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PSEEN2115 PSEEN2115 pck pck hemE hemE folB folB trpE trpE trpG trpG trpC trpC ribB/A ribB/A ribB ribB ubiX ubiX phrB phrB PSEEN0975 PSEEN0975 PSEEN0984 PSEEN0984 PSEEN1035 PSEEN1035 ppc ppc PSEEN1269 PSEEN1269 cobD cobD PSEEN1382 PSEEN1382 pyrF pyrF PSEEN1622 PSEEN1622 PSEEN1630 PSEEN1630 gcl gcl PSEEN1684 PSEEN1684 rraA rraA prpB prpB nspC nspC PSEEN2370 PSEEN2370 pmsA pmsA PSEEN2523 PSEEN2523 PSEEN2628 PSEEN2628 PSEEN2812 PSEEN2812 mvaB mvaB ribB/A-2 ribB/A-2 hpaG-1 hpaG-1 hpaI hpaI aceA aceA PSEEN3557 PSEEN3557 lysA-1 lysA-1 PSEEN3956 PSEEN3956 moaA moaA PSEEN4051 PSEEN4051 PSEEN4356 PSEEN4356 eda eda ubiC1 ubiC1 speA speA psd psd thiC thiC fda fda ltaE ltaE ubiD ubiD lysA-2 lysA-2 dfp dfp ubiC2 ubiC2 purK purK oadA oadA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
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PSEEN2115Putative thiamine pyrophosphate; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the TPP enzyme family. (526 aa)
pckPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (513 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (354 aa)
folBDihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (118 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (492 aa)
trpGAnthranilate synthase component II (Glutamine amido-transferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (197 aa)
trpCIndole-3-glycerol phosphate synthase (IGPS); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TrpC family. (278 aa)
ribB/A3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (363 aa)
ribB3,4 dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (216 aa)
ubiX3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (209 aa)
phrBDeoxyribodipyrimidine photolyase (photoreactivation), FAD-binding; Function of strongly homologous gene; enzyme; Belongs to the DNA photolyase family. (484 aa)
PSEEN0975Hypothetical protein; No homology to any previously reported sequences. (340 aa)
PSEEN0984Putative PLP-dependent decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (502 aa)
PSEEN1035Putative ornithine decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (387 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (875 aa)
PSEEN1269Putative carboxyvinyl-carboxyphosphonate phosphorylmutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (276 aa)
cobDPutative cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (302 aa)
PSEEN1382Putative cobalamin biosynthesis protein CobC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (330 aa)
pyrFOrotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (233 aa)
PSEEN1622Putative 4-amino-4-deoxychorismate lyase PabC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (271 aa)
PSEEN1630Putative molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (322 aa)
gclGlyoxylate carboligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TPP enzyme family. (591 aa)
PSEEN1684Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (171 aa)
rraARegulator of ribonuclease activity A; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity). (163 aa)
prpBMethylisocitrate lyase PrpB; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (296 aa)
nspCCarboxynorspermidine decarboxylase NspC; Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine; Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily. (365 aa)
PSEEN2370Putative tyrosine decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (469 aa)
pmsAHistidine decarboxylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (403 aa)
PSEEN2523Hypothetical protein; No homology to any previously reported sequences; Belongs to the UbiD family. (412 aa)
PSEEN2628Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (267 aa)
PSEEN2812Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (318 aa)
mvaBhydroxymethylglutaryl-CoA lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (299 aa)
ribB/A-23,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (370 aa)
hpaG-14-hydroxyphenylacetate degradation; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (224 aa)
hpaI2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, with PEP/pyruvate domain; Function of strongly homologous gene; enzyme; Belongs to the HpcH/HpaI aldolase family. (266 aa)
aceAIsocitrate lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (441 aa)
PSEEN3557Putative arginine/lysine/ornithine decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (746 aa)
lysA-1Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (409 aa)
PSEEN3956Putative phosphoenolpyruvate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (296 aa)
moaAPutative molybdopterin biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (334 aa)
PSEEN4051Putative dihydrodipicolinate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the DapA family. (315 aa)
PSEEN4356Putative carboxyphosphonoenolpyruvate phosphonomutase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family. (289 aa)
eda2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (224 aa)
ubiC1Putative chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. (185 aa)
speAArginine decarboxylase, PLP-binding, biosynthetic; Catalyzes the biosynthesis of agmatine from arginine. (637 aa)
psdPhosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (287 aa)
thiCHydroxymethylpyrimidine moiety synthesis in thiamin biosynthesis; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (626 aa)
fdaFructose-1,6-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa)
ltaELow-specificity L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (346 aa)
ubiD3-octaprenyl-4-hydroxybenzoate decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. (488 aa)
lysA-2Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (415 aa)
dfpPhosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (403 aa)
ubiC2Putative chorismate-pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. (185 aa)
purKPhosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (360 aa)
oadAOxaloacetate decarboxylase, alpha subunit; Function of strongly homologous gene; enzyme. (602 aa)
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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