STRINGSTRING
PSEEN3044 PSEEN3044 PSEEN3045 PSEEN3045 PSEEN3192 PSEEN3192 PSEEN3229 PSEEN3229 PSEEN3230 PSEEN3230 PSEEN3231 PSEEN3231 PSEEN3232 PSEEN3232 PSEEN3234 PSEEN3234 PSEEN3332 PSEEN3332 iscS-2 iscS-2 metH metH PSEEN3475 PSEEN3475 lysA-1 lysA-1 sucA sucA PSEEN3650 PSEEN3650 dat dat PSEEN3734 PSEEN3734 PSEEN3858 PSEEN3858 PSEEN3862 PSEEN3862 glyA-3 glyA-3 aruC aruC phhC phhC PSEEN3954 PSEEN3954 PSEEN3999 PSEEN3999 PSEEN4000 PSEEN4000 PSEEN4039 PSEEN4039 PSEEN4223 PSEEN4223 thrC thrC PSEEN4300 PSEEN4300 PSEEN4350 PSEEN4350 mdeA mdeA ilvI ilvI PSEEN4725 PSEEN4725 hemL hemL PSEEN5013 PSEEN5013 bioA bioA glgP glgP PSEEN5110 PSEEN5110 bioF bioF glyA-2 glyA-2 ilvA-2 ilvA-2 PSEEN5252 PSEEN5252 PSEEN5296 PSEEN5296 lysA-2 lysA-2 dadX dadX PSEEN5421 PSEEN5421 PSEEN5491 PSEEN5491 PSEEN5528 PSEEN5528 PSEEN5531 PSEEN5531 PSEEN5536 PSEEN5536 PSEEN1622 PSEEN1622 gcl gcl metZ metZ PSEEN1704 PSEEN1704 psvA psvA PSEEN1935 PSEEN1935 PSEEN2008 PSEEN2008 PSEEN2115 PSEEN2115 metY metY PSEEN2149 PSEEN2149 PSEEN2150 PSEEN2150 PSEEN2154 PSEEN2154 PSEEN2342 PSEEN2342 PSEEN2370 PSEEN2370 PSEEN2374 PSEEN2374 PSEEN2394 PSEEN2394 pmsA pmsA tyrB-2 tyrB-2 PSEEN2718 PSEEN2718 PSEEN2885 PSEEN2885 PSEEN2897 PSEEN2897 PSEEN2988 PSEEN2988 aspC aspC PSEEN0132 PSEEN0132 gabT gabT PSEEN0260 PSEEN0260 PSEEN0318 PSEEN0318 PSEEN0598 PSEEN0598 dxs dxs eutC eutC PSEEN0681 PSEEN0681 glyA-1 glyA-1 PSEEN0965 PSEEN0965 PSEEN0984 PSEEN0984 iscS-1 iscS-1 PSEEN1026 PSEEN1026 PSEEN1031 PSEEN1031 hisC hisC PSEEN1319 PSEEN1319 PSEEN1325 PSEEN1325 PSEEN1382 PSEEN1382 serC serC PSEEN1516 PSEEN1516 PSEEN1583 PSEEN1583 tyrB tyrB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSEEN3044Putative non-ribosomal peptide synthetase, terminal component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (4836 aa)
PSEEN3045Putative non ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (8493 aa)
PSEEN3192Putative transcriptional regulator, GntR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator. (477 aa)
PSEEN3229Putative pyoverdine sidechain peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (3931 aa)
PSEEN3230Putative pyoverdine sidechain peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (2172 aa)
PSEEN3231Putative pyoverdine sidechain peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (2604 aa)
PSEEN3232Putative pyoverdine sidechain peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (1014 aa)
PSEEN3234Putative pyoverdine sidechain peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (3088 aa)
PSEEN3332Putative non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (2112 aa)
iscS-2Cysteine desulfurase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (405 aa)
metHMethionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1235 aa)
PSEEN3475Putative 4-aminobutyrate aminotransferase, PLP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (416 aa)
lysA-1Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (409 aa)
sucA2-oxoglutarate dehydrogenase, E1 component; Function of strongly homologous gene; enzyme. (943 aa)
PSEEN3650Putative transcriptional regulator, GntR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator. (480 aa)
datDiaminobutyrate--2-oxoglutarate aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (464 aa)
PSEEN3734Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (267 aa)
PSEEN3858Putative transcriptional regulator, GntR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator. (471 aa)
PSEEN3862Threonine synthase; Function of strongly homologous gene; enzyme. (414 aa)
glyA-3Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (410 aa)
aruCSuccinylornithine transaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (406 aa)
phhCAromatic-amino-acid aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (397 aa)
PSEEN3954Aminotransferase; Function of strongly homologous gene; enzyme. (400 aa)
PSEEN3999Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (321 aa)
PSEEN4000Putative transcriptional regulator, GntR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator. (451 aa)
PSEEN4039Putative cystathionine gamma-synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (391 aa)
PSEEN4223Putative aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (397 aa)
thrCThreonine synthase; Function of strongly homologous gene; enzyme. (469 aa)
PSEEN4300Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (315 aa)
PSEEN4350Putative acetolactate synthase, large subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the TPP enzyme family. (545 aa)
mdeAMethionine gamma-lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (398 aa)
ilvIAcetolactate synthase III, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (574 aa)
PSEEN4725Aminotransferase, class I; Function of strongly homologous gene; enzyme. (390 aa)
hemLGlutamate-1-semialdehyde aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (427 aa)
PSEEN5013Putative threonine dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (325 aa)
bioA7,8-diaminopelargonic acid synthetase, PLP-dependent; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (468 aa)
glgPGlycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (821 aa)
PSEEN5110Putative acetylornithine aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (425 aa)
bioF8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (390 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa)
ilvA-2Threonine deaminase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (504 aa)
PSEEN5252Putative oxidoreductase, 2OG-Fe(II) oxygenase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (207 aa)
