transglycosylase SLT domain fusion protein; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial so [...] (463 aa) |
| | eda | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (224 aa) |
| | edd | Phosphogluconate dehydratase (6-phosphogluconate dehydratase); Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (608 aa) |
| | sdaA-2 | L-serine deaminase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa) |
| | mdeA | Methionine gamma-lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (398 aa) |
| | moaC | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (156 aa) |
| | algL | Alginate lyase AlgL; Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism. May serve to degrade mislocalized alginate that is trapped in the periplasmic space. (367 aa) |
| | rmlB-2 | dTDP-D-glucose-4,6-dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (339 aa) |
| | ubiC1 | Putative chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. (185 aa) |
| | PSEEN4772 | Putative ferredoxin--NADP+ reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (258 aa) |
| | rlpA-2 | Putative lipoprotein, rare lipoprotein A family; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (332 aa) |
| | speA | Arginine decarboxylase, PLP-binding, biosynthetic; Catalyzes the biosynthesis of agmatine from arginine. (637 aa) |
| | aroQ-1 | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (150 aa) |
| | nnrD | Conserved hypothetical protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. (283 aa) |
| | psd | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (287 aa) |
| | thiC | Hydroxymethylpyrimidine moiety synthesis in thiamin biosynthesis; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (626 aa) |
| | PSEEN5012 | Ornithine cyclodeaminase, mu-crystallin homolog; Function of strongly homologous gene; enzyme. (315 aa) |
| | PSEEN5013 | Putative threonine dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (325 aa) |
| | fda | Fructose-1,6-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa) |
| | PSEEN5030 | Putative outer membrane-bound lytic murein transglycolase A; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. (383 aa) |
| | hutH | Histidine ammonia-lyase; Function of strongly homologous gene; enzyme. (510 aa) |
| | hutU | Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (557 aa) |
| | ltaE | Low-specificity L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (346 aa) |
| | sdaA | L-serine deaminase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the iron-sulfur dependent L-serine dehydratase family. (435 aa) |
| | hisF | Imidazole glycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (256 aa) |
| | hisH | Imidazole glycerol phosphate synthetase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (212 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase; Function of strongly homologous gene; enzyme. (197 aa) |
| | ilvA-2 | Threonine deaminase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (504 aa) |
| | PSEEN5327 | Putative transporter, ChaC-related; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (216 aa) |
| | ubiD | 3-octaprenyl-4-hydroxybenzoate decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. (488 aa) |
| | hemB | Delta-aminolevulinic acid dehydratase (Porphobilinogen synthase); Function of strongly homologous gene; enzyme; Belongs to the ALAD family. (336 aa) |
| | elbB | Enhancing lycopene biosynthesis protein 2; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate; Belongs to the peptidase C56 family. (222 aa) |
| | hemD | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (255 aa) |
| | argH | Argininosuccinate lyase (Arginosuccinase) (ASAL); Function of strongly homologous gene; enzyme. (464 aa) |
| | cyaA | Adenylate cyclase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (954 aa) |
| | lysA-2 | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (415 aa) |
| | dfp | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (403 aa) |
| | ubiC2 | Putative chorismate-pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. (185 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (360 aa) |
| | aspA | Aspartate ammonia-lyase (aspartase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (478 aa) |
| | oadA | Oxaloacetate decarboxylase, alpha subunit; Function of strongly homologous gene; enzyme. (602 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (492 aa) |
| | trpG | Anthranilate synthase component II (Glutamine amido-transferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (197 aa) |
| | trpC | Indole-3-glycerol phosphate synthase (IGPS); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TrpC family. (278 aa) |
| | ribB/A | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (363 aa) |
| | ribB | 3,4 dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (216 aa) |
| | eutC | Putative ethanolamine ammonia-lyase, light subunit EutC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the EutC family. (272 aa) |
| | eutB | Ethanolamine ammonia-lyase, heavy chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (464 aa) |
| | ubiX | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (209 aa) |
| | gudD | D-glucarate dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (451 aa) |
| | phrB | Deoxyribodipyrimidine photolyase (photoreactivation), FAD-binding; Function of strongly homologous gene; enzyme; Belongs to the DNA photolyase family. (484 aa) |
| | hemH | Ferrochelatase (Protoheme ferro-lyase); Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (337 aa) |
| | PSEEN0962 | Putative siderophore biosynthesis protein PvcA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; factor. (328 aa) |
| | PSEEN0973 | Putative Dihydrodipicolinate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the DapA family. (303 aa) |
| | PSEEN0975 | Hypothetical protein; No homology to any previously reported sequences. (340 aa) |
| | PSEEN0984 | Putative PLP-dependent decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (502 aa) |
| | PSEEN1035 | Putative ornithine decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (387 aa) |
| | rlpA | Putative lipoprotein, RplA family; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (124 aa) |
| | fumC-1 | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (458 aa) |
| | PSEEN1145 | Putative fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (507 aa) |
| | pcaB | 3-carboxy-cis,cis-muconate cycloisomerase (3-carboxymuconate lactonizing enzyme) (CMLE); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (450 aa) |
| | PSEEN1199 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (156 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (212 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (875 aa) |
| | PSEEN1269 | Putative carboxyvinyl-carboxyphosphonate phosphorylmutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (276 aa) |
| | cysM | Cysteine synthase B (O-acetylserine sulfhydrolase B); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the cysteine synthase/cystathionine beta- synthase family. (299 aa) |
| | cobD | Putative cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (302 aa) |
| | PSEEN1382 | Putative cobalamin biosynthesis protein CobC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (330 aa) |
| | fumC | Fumarase C (fumarate hydratase Class II); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa) |
| | pheA | Bifunctional chorismate mutase/prephenate dehydratase PheA; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (364 aa) |
| | pyrF | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (233 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (363 aa) |
| | PSEEN1622 | Putative 4-amino-4-deoxychorismate lyase PabC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (271 aa) |
| | mltG-2 | Conserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (380 aa) |
| | PSEEN1630 | Putative molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (322 aa) |
| | leuC | 3-isopropylmalate dehydratase (isomerase), large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (477 aa) |
| | leuD | 3-isopropylmalate isomerase (dehydratase), small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (214 aa) |
| | PSEEN1655 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (137 aa) |
| | gcl | Glyoxylate carboligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TPP enzyme family. (591 aa) |
| | allA | Ureidoglycolate hydrolase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source. (167 aa) |
| | PSEEN1684 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (171 aa) |
| | metZ | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (403 aa) |
| | rraA | Regulator of ribonuclease activity A; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity). (163 aa) |
| | arcB | Ornithine cyclodeaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (348 aa) |
| | PSEEN1880 | Putative lytic transglycosylase; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family. (468 aa) |
| | prpB | Methylisocitrate lyase PrpB; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (296 aa) |
| | PSEEN1905 | Putative aconitate hydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (862 aa) |
| | prpD | 2-methyl citrate dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (494 aa) |
| | acnB | Aconitate hydratase 2; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aconitase/IPM isomerase family. (874 aa) |
| | PSEEN1910 | Putative 6-pyruvoyl tetrahydrobiopterin synthase SscR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (118 aa) |
| | PSEEN2008 | Putative L-serine dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (305 aa) |
| | PSEEN2014 | Putative 4-hydroxyphenylpyruvate dioxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (634 aa) |
