STRINGSTRING
WNT11 WNT11 WIF1 WIF1 WNT3 WNT3 SOST SOST SFRP1 SFRP1 WNT5B WNT5B SFRP2 SFRP2 WNT2 WNT2 DKK4 DKK4 WNT3A WNT3A SFRP5 SFRP5 GPC4 GPC4 LRP6 LRP6 DKK3 DKK3 FZD3 FZD3 CER1 CER1 LOC102367890 LOC102367890 WNT1 WNT1 LOC102380960 LOC102380960 WNT6 WNT6 FZD2 FZD2 ROR2 ROR2 FZD7 FZD7 WNT4 WNT4 FZD5 FZD5 SFRP4 SFRP4 WNT2B WNT2B FZD10 FZD10 ROR1 ROR1 WNT16 WNT16 NOTUM NOTUM LOC102367925 LOC102367925 WNT10A WNT10A WNT9B WNT9B WNT5A WNT5A LRP5 LRP5 RYK RYK WNT8A WNT8A LOC102385203 LOC102385203 FZD6 FZD6 FZD1 FZD1 FZD9 FZD9 WNT9A WNT9A WLS WLS PORCN PORCN DKK2 DKK2 FZD4 FZD4 WNT8B WNT8B LOC102383312 LOC102383312
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
WIF1Wnt inhibitory factor 1. (343 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
SOSTLOW QUALITY PROTEIN: sclerostin. (210 aa)
SFRP1Secreted frizzled-related protein 1. (331 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (260 aa)
SFRP2Secreted frizzled-related protein 2. (294 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
DKK4Dickkopf-related protein 4. (219 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
SFRP5Secreted frizzled-related protein 5. (400 aa)
GPC4Glypican-4 isoform X1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (601 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1604 aa)
DKK3Dickkopf-related protein 3. (290 aa)
FZD3LOW QUALITY PROTEIN: frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (670 aa)
CER1Cerberus isoform X1. (274 aa)
LOC102367890Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (348 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (341 aa)
LOC102380960Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (342 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (435 aa)
FZD2LOW QUALITY PROTEIN: frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (635 aa)
ROR2LOW QUALITY PROTEIN: tyrosine-protein kinase transmembrane receptor ROR2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (913 aa)
FZD7LOW QUALITY PROTEIN: frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (323 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (296 aa)
FZD5LOW QUALITY PROTEIN: frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (510 aa)
SFRP4Secreted frizzled-related protein 4. (211 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (299 aa)
FZD10Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (494 aa)
ROR1LOW QUALITY PROTEIN: inactive tyrosine-protein kinase transmembrane receptor ROR1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (885 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (257 aa)
NOTUMPalmitoleoyl-protein carboxylesterase NOTUM. (458 aa)
LOC102367925Secreted frizzled-related protein 2-like. (287 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (413 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (377 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1593 aa)
RYKTyrosine-protein kinase RYK. (600 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
LOC102385203Palmitoleoyl-protein carboxylesterase notum2-like isoform X1. (480 aa)
FZD6Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family. (667 aa)
FZD1LOW QUALITY PROTEIN: frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (405 aa)
FZD9LOW QUALITY PROTEIN: frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (538 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
WLSProtein wntless homolog isoform X1. (478 aa)
PORCNProtein-serine O-palmitoleoyltransferase porcupine isoform X1; Belongs to the membrane-bound acyltransferase family. (587 aa)
DKK2Dickkopf-related protein 2. (269 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (450 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa)
LOC102383312Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (338 aa)
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
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