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| | SCARB1 | Scavenger receptor class B member 1 isoform X1; Belongs to the CD36 family. (473 aa) |
| | MBTPS1 | Membrane-bound transcription factor site-1 protease isoform X1. (1060 aa) |
| | LOC102386823 | 25-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family. (513 aa) |
| | NPC2 | NPC intracellular cholesterol transporter 2 isoform X1. (150 aa) |
| | LBR | lamin-B receptor. (606 aa) |
| | INSIG2 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (233 aa) |
| | CAT | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (528 aa) |
| | SC5D | Lathosterol oxidase; Belongs to the sterol desaturase family. (297 aa) |
| | DHCR7 | 7-dehydrocholesterol reductase. (475 aa) |
| | LOC102381626 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (511 aa) |
| | LDLR | Low-density lipoprotein receptor isoform X1. (920 aa) |
| | LSS | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (724 aa) |
| | LDLRAP1 | Low density lipoprotein receptor adapter protein 1 isoform X1. (332 aa) |
| | LOC102370886 | Isopentenyl-diphosphate Delta-isomerase 1. (227 aa) |
| | LIMA1 | LIM domain and actin-binding protein 1 isoform X1. (763 aa) |
| | MSMO1 | Methylsterol monooxygenase 1; Belongs to the sterol desaturase family. (294 aa) |
| | MVD | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (409 aa) |
| | STAR | Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (287 aa) |
| | ANGPTL3 | Angiopoietin-related protein 3. (462 aa) |
| | LOC102388360 | 24-hydroxycholesterol 7-alpha-hydroxylase isoform X1; Belongs to the cytochrome P450 family. (468 aa) |
| | APP | Amyloid-beta A4 protein isoform X1. (716 aa) |
| | VLDLR | Very low-density lipoprotein receptor. (861 aa) |
| | LOC102385037 | Methylsterol monooxygenase 1-like; Belongs to the sterol desaturase family. (279 aa) |
| | CDCP2 | CUB domain-containing protein 2. (523 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (563 aa) |
| | APOB | Apolipoprotein B-100. (3654 aa) |
| | CH25H | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. (274 aa) |
| | HDLBP | Vigilin isoform X1. (1264 aa) |
| | LCAT | Phosphatidylcholine-sterol acyltransferase. (580 aa) |
| | APOA1 | Apolipoprotein A-I. (259 aa) |
| | LOC102373750 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (512 aa) |
| | HMGCS2 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (512 aa) |
| | EBP | 3-beta-hydroxysteroid-Delta(8), Delta(7)-isomerase. (227 aa) |
| | LOC102374171 | Glucosylceramidase. (555 aa) |
| | LOC102374014 | Erlin-1 isoform X3. (294 aa) |
| | HMGCR | 3-hydroxy-3-methylglutaryl coenzyme A reductase. (904 aa) |
| | LOC102386214 | Lanosterol 14-alpha demethylase; Belongs to the cytochrome P450 family. (404 aa) |
| | APOF | Apolipoprotein F. (439 aa) |
| | SMPD1 | Sphingomyelin phosphodiesterase. (250 aa) |
| | LOC102384651 | Apolipoprotein B-100-like. (991 aa) |
| | LOC102383457 | Protein CLN8-like. (288 aa) |
| | CFTR | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1512 aa) |
| | LIPC | Hepatic triacylglycerol lipase. (498 aa) |
| | DISP3 | Protein dispatched homolog 3. (1350 aa) |
| | APOA4 | Apolipoprotein A-IV isoform X1. (396 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (165 aa) |
| | LOC102380768 | Squalene synthase-like isoform X1. (332 aa) |
| | LOC102376314 | Cholesterol 24-hydroxylase; Belongs to the cytochrome P450 family. (500 aa) |
| | MBTPS2 | Membrane-bound transcription factor site-2 protease isoform X1. (494 aa) |
| | TM7SF2 | LOW QUALITY PROTEIN: delta(14)-sterol reductase. (422 aa) |
| | NSDHL | Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; Belongs to the 3-beta-HSD family. (345 aa) |
| | TMEM130 | Transmembrane protein 130. (438 aa) |
| | LOC102385901 | Squalene synthase-like isoform X1. (371 aa) |
| | LOC102368591 | Squalene synthase-like. (425 aa) |
| | HSD17B7 | 3-keto-steroid reductase. (303 aa) |
| | CLN6 | Ceroid-lipofuscinosis neuronal protein 6. (434 aa) |
| | SCAP | Sterol regulatory element-binding protein cleavage-activating protein isoform X1. (1342 aa) |
| | NPC1L1 | LOW QUALITY PROTEIN: NPC1-like intracellular cholesterol transporter 1. (1385 aa) |
| | PIP4P1 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (197 aa) |
| | LIPE | LOW QUALITY PROTEIN: hormone-sensitive lipase. (702 aa) |
| | GBA2 | Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (833 aa) |
| | NPC1 | NPC intracellular cholesterol transporter 1. (1277 aa) |
| | LOC102387409 | Apolipoprotein A-II-like. (103 aa) |
| | ARV1 | Protein ARV1. (228 aa) |
| | LOC102375758 | Cytochrome P450 11B, mitochondrial-like. (480 aa) |
| | LRP5 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1593 aa) |
| | INSIG1 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. (232 aa) |
| | MVK | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (326 aa) |
| | SREBF1 | Sterol regulatory element-binding protein 1 isoform X2. (1237 aa) |
| | LOC102383216 | Protein CLN8-like. (288 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (461 aa) |
| | DHCR24 | Delta(24)-sterol reductase. (482 aa) |
| | LOC102385282 | Methylsterol monooxygenase 1-like; Belongs to the sterol desaturase family. (179 aa) |
| | LRP8 | Low-density lipoprotein receptor-related protein 8. (1181 aa) |
| | PCSK9 | Proprotein convertase subtilisin/kexin type 9. (666 aa) |
| | HMGCS1 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (545 aa) |
| | SQLE | Squalene monooxygenase. (655 aa) |
| | SREBF2 | Sterol regulatory element-binding protein 2 isoform X1. (1096 aa) |
| | G6PD | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (515 aa) |
| | APOA5 | Apolipoprotein A-V isoform X1. (365 aa) |
| | LOC102370558 | Erlin-2 isoform X1. (356 aa) |
| | LOC102371146 | Cholesterol 7-desaturase-like. (356 aa) |
| | LEPR | Leptin receptor isoform X1. (1156 aa) |
| | LOC102374423 | Glucosylceramidase. (545 aa) |
| | RUSC1 | RUN and SH3 domain-containing protein 1. (1198 aa) |
| | FDPS | Farnesyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (282 aa) |
| | CETP | LOW QUALITY PROTEIN: cholesteryl ester transfer protein. (223 aa) |
| | CUBN | Cubilin isoform X1. (3632 aa) |
