65 items (Alligator sinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AMER3	APC membrane recruitment protein 3. (1013 aa)
	CTNNBIP1	Beta-catenin-interacting protein 1. (81 aa)
	BCL9	B-cell CLL/lymphoma 9 protein isoform X1. (1427 aa)
	ASH2L	set1/Ash2 histone methyltransferase complex subunit ASH2 isoform X2. (495 aa)
	CDH5	Cadherin-5 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (778 aa)
	AXIN2	Axin-2 isoform X1. (836 aa)
	SUFU	Suppressor of fused homolog. (452 aa)
	AMER2	APC membrane recruitment protein 2. (625 aa)
	PTPRJ	Receptor-type tyrosine-protein phosphatase eta isoform X1. (1350 aa)
	CTNNA2	Catenin alpha-2 isoform X3. (966 aa)
	LOC102378850	Na(+)/H(+) exchange regulatory cofactor NHE-RF1. (243 aa)
	PSEN1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (468 aa)
	AXIN1	Axin-1. (877 aa)
	GJA1	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (381 aa)
	CXADR	Coxsackievirus and adenovirus receptor isoform X1. (368 aa)
	CBY1	Protein chibby homolog 1. (126 aa)
	NUMB	Protein numb homolog isoform X1. (658 aa)
	CDH24	Cadherin-24. (629 aa)
	CTNNB1	Catenin beta-1. (784 aa)
	TBL1X	F-box-like/WD repeat-containing protein TBL1X isoform X1. (523 aa)
	SLC9A3R2	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (335 aa)
	LOC102375165	Mediator of RNA polymerase II transcription subunit 12-like protein. (1182 aa)
	PRKN	RBR-type E3 ubiquitin transferase. (504 aa)
	FOXO4	Forkhead box protein O4 isoform X1. (427 aa)
	FOXO1	Forkhead box protein O1. (473 aa)
	EP300	Histone acetyltransferase p300 isoform X1. (2149 aa)
	MED12L	Mediator of RNA polymerase II transcription subunit 12-like protein isoform X1. (1033 aa)
	AJAP1	Adherens junction-associated protein 1. (409 aa)
	BCL9L	LOW QUALITY PROTEIN: B-cell CLL/lymphoma 9-like protein. (1491 aa)
	KDM6B	LOW QUALITY PROTEIN: lysine-specific demethylase 6B. (1098 aa)
	LOC102381867	F-box/WD repeat-containing protein 1A. (517 aa)
	DACT2	Dapper homolog 2. (840 aa)
	RUVBL2	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (551 aa)
	APC2	LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2. (2427 aa)
	TCF7	Transcription factor 7 isoform X1. (482 aa)
	DLG5	Disks large homolog 5 isoform X1; Belongs to the MAGUK family. (1969 aa)
	AR	Androgen receptor isoform X2. (430 aa)
	GLI3	Transcriptional activator GLI3 isoform X1. (1584 aa)
	PTPRU	Receptor-type tyrosine-protein phosphatase U isoform X1. (1471 aa)
	LOC102382623	Uncharacterized protein LOC102382623 isoform X1. (195 aa)
	TCF7L2	Transcription factor 7-like 2 isoform X1. (584 aa)
	PIN1	Peptidyl-prolyl cis-trans isomerase. (159 aa)
	KANK1	KN motif and ankyrin repeat domain-containing protein 1 isoform X1. (1366 aa)
	KANK2	KN motif and ankyrin repeat domain-containing protein 2 isoform X1. (844 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (627 aa)
	CTNNA3	LOW QUALITY PROTEIN: catenin alpha-3. (901 aa)
	CTNNA1	LOW QUALITY PROTEIN: catenin alpha-1. (912 aa)
	CDH26	Cadherin-like protein 26 isoform X1. (824 aa)
	MED12	Mediator of RNA polymerase II transcription subunit 12. (2147 aa)
	KANK3	LOW QUALITY PROTEIN: KN motif and ankyrin repeat domain-containing protein 3. (1039 aa)
	DACT1	Dapper homolog 1 isoform X1. (730 aa)
	APC	Adenomatous polyposis coli protein isoform X1. (2849 aa)
	FOXO3	Forkhead box protein O3. (488 aa)
	AMER1	LOW QUALITY PROTEIN: APC membrane recruitment protein 1. (1145 aa)
	LOC112551352	Uncharacterized protein LOC112551352. (1464 aa)
	SMAD7	Mothers against decapentaplegic homolog. (284 aa)
	CALCOCO1	Calcium-binding and coiled-coil domain-containing protein 1. (689 aa)
	LZIC	Protein LZIC isoform X1. (317 aa)
	PTPRK	Receptor-type tyrosine-protein phosphatase kappa. (1490 aa)
	NUMBL	Numb-like protein. (429 aa)
	LEF1	Lymphoid enhancer-binding factor 1. (349 aa)
	TBL1XR1	F-box-like/WD repeat-containing protein TBL1XR1 isoform X1. (519 aa)
	VCL	Vinculin isoform X1. (1138 aa)
	TCF7L1	Transcription factor 7-like 1. (454 aa)
	SOX30	Transcription factor SOX-30. (455 aa)

