55 items (Alligator sinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102369239	Nuclear receptor subfamily 2 group F member 5. (341 aa)
	NR1H3	LOW QUALITY PROTEIN: oxysterols receptor LXR-alpha. (414 aa)
	ESRRB	Steroid hormone receptor ERR2 isoform X1. (451 aa)
	NR4A3	Nuclear receptor subfamily 4 group A member 3. (613 aa)
	NR1H2	Oxysterols receptor LXR-beta isoform X1. (438 aa)
	HNF4A	Hepatocyte nuclear factor 4-alpha isoform X1. (467 aa)
	RARB	Retinoic acid receptor beta isoform X1. (455 aa)
	AHRR	Aryl hydrocarbon receptor repressor. (754 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (475 aa)
	SMDT1	Essential MCU regulator, mitochondrial. (98 aa)
	THRB	Thyroid hormone receptor beta isoform X1. (391 aa)
	NR2F2	COUP transcription factor 2 isoform X1. (418 aa)
	LOC102381188	Bile acid receptor-like isoform X1. (510 aa)
	NR4A1	Nuclear receptor subfamily 4 group A member 1. (579 aa)
	NKX3-1	Homeobox protein Nkx-3.1 isoform X1. (232 aa)
	RORB	Nuclear receptor ROR-beta. (461 aa)
	RXRA	Retinoic acid receptor RXR-alpha isoform X2. (486 aa)
	LOC102381098	Estrogen-related receptor gamma isoform X2. (458 aa)
	PPARA	Peroxisome proliferator-activated receptor alpha isoform X1. (468 aa)
	NR2E3	Photoreceptor-specific nuclear receptor. (414 aa)
	NR1D2	Nuclear receptor subfamily 1 group D member 2 isoform X2. (588 aa)
	LOC102377330	Hepatocyte nuclear factor 4-beta-like. (457 aa)
	PPARD	Peroxisome proliferator-activated receptor delta isoform X1. (442 aa)
	ESR2	Estrogen receptor beta isoform X1. (548 aa)
	LOC102384928	Aryl hydrocarbon receptor-like. (1015 aa)
	RARA	Retinoic acid receptor alpha isoform X1. (473 aa)
	NR1H4	Bile acid receptor. (465 aa)
	NR5A1	Steroidogenic factor 1. (480 aa)
	RORC	Nuclear receptor ROR-gamma isoform X1. (542 aa)
	NR6A1	Nuclear receptor subfamily 6 group A member 1 isoform X1. (538 aa)
	NR1I3	Nuclear receptor subfamily 1 group I member 3 isoform X1. (431 aa)
	LOC102371615	Steroid hormone receptor ERR1. (198 aa)
	RXRG	Retinoic acid receptor RXR-gamma isoform X1. (452 aa)
	NR2F6	Nuclear receptor subfamily 2 group F member 6 isoform X1. (502 aa)
	AHR	LOW QUALITY PROTEIN: aryl hydrocarbon receptor. (731 aa)
	AR	Androgen receptor isoform X2. (430 aa)
	LOC102381221	Aryl hydrocarbon receptor-like isoform X1. (1134 aa)
	RORA	Nuclear receptor ROR-alpha. (472 aa)
	HNF4G	LOW QUALITY PROTEIN: hepatocyte nuclear factor 4-gamma. (454 aa)
	NR3C1	Glucocorticoid receptor isoform X1. (807 aa)
	NR1D1	Nuclear receptor subfamily 1 group D member 1 isoform X1. (637 aa)
	THRA	Thyroid hormone receptor alpha isoform X1. (429 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (627 aa)
	NR2C2	Nuclear receptor subfamily 2 group C member 2. (629 aa)
	NR5A2	Nuclear receptor subfamily 5 group A member 2 isoform X1. (469 aa)
	NR4A2	Nuclear receptor subfamily 4 group A member 2. (606 aa)
	LOC102387451	Nuclear receptor subfamily 2 group F member 1-A. (260 aa)
	STAT3	Signal transducer and activator of transcription. (771 aa)
	LOC102373234	Nuclear receptor ROR-beta-like isoform X1. (467 aa)
	PGR	Progesterone receptor. (338 aa)
	VDR	Vitamin D3 receptor. (520 aa)
	LOC102377832	Nuclear receptor subfamily 1 group D member 1-like. (516 aa)
	NR2E1	Nuclear receptor subfamily 2 group E member 1. (586 aa)
	RARG	LOW QUALITY PROTEIN: retinoic acid receptor gamma. (387 aa)
	RXRB	Retinoic acid receptor RXR-beta. (435 aa)

Your Current Organism:

Alligator sinensis

NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHR	ESR1	A0A3Q0G3J1	A0A3Q0GNM7	LOW QUALITY PROTEIN: aryl hydrocarbon receptor.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.418
AR	ESR1	A0A3Q0G8Z2	A0A3Q0GNM7	Androgen receptor isoform X2.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.701
AR	ESR2	A0A3Q0G8Z2	A0A1U8D748	Androgen receptor isoform X2.	Estrogen receptor beta isoform X1.	0.406
AR	NKX3-1	A0A3Q0G8Z2	A0A1U7SB75	Androgen receptor isoform X2.	Homeobox protein Nkx-3.1 isoform X1.	0.592
AR	NR3C1	A0A3Q0G8Z2	A0A3Q0GJE3	Androgen receptor isoform X2.	Glucocorticoid receptor isoform X1.	0.645
AR	PGR	A0A3Q0G8Z2	A0A3Q0H404	Androgen receptor isoform X2.	Progesterone receptor.	0.656
AR	STAT3	A0A3Q0G8Z2	A0A3Q0GY41	Androgen receptor isoform X2.	Signal transducer and activator of transcription.	0.566
ESR1	AHR	A0A3Q0GNM7	A0A3Q0G3J1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	LOW QUALITY PROTEIN: aryl hydrocarbon receptor.	0.418
ESR1	AR	A0A3Q0GNM7	A0A3Q0G8Z2	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Androgen receptor isoform X2.	0.701
ESR1	ESR2	A0A3Q0GNM7	A0A1U8D748	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Estrogen receptor beta isoform X1.	0.935
ESR1	LOC102381221	A0A3Q0GNM7	A0A3Q0G9M6	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Aryl hydrocarbon receptor-like isoform X1.	0.426
ESR1	LOC102384928	A0A3Q0GNM7	A0A1U8D7K4	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Aryl hydrocarbon receptor-like.	0.418
ESR1	NR3C1	A0A3Q0GNM7	A0A3Q0GJE3	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Glucocorticoid receptor isoform X1.	0.508
ESR1	NR5A1	A0A3Q0GNM7	A0A1U8DLF0	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Steroidogenic factor 1.	0.484
ESR1	NR5A2	A0A3Q0GNM7	A0A3Q0GRS7	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Nuclear receptor subfamily 5 group A member 2 isoform X1.	0.482
ESR1	PGR	A0A3Q0GNM7	A0A3Q0H404	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Progesterone receptor.	0.940
ESR1	PPARG	A0A3Q0GNM7	A0A1U7RQ42	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.529
ESR1	STAT3	A0A3Q0GNM7	A0A3Q0GY41	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Signal transducer and activator of transcription.	0.610
ESR2	AR	A0A1U8D748	A0A3Q0G8Z2	Estrogen receptor beta isoform X1.	Androgen receptor isoform X2.	0.406
ESR2	ESR1	A0A1U8D748	A0A3Q0GNM7	Estrogen receptor beta isoform X1.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.935