42 items (Alligator sinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GSK3A	Glycogen synthase kinase-3 alpha. (298 aa)
	SLC37A4	Glucose-6-phosphate exchanger SLC37A4 isoform X1. (435 aa)
	ACADM	Medium-chain specific acyl-CoA dehydrogenase, mitochondrial. (419 aa)
	PPP1R3B	Protein phosphatase 1 regulatory subunit 3B isoform X1. (301 aa)
	PPP1R3C	Protein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (315 aa)
	STK40	Serine/threonine-protein kinase 40. (435 aa)
	GYS2	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (725 aa)
	LOC106723050	General transcription factor II-I repeat domain-containing protein 2B-like. (719 aa)
	PCDH12	Protocadherin-12 isoform X1. (1153 aa)
	PPP1R1A	Protein phosphatase 1 regulatory subunit 1A. (129 aa)
	GBE1	1,4-alpha-glucan-branching enzyme. (592 aa)
	STBD1	Starch-binding domain-containing protein 1. (282 aa)
	GSK3B	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (409 aa)
	UGP2	UTP--glucose-1-phosphate uridylyltransferase. (523 aa)
	LOC102377068	General transcription factor II-I repeat domain-containing protein 2A-like. (435 aa)
	LOC106723017	1,4-alpha-glucan-branching enzyme-like. (100 aa)
	PHKG2	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform. (331 aa)
	LOC102380800	General transcription factor II-I repeat domain-containing protein 2A-like. (538 aa)
	GYS1	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (617 aa)
	PHKA2	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1244 aa)
	NR1D1	Nuclear receptor subfamily 1 group D member 1 isoform X1. (637 aa)
	EPM2A	Laforin. (192 aa)
	RB1CC1	RB1-inducible coiled-coil protein 1 isoform X1. (1618 aa)
	PHKA1	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1299 aa)
	CRLF1	Cytokine receptor-like factor 1. (410 aa)
	LEPR	Leptin receptor isoform X1. (1156 aa)
	LOC102372584	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (1316 aa)
	GYG1	Glycogenin-1. (264 aa)
	PPP1CB	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (326 aa)
	PPP1CC	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (323 aa)
	AGL	Glycogen debranching enzyme isoform X1. (1531 aa)
	PPP1R3D	Protein phosphatase 1 regulatory subunit 3D. (202 aa)
	PPP1R3A	Protein phosphatase 1 regulatory subunit 3A. (1235 aa)
	PYGB	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (839 aa)
	PYGL	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (864 aa)
	IL6ST	Interleukin-6 receptor subunit beta. (919 aa)
	NHLRC1	E3 ubiquitin-protein ligase NHLRC1. (400 aa)
	LOC102371924	General transcription factor II-I repeat domain-containing protein 2-like. (663 aa)
	PPP1CA	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (301 aa)
	PHKB	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1090 aa)
	PHKG1	Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform; Belongs to the protein kinase superfamily. (388 aa)
	PPP1R3E	Protein phosphatase 1 regulatory subunit 3E. (305 aa)

Your Current Organism:

Alligator sinensis

NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGL	EPM2A	A0A1U7RIN6	A0A3Q0GLP3	Glycogen debranching enzyme isoform X1.	Laforin.	0.545
AGL	GBE1	A0A1U7RIN6	A0A1U8DX83	Glycogen debranching enzyme isoform X1.	1,4-alpha-glucan-branching enzyme.	0.976
AGL	GYG1	A0A1U7RIN6	A0A3Q0HFS5	Glycogen debranching enzyme isoform X1.	Glycogenin-1.	0.975
AGL	GYS1	A0A1U7RIN6	A0A3Q0G169	Glycogen debranching enzyme isoform X1.	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	0.826
AGL	GYS2	A0A1U7RIN6	A0A1U8DHE6	Glycogen debranching enzyme isoform X1.	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	0.826
AGL	LOC102372584	A0A1U7RIN6	A0A3Q0HFG4	Glycogen debranching enzyme isoform X1.	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	0.991
AGL	LOC106723017	A0A1U7RIN6	A0A3Q0FRG5	Glycogen debranching enzyme isoform X1.	1,4-alpha-glucan-branching enzyme-like.	0.772
AGL	NHLRC1	A0A1U7RIN6	A0A1U7S0W5	Glycogen debranching enzyme isoform X1.	E3 ubiquitin-protein ligase NHLRC1.	0.565
AGL	PYGB	A0A1U7RIN6	A0A1U7RRK1	Glycogen debranching enzyme isoform X1.	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	0.994
AGL	PYGL	A0A1U7RIN6	A0A1U7RSA6	Glycogen debranching enzyme isoform X1.	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	0.994
AGL	STBD1	A0A1U7RIN6	A0A3Q0FKM1	Glycogen debranching enzyme isoform X1.	Starch-binding domain-containing protein 1.	0.548
AGL	UGP2	A0A1U7RIN6	A0A3Q0FPN6	Glycogen debranching enzyme isoform X1.	UTP--glucose-1-phosphate uridylyltransferase.	0.957
EPM2A	AGL	A0A3Q0GLP3	A0A1U7RIN6	Laforin.	Glycogen debranching enzyme isoform X1.	0.545
EPM2A	GYS1	A0A3Q0GLP3	A0A3Q0G169	Laforin.	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	0.450
EPM2A	GYS2	A0A3Q0GLP3	A0A1U8DHE6	Laforin.	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	0.450
EPM2A	NHLRC1	A0A3Q0GLP3	A0A1U7S0W5	Laforin.	E3 ubiquitin-protein ligase NHLRC1.	0.910
EPM2A	STBD1	A0A3Q0GLP3	A0A3Q0FKM1	Laforin.	Starch-binding domain-containing protein 1.	0.664
GBE1	AGL	A0A1U8DX83	A0A1U7RIN6	1,4-alpha-glucan-branching enzyme.	Glycogen debranching enzyme isoform X1.	0.976
GBE1	GYG1	A0A1U8DX83	A0A3Q0HFS5	1,4-alpha-glucan-branching enzyme.	Glycogenin-1.	0.988
GBE1	GYS1	A0A1U8DX83	A0A3Q0G169	1,4-alpha-glucan-branching enzyme.	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	0.990