PSEEN5296Aminotransferase, class III; Function of strongly homologous gene; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (453 aa)
lysA-2Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (415 aa)
dadXAlanine racemase 2, PLP-binding, catabolic; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (357 aa)
PSEEN5421Putative transcriptional regulator, GntR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator. (496 aa)
PSEEN5491Putative transcriptional regulator, GntR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator. (508 aa)
PSEEN5528Putative polyketide synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (1217 aa)
PSEEN5531Putative polyketide synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (668 aa)
PSEEN5536Putative polyketide synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (920 aa)
PSEEN1622Putative 4-amino-4-deoxychorismate lyase PabC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (271 aa)
gclGlyoxylate carboligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TPP enzyme family. (591 aa)
metZO-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (403 aa)
PSEEN1704Putative 1-aminocyclopropane-1-carboxylate deaminase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (297 aa)
psvAPyoverdine synthetase A; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (4315 aa)
PSEEN1935Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (232 aa)
PSEEN2008Putative L-serine dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (305 aa)
PSEEN2115Putative thiamine pyrophosphate; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the TPP enzyme family. (526 aa)
metYO-acetylhomoserine sulfhydrylase; Function of strongly homologous gene; enzyme. (425 aa)
PSEEN2149Putative non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (1316 aa)
PSEEN2150Putative non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (1082 aa)
PSEEN2154Putative non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (3135 aa)
PSEEN2342Putative non-ribosomal peptide synthetase, terminal component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (1292 aa)
PSEEN2370Putative tyrosine decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (469 aa)
PSEEN2374Putative transcriptional regulator (GntR family); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator. (478 aa)
PSEEN2394Putative transcriptional regulator, GntR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator. (474 aa)
pmsAHistidine decarboxylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (403 aa)
tyrB-2Aromatic amino acid aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (398 aa)
PSEEN2718Putative Polyketide Synthase (terminal component); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (3010 aa)
PSEEN2885Aminotransferase, class III; Function of strongly homologous gene; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (460 aa)
PSEEN2897Putative bifunctional: transcriptional regulator (MocR family) (N-terminal); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator. (464 aa)
PSEEN2988Putative transcriptional regulator, GntR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator. (469 aa)
aspCAspartate aminotransferase; Function of strongly homologous gene; enzyme. (409 aa)
PSEEN0132Putative non ribosomal peptide synthethase, loading module; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the ATP-dependent AMP-binding enzyme family. (1143 aa)
gabT4-aminobutyrate aminotransferase, PLP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (425 aa)
PSEEN0260Putative aminotransferase, class III; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (966 aa)
PSEEN0318Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (228 aa)
PSEEN0598Putative periplasmic cobalamin-binding protein HutB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; transporter. (270 aa)
dxs1-deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (631 aa)
eutCPutative ethanolamine ammonia-lyase, light subunit EutC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the EutC family. (272 aa)
PSEEN0681Beta-alanine--pyruvate transaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (448 aa)
glyA-1Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa)
PSEEN0965Putative aminotransferase (transaminase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (402 aa)
PSEEN0984Putative PLP-dependent decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (502 aa)
iscS-1Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. (404 aa)
PSEEN1026Putative aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (382 aa)
PSEEN1031Putative PKHD-type hydroxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (226 aa)
hisCHistidinol-phosphate aminotransferase; Function of strongly homologous gene; enzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (348 aa)
PSEEN1319Putative acetolactate synthase, catabolic; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the TPP enzyme family. (547 aa)
PSEEN1325Putative transcriptional regulator, GntR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator. (472 aa)
PSEEN1382Putative cobalamin biosynthesis protein CobC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (330 aa)
serC3-phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (361 aa)
PSEEN1516Putative transcriptional regulator, GntR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator. (465 aa)
PSEEN1583Putative aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (403 aa)
tyrBAromatic-amino-acid aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (398 aa)
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.