(27 nodes) Butanoate metabolism network (Botryotinia calthae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:
	A0A4Y8D5I1	Succinate-semialdehyde dehydrogenase. (530 aa)
	A0A4Y8DGQ0	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (457 aa)
	A0A4Y8DFK1	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (557 aa)
	A0A4Y8DEY2	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (555 aa)
	A0A4Y8DER3	Acetolactate synthase. (699 aa)
	A0A4Y8DEM2	Uncharacterized protein. (318 aa)
	A0A4Y8DCL2	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (288 aa)
	A0A4Y8DBE4	AMP-binding domain-containing protein. (615 aa)
	A0A4Y8DAC3	Pyruvate carboxyltransferase domain-containing protein. (375 aa)
	A0A4Y8D8V5	Uncharacterized protein. (520 aa)
	A0A4Y8CJF2	Uncharacterized protein. (451 aa)
	A0A4Y8CJN7	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (455 aa)
	A0A4Y8CKC7	Aldedh domain-containing protein. (498 aa)
	A0A4Y8CL28	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (518 aa)
	A0A4Y8CP73	Uncharacterized protein. (692 aa)
	A0A4Y8CRS0	Uncharacterized protein. (294 aa)
	A0A4Y8CS12	ACT domain-containing protein. (323 aa)
	A0A4Y8CS58	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (467 aa)
	A0A4Y8CV92	DAO domain-containing protein. (514 aa)
	A0A4Y8CVS3	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
	A0A4Y8CW38	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (481 aa)
	A0A4Y8CXT8	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (459 aa)
	A0A4Y8CZ86	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (307 aa)
	A0A4Y8CZ94	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (434 aa)
	A0A4Y8D0Q0	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (494 aa)
	A0A4Y8D1D0	DAO domain-containing protein. (409 aa)
	A0A4Y8D490	Uncharacterized protein. (552 aa)

Your Current Organism:

Botryotinia calthae

NCBI taxonomy Id: 38488
Other names: B. calthae, Botrytis calthae, Botrytis calthae Hennebert

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A4Y8CJF2	A0A4Y8CKC7	Uncharacterized protein.	Aldedh domain-containing protein.	0.550
A0A4Y8CJF2	A0A4Y8CV92	Uncharacterized protein.	DAO domain-containing protein.	0.401
A0A4Y8CJF2	A0A4Y8CW38	Uncharacterized protein.	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	0.735
A0A4Y8CJF2	A0A4Y8D0Q0	Uncharacterized protein.	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.834
A0A4Y8CJF2	A0A4Y8D1D0	Uncharacterized protein.	DAO domain-containing protein.	0.401
A0A4Y8CJF2	A0A4Y8D5I1	Uncharacterized protein.	Succinate-semialdehyde dehydrogenase.	0.550
A0A4Y8CJF2	A0A4Y8DFK1	Uncharacterized protein.	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	0.723
A0A4Y8CJF2	A0A4Y8DGQ0	Uncharacterized protein.	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.547
A0A4Y8CJN7	A0A4Y8CL28	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.916
A0A4Y8CJN7	A0A4Y8CP73	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein.	0.602
A0A4Y8CJN7	A0A4Y8CVS3	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.985
A0A4Y8CJN7	A0A4Y8CXT8	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.898
A0A4Y8CJN7	A0A4Y8CZ94	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.980
A0A4Y8CJN7	A0A4Y8D490	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein.	0.494
A0A4Y8CJN7	A0A4Y8D8V5	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein.	0.911
A0A4Y8CJN7	A0A4Y8DAC3	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Pyruvate carboxyltransferase domain-containing protein.	0.933
A0A4Y8CJN7	A0A4Y8DBE4	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	AMP-binding domain-containing protein.	0.602
A0A4Y8CJN7	A0A4Y8DCL2	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.531
A0A4Y8CJN7	A0A4Y8DEM2	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein.	0.897
A0A4Y8CJN7	A0A4Y8DEY2	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.916