STRINGSTRING
NR1H3 NR1H3 PPARG PPARG ITGB3 ITGB3 ABHD5 ABHD5 PNPLA2 PNPLA2 LOC102376394 LOC102376394 NFKBIA NFKBIA PPARA PPARA PPARD PPARD TTC39B TTC39B ITGAV ITGAV OSBPL8 OSBPL8 LOC102378694 LOC102378694 NR1H2 NR1H2 PTPN2 PTPN2 LOC102381473 LOC102381473 TTC39A TTC39A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NR1H3LOW QUALITY PROTEIN: oxysterols receptor LXR-alpha. (414 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (475 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (783 aa)
ABHD51-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform X1. (372 aa)
PNPLA2Patatin-like phospholipase domain-containing protein 2. (483 aa)
LOC102376394Oxysterol-binding protein-related protein 8-like. (135 aa)
NFKBIANF-kappa-B inhibitor alpha. (316 aa)
PPARAPeroxisome proliferator-activated receptor alpha isoform X1. (468 aa)
PPARDPeroxisome proliferator-activated receptor delta isoform X1. (442 aa)
TTC39BTetratricopeptide repeat protein 39B isoform X1. (606 aa)
ITGAVIntegrin alpha-V isoform X1; Belongs to the integrin alpha chain family. (1036 aa)
OSBPL8Oxysterol-binding protein; Belongs to the OSBP family. (655 aa)
LOC102378694Patatin-like phospholipase domain-containing protein 3 isoform X1. (506 aa)
NR1H2Oxysterols receptor LXR-beta isoform X1. (438 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (447 aa)
LOC102381473LOW QUALITY PROTEIN: tetratricopeptide repeat protein 39A-like. (605 aa)
TTC39ATetratricopeptide repeat protein 39A isoform X1. (581 aa)
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
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