STRINGSTRING
CRY2 CRY2 KDM8 KDM8 DBP DBP LOC102378300 LOC102378300 PPARGC1A PPARGC1A OGT OGT RAI1 RAI1 PML PML LOC102370063 LOC102370063 LOC102385821 LOC102385821 CRY1 CRY1 LOC102383432 LOC102383432 SIRT1 SIRT1 LOC102375552 LOC102375552 LOC102382870 LOC102382870 LOC102378535 LOC102378535 NRIP1 NRIP1 BHLHE40 BHLHE40 LOC102372380 LOC102372380 MTTP MTTP ZPBP2 ZPBP2 CSNK1E CSNK1E METTL3 METTL3 ATF4 ATF4 DRD2 DRD2 PPP1CA PPP1CA EGR3 EGR3 LOC102372737 LOC102372737 CREB1 CREB1 MYBBP1A MYBBP1A HDAC3 HDAC3 PPARA PPARA NFIL3 NFIL3 THRAP3 THRAP3 ATOH7 ATOH7 LOC102382695 LOC102382695 CSNK1D CSNK1D PROK2 PROK2 NR1D2 NR1D2 LOC102372634 LOC102372634 LOC106722193 LOC106722193 ID2 ID2 LOC102384928 LOC102384928 EP300 EP300 HTR7 HTR7 HUWE1 HUWE1 NPAS2 NPAS2 PRMT5 PRMT5 TIMELESS TIMELESS RORC RORC TOP1 TOP1 GPR157 GPR157 ARNTL ARNTL CIART CIART LOC112548358 LOC112548358 TP53 TP53 PER1 PER1 SIRT6 SIRT6 NAGLU NAGLU AHR AHR BTBD9 BTBD9 GPR176 GPR176 CLOCK CLOCK LOC102372873 LOC102372873 LGR4 LGR4 LOC102381221 LOC102381221 RORA RORA HOMER1 HOMER1 CUNH3orf70 CUNH3orf70 NGFR NGFR NR1D1 NR1D1 NUDT12 NUDT12 LOC102382509 LOC102382509 NMS NMS NOCT NOCT PPP1CC PPP1CC CARTPT CARTPT AANAT AANAT EGR2 EGR2 NR0B2 NR0B2 MC3R MC3R PAX4 PAX4 MYCBP2 MYCBP2 PPP1CB PPP1CB LOC102381255 LOC102381255 BHLHE41 BHLHE41 PER3 PER3 NTRK1 NTRK1 SETX SETX TNFRSF11A TNFRSF11A LOC102377832 LOC102377832 ATF5 ATF5 HNF1B HNF1B NDUFA9 NDUFA9 KLF10 KLF10 NAMPT NAMPT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CRY2Cryptochrome-2. (547 aa)
KDM8jmjC domain-containing protein 5. (268 aa)
DBPD site-binding protein isoform X1. (434 aa)
LOC102378300Tumor necrosis factor receptor superfamily member 16-like. (384 aa)
PPARGC1APeroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1. (810 aa)
OGTUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit. (930 aa)
RAI1LOW QUALITY PROTEIN: retinoic acid-induced protein 1. (1935 aa)
PMLProtein PML. (586 aa)
LOC1023700635-hydroxytryptamine receptor 7-like; Belongs to the G-protein coupled receptor 1 family. (426 aa)
LOC102385821Tyrosine-protein kinase receptor. (363 aa)
CRY1Cryptochrome-1. (620 aa)
LOC102383432Lysine-specific demethylase 5A. (767 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X1. (557 aa)
LOC102375552Lysine-specific demethylase 5A-like. (867 aa)
LOC102382870Cryptochrome-1-like. (530 aa)
LOC102378535Protein PML-like isoform X1. (852 aa)
NRIP1Nuclear receptor-interacting protein 1. (1162 aa)
BHLHE40Class E basic helix-loop-helix protein 40. (388 aa)
LOC102372380BDNF/NT-3 growth factors receptor. (415 aa)
MTTPMicrosomal triglyceride transfer protein large subunit. (893 aa)
ZPBP2Zona pellucida-binding protein 2. (353 aa)
CSNK1ECasein kinase I isoform X1; Belongs to the protein kinase superfamily. (417 aa)
METTL3N6-adenosine-methyltransferase catalytic subunit; Belongs to the MT-A70-like family. (571 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4 isoform X1. (352 aa)
DRD2D(2) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (301 aa)
EGR3Early growth response protein 3. (152 aa)
LOC102372737LOW QUALITY PROTEIN: period circadian protein homolog 2-like. (1315 aa)
CREB1Cyclic AMP-responsive element-binding protein 1. (327 aa)
MYBBP1AMyb-binding protein 1A. (1165 aa)
HDAC3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (405 aa)
PPARAPeroxisome proliferator-activated receptor alpha isoform X1. (468 aa)
NFIL3Nuclear factor interleukin-3-regulated protein. (447 aa)
THRAP3Thyroid hormone receptor-associated protein 3. (962 aa)
ATOH7Protein atonal homolog 7. (151 aa)
LOC102382695Neuronal PAS domain-containing protein 2. (698 aa)
