STRINGSTRING
DLL4 DLL4 APOH APOH TNMD TNMD CAV3 CAV3 PDCD10 PDCD10 TBC1D31 TBC1D31 GHRL GHRL LOC102377648 LOC102377648 AIMP1 AIMP1 ATP5F1A ATP5F1A KRIT1 KRIT1 LOC102378738 LOC102378738 IL12A IL12A RGCC RGCC THBS1 THBS1 TGFBR1 TGFBR1 VASH1 VASH1 CAV1 CAV1 CAV2 CAV2 FLT1 FLT1 NF1 NF1 MMRN2 MMRN2 ACVRL1 ACVRL1 LOC102368462 LOC102368462 SULF1 SULF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (615 aa)
APOHBeta-2-glycoprotein 1. (350 aa)
TNMDTenomodulin isoform X2. (318 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
PDCD10Programmed cell death protein 10 isoform X1. (212 aa)
TBC1D31TBC1 domain family member 31. (1091 aa)
GHRLAppetite-regulating hormone isoform X1. (145 aa)
LOC102377648Synaptojanin-2-binding protein. (145 aa)
AIMP1Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 isoform X2. (319 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (566 aa)
KRIT1Krev interaction trapped protein 1 isoform X1. (736 aa)
LOC102378738Tumor necrosis factor. (231 aa)
IL12AInterleukin-12 subunit alpha; Belongs to the IL-6 superfamily. (145 aa)
RGCCRegulator of cell cycle RGCC. (131 aa)
THBS1Thrombospondin-1 isoform X1. (1213 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (440 aa)
VASH1Vasohibin-1. (347 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (128 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
FLT1Vascular endothelial growth factor receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1238 aa)
NF1Neurofibromin. (2861 aa)
MMRN2LOW QUALITY PROTEIN: multimerin-2. (1011 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (523 aa)
LOC102368462Vascular endothelial growth factor receptor kdr-like; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1336 aa)
SULF1Extracellular sulfatase Sulf-1 isoform X1. (1125 aa)
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
Server load: low (18%) [HD]