(70 nodes) Glyoxylate and dicarboxylate metabolism network (Botryotinia calthae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A4Y8CDI4	PNPLA domain-containing protein. (335 aa)
	A0A4Y8CIQ5	Uncharacterized protein. (640 aa)
	A0A4Y8CIR7	Uncharacterized protein. (370 aa)
	A0A4Y8CJU2	2-Hacid_dh_C domain-containing protein. (237 aa)
	A0A4Y8CJX8	Uncharacterized protein. (366 aa)
	A0A4Y8CL51	Uncharacterized protein. (415 aa)
	A0A4Y8CL69	Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (863 aa)
	A0A4Y8CMD2	CoA carboxyltransferase C-terminal domain-containing protein. (580 aa)
	A0A4Y8CMF9	Uncharacterized protein. (294 aa)
	A0A4Y8CP79	Uncharacterized protein. (504 aa)
	A0A4Y8CRG2	Uncharacterized protein. (379 aa)
	A0A4Y8CS34	Citrate synthase; Belongs to the citrate synthase family. (473 aa)
	A0A4Y8CS68	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (563 aa)
	A0A4Y8CS79	Isocitrate lyase. (509 aa)
	A0A4Y8CSH3	Catalase domain-containing protein. (541 aa)
	A0A4Y8CSK1	Glutamine synthetase. (368 aa)
	A0A4Y8CTC0	Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (498 aa)
	A0A4Y8CUT0	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1073 aa)
	A0A4Y8CVC2	Uncharacterized protein. (320 aa)
	A0A4Y8CVS3	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
	A0A4Y8CVY6	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (475 aa)
	A0A4Y8CW44	Malate dehydrogenase. (341 aa)
	A0A4Y8CWQ3	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (345 aa)
	A0A4Y8CWV2	MFS domain-containing protein. (595 aa)
	A0A4Y8CX65	Malate dehydrogenase. (332 aa)
	A0A4Y8CXF1	MFS domain-containing protein. (153 aa)
	A0A4Y8CXU6	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family. (737 aa)
	A0A4Y8CYP2	Uncharacterized protein; Belongs to the DapA family. (321 aa)
	A0A4Y8CZ94	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (434 aa)
	A0A4Y8CZA5	Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (437 aa)
	A0A4Y8CZK6	Fe2OG dioxygenase domain-containing protein. (829 aa)
	A0A4Y8D011	Malate synthase; Belongs to the malate synthase family. (440 aa)
	A0A4Y8D0G3	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (389 aa)
	A0A4Y8D0N3	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (331 aa)
	A0A4Y8D1M3	ACT domain-containing protein. (294 aa)
	A0A4Y8D1Q9	Catalase domain-containing protein. (315 aa)
	A0A4Y8D309	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (313 aa)
	A0A4Y8D3N9	Acetyl-coenzyme A synthetase. (668 aa)
	A0A4Y8D3S4	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family. (714 aa)
	A0A4Y8D400	Catalase domain-containing protein. (501 aa)
	A0A4Y8D4V5	FAD_binding_3 domain-containing protein. (520 aa)
	A0A4Y8D5I5	AAA domain-containing protein; Belongs to the AAA ATPase family. (419 aa)
	A0A4Y8D5I8	Isocitrate lyase. (548 aa)
	A0A4Y8D5R0	MFS domain-containing protein. (635 aa)
	A0A4Y8D6H4	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (521 aa)
	A0A4Y8D7A6	SET domain-containing protein. (377 aa)
	A0A4Y8D811	MFS domain-containing protein. (554 aa)
	A0A4Y8D8T3	Uncharacterized protein. (644 aa)
	A0A4Y8D8V5	Uncharacterized protein. (520 aa)
	A0A4Y8D8X1	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (359 aa)
	A0A4Y8D9I1	PNPLA domain-containing protein. (116 aa)
	A0A4Y8D9J1	PNPLA domain-containing protein. (631 aa)
	A0A4Y8DAA5	Zn(2)-C6 fungal-type domain-containing protein. (1011 aa)
	A0A4Y8DB82	Aminotran_5 domain-containing protein. (385 aa)
	A0A4Y8DBH3	AB hydrolase-1 domain-containing protein. (259 aa)
	A0A4Y8DDA3	Zn(2)-C6 fungal-type domain-containing protein. (705 aa)
	A0A4Y8DDL8	SET domain-containing protein. (498 aa)
	A0A4Y8DE14	Uncharacterized protein. (318 aa)
	A0A4Y8DEI1	Uncharacterized protein. (342 aa)
	A0A4Y8DEW9	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (477 aa)
	A0A4Y8DFG9	Uncharacterized protein. (455 aa)
	A0A4Y8DFP9	Citrate synthase; Belongs to the citrate synthase family. (472 aa)
	A0A4Y8DG79	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (173 aa)
	A0A4Y8DGE3	Uncharacterized protein. (513 aa)
	A0A4Y8DGF5	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (502 aa)
	A0A4Y8DGU9	Uncharacterized protein. (450 aa)
	A0A4Y8DHK5	MFS domain-containing protein. (473 aa)
	A0A4Y8DHV6	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (783 aa)
	A0A4Y8DI23	Dihydrolipoyl dehydrogenase. (510 aa)
	A0A4Y8DJ82	AAA domain-containing protein. (901 aa)