Your Current Organism:

Alligator sinensis

NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMER1	APC	A0A3Q0H5C1	A0A3Q0GXG2	LOW QUALITY PROTEIN: APC membrane recruitment protein 1.	Adenomatous polyposis coli protein isoform X1.	0.866
AMER1	APC2	A0A3Q0H5C1	A0A3Q0FXN0	LOW QUALITY PROTEIN: APC membrane recruitment protein 1.	LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2.	0.866
AMER1	AXIN1	A0A3Q0H5C1	A0A1U7RXR0	LOW QUALITY PROTEIN: APC membrane recruitment protein 1.	Axin-1.	0.824
AMER1	AXIN2	A0A3Q0H5C1	A0A1U7RNB9	LOW QUALITY PROTEIN: APC membrane recruitment protein 1.	Axin-2 isoform X1.	0.824
AMER1	CTNNB1	A0A3Q0H5C1	A0A1U7S8W7	LOW QUALITY PROTEIN: APC membrane recruitment protein 1.	Catenin beta-1.	0.900
AMER1	LOC102381867	A0A3Q0H5C1	A0A3Q0FUN1	LOW QUALITY PROTEIN: APC membrane recruitment protein 1.	F-box/WD repeat-containing protein 1A.	0.576
AMER1	LOC102382623	A0A3Q0H5C1	A0A3Q0GF03	LOW QUALITY PROTEIN: APC membrane recruitment protein 1.	Uncharacterized protein LOC102382623 isoform X1.	0.576
AMER2	AMER3	A0A1U7RNU8	A0A3Q0GYP7	APC membrane recruitment protein 2.	APC membrane recruitment protein 3.	0.582
AMER3	AMER2	A0A3Q0GYP7	A0A1U7RNU8	APC membrane recruitment protein 3.	APC membrane recruitment protein 2.	0.582
APC	AMER1	A0A3Q0GXG2	A0A3Q0H5C1	Adenomatous polyposis coli protein isoform X1.	LOW QUALITY PROTEIN: APC membrane recruitment protein 1.	0.866
APC	APC2	A0A3Q0GXG2	A0A3Q0FXN0	Adenomatous polyposis coli protein isoform X1.	LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2.	0.900
APC	AXIN1	A0A3Q0GXG2	A0A1U7RXR0	Adenomatous polyposis coli protein isoform X1.	Axin-1.	0.986
APC	AXIN2	A0A3Q0GXG2	A0A1U7RNB9	Adenomatous polyposis coli protein isoform X1.	Axin-2 isoform X1.	0.994
APC	CTNNB1	A0A3Q0GXG2	A0A1U7S8W7	Adenomatous polyposis coli protein isoform X1.	Catenin beta-1.	0.995
APC	CTNNBIP1	A0A3Q0GXG2	A0A1U7R2G0	Adenomatous polyposis coli protein isoform X1.	Beta-catenin-interacting protein 1.	0.551
APC	LEF1	A0A3Q0GXG2	A0A3Q0HAG0	Adenomatous polyposis coli protein isoform X1.	Lymphoid enhancer-binding factor 1.	0.563
APC	LOC102381867	A0A3Q0GXG2	A0A3Q0FUN1	Adenomatous polyposis coli protein isoform X1.	F-box/WD repeat-containing protein 1A.	0.629
APC	LOC102382623	A0A3Q0GXG2	A0A3Q0GF03	Adenomatous polyposis coli protein isoform X1.	Uncharacterized protein LOC102382623 isoform X1.	0.629
APC	TBL1X	A0A3Q0GXG2	A0A1U7S9M1	Adenomatous polyposis coli protein isoform X1.	F-box-like/WD repeat-containing protein TBL1X isoform X1.	0.900
APC	TBL1XR1	A0A3Q0GXG2	A0A3Q0HCS9	Adenomatous polyposis coli protein isoform X1.	F-box-like/WD repeat-containing protein TBL1XR1 isoform X1.	0.900