STRINGSTRING
MAPK9 MAPK9 BRSK2 BRSK2 MAST3 MAST3 PIKFYVE PIKFYVE MTOR MTOR MAP3K12 MAP3K12 SYK SYK LOC102373748 LOC102373748 PKN2 PKN2 LOC102387373 LOC102387373 LOC112551763 LOC112551763 ULK2 ULK2 TTBK2 TTBK2 LOC102371847 LOC102371847 HIPK3 HIPK3 SMG1 SMG1 RPS6KA2 RPS6KA2 LOC102370674 LOC102370674 TTK TTK TNKS TNKS SMTNL1 SMTNL1 PRKAA2 PRKAA2 MAST2 MAST2 LOC112550697 LOC112550697 MYO3A MYO3A CSNK1G2 CSNK1G2 LOC102368134 LOC102368134 PKD1 PKD1 PRKCB PRKCB STK32A STK32A CSNK2A1 CSNK2A1 PLK1 PLK1 CLSPN CLSPN CAMKV CAMKV MAPKAPK2 MAPKAPK2 KIAA1549 KIAA1549 LOC102385821 LOC102385821 MAPK13 MAPK13 LOC102382732 LOC102382732 LOC102381777 LOC102381777 PRKCH PRKCH DYRK2 DYRK2 PRKCQ PRKCQ STK38 STK38 PRKCZ PRKCZ NLK NLK PDK3 PDK3 CHEK2 CHEK2 PRKCG PRKCG BRSK1 BRSK1 RPS6KB1 RPS6KB1 MKNK1 MKNK1 AURKA AURKA LATS2 LATS2 TLK2 TLK2 LOC102388439 LOC102388439 STK32B STK32B MAPKAPK5 MAPKAPK5 VRK2 VRK2 MAPK12 MAPK12 PRKCD PRKCD BAK1 BAK1 MORC3 MORC3 LOC102382968 LOC102382968 DCLK3 DCLK3 CSNK1E CSNK1E DYRK4 DYRK4 MAPKAPK3 MAPKAPK3 CDK1 CDK1 LOC102372380 LOC102372380 VRK1 VRK1 IKBKB IKBKB CDC7 CDC7 TGFBR2 TGFBR2 DYRK3 DYRK3 SGK2 SGK2 DYRK1A DYRK1A PRKAA1 PRKAA1 RPS6KA3 RPS6KA3 ROCK1 ROCK1 TLK1 TLK1 LOC102368712 LOC102368712 RICTOR RICTOR TSSK4 TSSK4 LOC102386632 LOC102386632 AKT2 AKT2 BCL2 BCL2 ILK ILK PRKX PRKX PBK PBK RPS6KB2 RPS6KB2 AKT1 AKT1 PAK2 PAK2 GSK3A GSK3A SGK1 SGK1 CSNK1D CSNK1D BAX BAX LOC102371879 LOC102371879 CSNK1A1 CSNK1A1 MAPK1 MAPK1 CHUK CHUK LOC102372634 LOC102372634 MYO3B MYO3B IKBKE IKBKE ATR ATR CSNK2A2 CSNK2A2 MAP3K13 MAP3K13 PDGFB PDGFB LRRK2 LRRK2 RIPK1 RIPK1 LATS1 LATS1 LOC102379044 LOC102379044 STK32C STK32C LOC102373194 LOC102373194 CAMK1 CAMK1 PRKCI PRKCI LOC102377785 LOC102377785 TBK1 TBK1 LOC102379795 LOC102379795 RPS6KA5 RPS6KA5 STK38L STK38L LOC102373602 LOC102373602 GSK3B GSK3B TOP1 TOP1 LOC102374947 LOC102374947 PDPK1 PDPK1 LOC102371867 LOC102371867 HIPK1 HIPK1 LOC102375250 LOC102375250 UHMK1 UHMK1 TTBK1 TTBK1 PINK1 PINK1 LOC102374620 LOC102374620 GAS6 GAS6 EIF2AK3 EIF2AK3 MAPK7 MAPK7 LOC102383851 LOC102383851 ULK1 ULK1 PRKCA PRKCA TGFBR1 TGFBR1 LOC102372537 LOC102372537 DGKQ DGKQ ULK3 ULK3 RPS6KA1 RPS6KA1 PRKDC PRKDC CSNK1G1 CSNK1G1 MAST4 MAST4 CSNK1G3 CSNK1G3 ROCK2 ROCK2 CAMK1D CAMK1D AKT3 AKT3 CAMK4 CAMK4 MAST1 MAST1 MASTL MASTL VRK3 VRK3 PRKCE PRKCE PKN3 PKN3 NEK7 NEK7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK9Mitogen-activated protein kinase. (424 aa)
BRSK2Serine/threonine-protein kinase BRSK2. (710 aa)
MAST3Microtubule-associated serine/threonine-protein kinase 3 isoform X1. (1560 aa)
PIKFYVE1-phosphatidylinositol 3-phosphate 5-kinase. (2126 aa)
MTORSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2551 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase. (798 aa)
SYKTyrosine-protein kinase SYK isoform X1. (658 aa)
LOC102373748Periaxin. (1151 aa)
PKN2Serine/threonine-protein kinase N2 isoform X1. (954 aa)
LOC102387373Serine-protein kinase ATM isoform X1; Belongs to the PI3/PI4-kinase family. (1934 aa)
LOC112551763Uncharacterized serine/threonine-protein kinase SgK494. (296 aa)
ULK2Serine/threonine-protein kinase ULK2. (1000 aa)
TTBK2Tau-tubulin kinase 2 isoform X1. (1346 aa)
LOC102371847Microtubule-associated serine/threonine-protein kinase 4-like. (184 aa)