Your Current Organism:

Botryotinia calthae

NCBI taxonomy Id: 38488
Other names: B. calthae, Botrytis calthae, Botrytis calthae Hennebert

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A4Y8CIQ5	A0A4Y8CJU2	Uncharacterized protein.	2-Hacid_dh_C domain-containing protein.	0.520
A0A4Y8CIQ5	A0A4Y8CJX8	Uncharacterized protein.	Uncharacterized protein.	0.445
A0A4Y8CIQ5	A0A4Y8CS79	Uncharacterized protein.	Isocitrate lyase.	0.747
A0A4Y8CIQ5	A0A4Y8CWQ3	Uncharacterized protein.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.520
A0A4Y8CIQ5	A0A4Y8CZA5	Uncharacterized protein.	Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	0.417
A0A4Y8CIQ5	A0A4Y8CZK6	Uncharacterized protein.	Fe2OG dioxygenase domain-containing protein.	0.445
A0A4Y8CIQ5	A0A4Y8D011	Uncharacterized protein.	Malate synthase; Belongs to the malate synthase family.	0.801
A0A4Y8CIQ5	A0A4Y8D0G3	Uncharacterized protein.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.445
A0A4Y8CIQ5	A0A4Y8D0N3	Uncharacterized protein.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.445
A0A4Y8CIQ5	A0A4Y8D5I8	Uncharacterized protein.	Isocitrate lyase.	0.747
A0A4Y8CIQ5	A0A4Y8D8X1	Uncharacterized protein.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.417
A0A4Y8CIQ5	A0A4Y8DB82	Uncharacterized protein.	Aminotran_5 domain-containing protein.	0.821
A0A4Y8CJU2	A0A4Y8CIQ5	2-Hacid_dh_C domain-containing protein.	Uncharacterized protein.	0.520
A0A4Y8CJU2	A0A4Y8CJX8	2-Hacid_dh_C domain-containing protein.	Uncharacterized protein.	0.493
A0A4Y8CJU2	A0A4Y8CMD2	2-Hacid_dh_C domain-containing protein.	CoA carboxyltransferase C-terminal domain-containing protein.	0.461
A0A4Y8CJU2	A0A4Y8CMF9	2-Hacid_dh_C domain-containing protein.	Uncharacterized protein.	0.633
A0A4Y8CJU2	A0A4Y8CRG2	2-Hacid_dh_C domain-containing protein.	Uncharacterized protein.	0.896
A0A4Y8CJU2	A0A4Y8CS34	2-Hacid_dh_C domain-containing protein.	Citrate synthase; Belongs to the citrate synthase family.	0.468
A0A4Y8CJU2	A0A4Y8CS79	2-Hacid_dh_C domain-containing protein.	Isocitrate lyase.	0.896
A0A4Y8CJU2	A0A4Y8CUT0	2-Hacid_dh_C domain-containing protein.	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.	0.714