CSNK1DCasein kinase I. (442 aa)
PROK2Prokineticin-2. (88 aa)
NR1D2Nuclear receptor subfamily 1 group D member 2 isoform X2. (588 aa)
LOC102372634DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (421 aa)
LOC106722193Nuclear factor interleukin-3-regulated protein-like. (394 aa)
ID2DNA-binding protein inhibitor ID-2. (271 aa)
LOC102384928Aryl hydrocarbon receptor-like. (1015 aa)
EP300Histone acetyltransferase p300 isoform X1. (2149 aa)
HTR75-hydroxytryptamine receptor 7. (418 aa)
HUWE1LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase HUWE1. (4398 aa)
NPAS2Neuronal PAS domain-containing protein 2 isoform X1. (825 aa)
PRMT5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (557 aa)
TIMELESSLOW QUALITY PROTEIN: protein timeless homolog. (1194 aa)
RORCNuclear receptor ROR-gamma isoform X1. (542 aa)
TOP1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (751 aa)
GPR157G-protein coupled receptor 157 isoform X1. (385 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X1. (680 aa)
CIARTCircadian-associated transcriptional repressor isoform X1. (467 aa)
LOC112548358Neuronal PAS domain-containing protein 2-like. (191 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (397 aa)
PER1Period circadian protein homolog 1 isoform X1. (1311 aa)
SIRT6NAD-dependent protein deacetylase sirtuin-6. (285 aa)
NAGLUalpha-N-acetylglucosaminidase. (711 aa)
AHRLOW QUALITY PROTEIN: aryl hydrocarbon receptor. (731 aa)
BTBD9BTB/POZ domain-containing protein 9 isoform X1. (671 aa)
GPR176G-protein coupled receptor 176 isoform X1. (529 aa)
CLOCKCircadian locomoter output cycles protein kaput. (883 aa)
LOC102372873Protein PML-like isoform X1. (652 aa)
LGR4Leucine-rich repeat-containing G-protein coupled receptor 4 isoform X1. (887 aa)
LOC102381221Aryl hydrocarbon receptor-like isoform X1. (1134 aa)
RORANuclear receptor ROR-alpha. (472 aa)
HOMER1Homer protein homolog 1 isoform X1. (367 aa)
CUNH3orf70UPF0524 protein C3orf70 homolog. (195 aa)
NGFRTumor necrosis factor receptor superfamily member 16. (427 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1 isoform X1. (637 aa)
NUDT12LOW QUALITY PROTEIN: peroxisomal NADH pyrophosphatase NUDT12. (470 aa)
LOC102382509Transmembrane protein FAM155A-like. (328 aa)
NMSneuromedin-S. (79 aa)
NOCTNocturnin isoform X1. (417 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (323 aa)
CARTPTCocaine- and amphetamine-regulated transcript protein. (69 aa)
AANATSerotonin N-acetyltransferase. (205 aa)
EGR2E3 SUMO-protein ligase EGR2. (357 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (266 aa)
MC3RMelanocortin receptor 3. (326 aa)
PAX4Paired box protein Pax-4. (434 aa)
MYCBP2E3 ubiquitin-protein ligase MYCBP2. (4641 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (326 aa)
LOC102381255RNA-binding protein 4B isoform X1. (364 aa)
BHLHE41Class E basic helix-loop-helix protein 41 isoform X1. (231 aa)
PER3LOW QUALITY PROTEIN: period circadian protein homolog 3. (218 aa)
NTRK1Tyrosine-protein kinase receptor. (816 aa)
SETXProbable helicase senataxin isoform X1. (2872 aa)
TNFRSF11ATumor necrosis factor receptor superfamily member 11A. (669 aa)
LOC102377832Nuclear receptor subfamily 1 group D member 1-like. (516 aa)
ATF5Cyclic AMP-dependent transcription factor ATF-5. (376 aa)
HNF1BHepatocyte nuclear factor 1-beta. (513 aa)
NDUFA9NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial. (378 aa)
KLF10Krueppel-like factor 10 isoform X1. (497 aa)
NAMPTNicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (504 aa)
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
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