HIPK3Homeodomain-interacting protein kinase 3 isoform X1. (1228 aa)
SMG1Serine/threonine-protein kinase SMG1 isoform X1; Belongs to the PI3/PI4-kinase family. (3532 aa)
RPS6KA2Ribosomal protein S6 kinase. (733 aa)
LOC102370674Dual specificity tyrosine-phosphorylation-regulated kinase 1B. (599 aa)
TTKDual specificity protein kinase TTK. (877 aa)
TNKSPoly [ADP-ribose] polymerase. (1148 aa)
SMTNL1Smoothelin-like protein 1 isoform X1. (479 aa)
PRKAA2Non-specific serine/threonine protein kinase. (461 aa)
MAST2Microtubule-associated serine/threonine-protein kinase 2 isoform X1. (1991 aa)
LOC112550697Microtubule-associated serine/threonine-protein kinase 2-like. (155 aa)
MYO3Amyosin-IIIa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1635 aa)
CSNK1G2Casein kinase I isoform X1; Belongs to the protein kinase superfamily. (451 aa)
LOC102368134Non-specific serine/threonine protein kinase. (715 aa)
PKD1Polycystin-1. (4304 aa)
PRKCBNon-specific serine/threonine protein kinase. (544 aa)
STK32ASerine/threonine-protein kinase 32A isoform X1; Belongs to the protein kinase superfamily. (396 aa)
CSNK2A1Casein kinase II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (391 aa)
PLK1Serine/threonine-protein kinase PLK1. (479 aa)
CLSPNClaspin. (1349 aa)
CAMKVcaM kinase-like vesicle-associated protein. (402 aa)
MAPKAPK2MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (375 aa)
KIAA1549UPF0606 protein KIAA1549 homolog. (1921 aa)
LOC102385821Tyrosine-protein kinase receptor. (363 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
LOC102382732Interleukin-20-like. (177 aa)
LOC102381777Uncharacterized protein F13E9.13, mitochondrial-like. (273 aa)
PRKCHProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (669 aa)
DYRK2Dual specificity tyrosine-phosphorylation-regulated kinase 2. (526 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (708 aa)
STK38Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (465 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (525 aa)
PDK3Protein-serine/threonine kinase. (360 aa)
CHEK2Serine/threonine-protein kinase Chk2. (441 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (689 aa)
BRSK1Serine/threonine-protein kinase BRSK1. (639 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (472 aa)
MKNK1LOW QUALITY PROTEIN: MAP kinase-interacting serine/threonine-protein kinase 1. (470 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (416 aa)
LATS2Non-specific serine/threonine protein kinase. (1127 aa)
TLK2Serine/threonine-protein kinase tousled-like 2. (750 aa)
LOC102388439Testis-specific serine/threonine-protein kinase 6; Belongs to the protein kinase superfamily. (277 aa)
STK32BSerine/threonine-protein kinase 32B. (376 aa)
MAPKAPK5MAP kinase-activated protein kinase 5 isoform X1. (473 aa)
VRK2Serine/threonine-protein kinase VRK2 isoform X1. (481 aa)
MAPK12Mitogen-activated protein kinase. (361 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (685 aa)
BAK1Bcl-2 homologous antagonist/killer isoform X1. (251 aa)
MORC3MORC family CW-type zinc finger protein 3. (579 aa)
LOC102382968Interleukin-20-like. (270 aa)
DCLK3Serine/threonine-protein kinase DCLK3. (795 aa)
CSNK1ECasein kinase I isoform X1; Belongs to the protein kinase superfamily. (417 aa)
DYRK4Dual specificity tyrosine-phosphorylation-regulated kinase 4. (612 aa)
MAPKAPK3MAP kinase-activated protein kinase 3 isoform X1; Belongs to the protein kinase superfamily. (387 aa)
CDK1LOW QUALITY PROTEIN: cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (311 aa)
LOC102372380BDNF/NT-3 growth factors receptor. (415 aa)
VRK1Serine/threonine-protein kinase VRK1 isoform X2; Belongs to the protein kinase superfamily. (415 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (757 aa)
CDC7Cell division cycle 7-related protein kinase. (563 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (531 aa)
DYRK3Dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform X1. (615 aa)
SGK2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (421 aa)
DYRK1ADual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1. (756 aa)
PRKAA1Non-specific serine/threonine protein kinase. (563 aa)
RPS6KA3Ribosomal protein S6 kinase. (727 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1377 aa)
TLK1Serine/threonine-protein kinase tousled-like 1. (679 aa)
LOC102368712Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
RICTORRapamycin-insensitive companion of mTOR isoform X1. (1674 aa)
TSSK4Testis-specific serine/threonine-protein kinase 4; Belongs to the protein kinase superfamily. (339 aa)
LOC102386632MAP kinase-interacting serine/threonine-protein kinase 2-like. (125 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (214 aa)
ILKIntegrin-linked protein kinase. (452 aa)
PRKXcAMP-dependent protein kinase catalytic subunit PRKX isoform X1. (307 aa)
PBKLymphokine-activated killer T-cell-originated protein kinase isoform X1. (325 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (475 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PAK2Non-specific serine/threonine protein kinase. (525 aa)
GSK3AGlycogen synthase kinase-3 alpha. (298 aa)
SGK1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (431 aa)
CSNK1DCasein kinase I. (442 aa)
BAXApoptosis regulator BAX isoform X1. (253 aa)
LOC102371879TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (565 aa)
CSNK1A1Casein kinase I isoform X1; Belongs to the protein kinase superfamily. (365 aa)
MAPK1Mitogen-activated protein kinase. (422 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha. (735 aa)
LOC102372634DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (421 aa)
MYO3Bmyosin-IIIb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1140 aa)
IKBKEInhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1. (752 aa)
ATRSerine/threonine-protein kinase ATR isoform X1; Belongs to the PI3/PI4-kinase family. (2655 aa)
CSNK2A2Casein kinase II subunit alpha' isoform X1; Belongs to the protein kinase superfamily. (323 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase. (966 aa)
PDGFBPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (276 aa)
LRRK2Leucine-rich repeat serine/threonine-protein kinase 2 isoform X1. (2410 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1 isoform X1. (711 aa)
LATS1Serine/threonine-protein kinase LATS1 isoform X1. (1138 aa)
LOC102379044MAP kinase-interacting serine/threonine-protein kinase 2 isoform X1. (339 aa)
STK32CSerine/threonine-protein kinase 32C isoform X4; Belongs to the protein kinase superfamily. (401 aa)
LOC102373194Casein kinase II subunit alpha-like isoform X1; Belongs to the protein kinase superfamily. (392 aa)
CAMK1Calcium/calmodulin-dependent protein kinase type 1. (462 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (560 aa)
LOC102377785Calcium/calmodulin-dependent protein kinase type IV-like; Belongs to the protein kinase superfamily. (399 aa)
TBK1Serine/threonine-protein kinase TBK1 isoform X1. (741 aa)
LOC102379795Serine/threonine-protein kinase DCLK1 isoform X1. (749 aa)
RPS6KA5Ribosomal protein S6 kinase. (808 aa)
STK38LNon-specific serine/threonine protein kinase. (510 aa)
LOC102373602Serine/threonine-protein kinase N1. (1062 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (409 aa)
TOP1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (751 aa)
LOC102374947Serine-protein kinase ATM-like. (111 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X2. (701 aa)
LOC102371867Non-specific serine/threonine protein kinase. (1284 aa)
HIPK1LOW QUALITY PROTEIN: homeodomain-interacting protein kinase 1. (1216 aa)
LOC102375250Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (564 aa)
UHMK1Serine/threonine-protein kinase Kist isoform X1. (366 aa)
TTBK1Tau-tubulin kinase 1. (1330 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial. (364 aa)
LOC102374620myosin-IIIb-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1042 aa)
GAS6Growth arrest-specific protein 6. (667 aa)
EIF2AK3Eukaryotic translation initiation factor 2-alpha kinase 3 isoform X2. (1001 aa)
MAPK7Mitogen-activated protein kinase. (885 aa)
LOC102383851Aurora kinase B-like; Belongs to the protein kinase superfamily. (315 aa)
ULK1LOW QUALITY PROTEIN: serine/threonine-protein kinase ULK1. (1031 aa)
PRKCANon-specific serine/threonine protein kinase. (552 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (440 aa)
LOC102372537Polycystin-1-like. (4207 aa)
DGKQDiacylglycerol kinase. (845 aa)
ULK3Serine/threonine-protein kinase ULK3 isoform X1. (446 aa)
RPS6KA1Ribosomal protein S6 kinase. (757 aa)
PRKDCDNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family. (4104 aa)
CSNK1G1Casein kinase I isoform X1; Belongs to the protein kinase superfamily. (467 aa)
MAST4Microtubule-associated serine/threonine-protein kinase 4 isoform X1. (2437 aa)
CSNK1G3Casein kinase I isoform X1; Belongs to the protein kinase superfamily. (456 aa)
ROCK2Rho-associated protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1455 aa)
CAMK1DCalcium/calmodulin-dependent protein kinase type 1D isoform X1. (386 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
CAMK4Calcium/calmodulin-dependent protein kinase type IV. (332 aa)
MAST1Microtubule-associated serine/threonine-protein kinase 1. (1627 aa)
MASTLSerine/threonine-protein kinase greatwall isoform X1. (896 aa)
VRK3Inactive serine/threonine-protein kinase VRK3. (443 aa)
PRKCEProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (742 aa)
PKN3Serine/threonine-protein kinase N3 isoform X2. (967 aa)
NEK7Serine/threonine-protein kinase Nek7 isoform X2; Belongs to the protein kinase superfamily. (361 aa)
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
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