STRINGSTRING
LOC102375321 LOC102375321 LOC102376405 LOC102376405 TPD52 TPD52 LFNG LFNG CLCF1 CLCF1 LOC102378889 LOC102378889 NTRK1 NTRK1 LOC102372412 LOC102372412 LOC102387373 LOC102387373 TOX TOX CMTM7 CMTM7 DCAF1 DCAF1 GATA3 GATA3 LEF1 LEF1 IL18R1 IL18R1 THEMIS THEMIS SYK SYK TNFSF8 TNFSF8 LEPR LEPR MTOR MTOR NKX2-6 NKX2-6 IL6 IL6 STAT3 STAT3 LOC102370479 LOC102370479 IKZF1 IKZF1 LOC102380420 LOC102380420 MFNG MFNG LOC102382314 LOC102382314 MSH2 MSH2 DLL4 DLL4 PTPN2 PTPN2 TUSC2 TUSC2 BCL11B BCL11B HLX HLX HECTD1 HECTD1 LOC112549790 LOC112549790 DOCK10 DOCK10 GLI3 GLI3 LOC102374052 LOC102374052 RORA RORA SP3 SP3 CDH17 CDH17 CBFB CBFB GPR89B GPR89B TSHR TSHR JMJD6 JMJD6 TCF7 TCF7 FNIP1 FNIP1 LOC102375912 LOC102375912 ARMC5 ARMC5 TP53 TP53 LOC102376089 LOC102376089 RIPK3 RIPK3 STAT6 STAT6 AXL AXL LOC102384900 LOC102384900 LOC102374947 LOC102374947 LOC102379235 LOC102379235 RORC RORC LOC102387054 LOC102387054 PRR7 PRR7 CD4 CD4 CD3E CD3E SOX13 SOX13 LOC102385553 LOC102385553 RC3H2 RC3H2 TNFSF13B TNFSF13B IL15 IL15 RHOH RHOH TESPA1 TESPA1 ITFG2 ITFG2 CEBPG CEBPG LEP LEP LOC106722594 LOC106722594 FZD5 FZD5 TMEM98 TMEM98 ITM2A ITM2A LOC102374298 LOC102374298 EP300 EP300 FLT3 FLT3 PTPRC PTPRC KIT KIT CCR7 CCR7 RIPK2 RIPK2 RC3H1 RC3H1 TRAF3IP2 TRAF3IP2 BAX BAX CD79A CD79A RAG1 RAG1 LIG4 LIG4 CD3D CD3D LOC102375342 LOC102375342 TGFB1 TGFB1 SRF SRF CARD11 CARD11 CCR9 CCR9 ABL2 ABL2 BLNK BLNK FOXN1 FOXN1 RABL3 RABL3 BCL2 BCL2 WNT1 WNT1 NFAM1 NFAM1 CD8A CD8A CD40LG CD40LG TSC1 TSC1 FADD FADD DNAJB9 DNAJB9 ZBTB7A ZBTB7A CD79B CD79B ZBTB1 ZBTB1 MALT1 MALT1 BATF BATF BRAF BRAF RSAD2 RSAD2 ATG5 ATG5 IRF1 IRF1 CD74 CD74 RAG2 RAG2 PAX1 PAX1 IKZF3 IKZF3 LOC102385202 LOC102385202 CD83 CD83 DLL1 DLL1 GPR18 GPR18 STK11 STK11 ANXA1 ANXA1 LRRC8A LRRC8A LOC102370889 LOC102370889 LGALS1 LGALS1 LOC102376462 LOC102376462 IL7R IL7R POU2AF1 POU2AF1 EOMES EOMES GPR183 GPR183 FBXO7 FBXO7 TBX21 TBX21 NCAPH2 NCAPH2 MERTK MERTK BAK1 BAK1 ABL1 ABL1 LOC102379481 LOC102379481 SASH3 SASH3 CTNNB1 CTNNB1 JAG2 JAG2 PTGER4 PTGER4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102375321Interferon epsilon-like. (196 aa)
LOC102376405Interferon alpha-2-like. (224 aa)
TPD52Tumor protein D52 isoform X1. (230 aa)
LFNGbeta-1,3-N-acetylglucosaminyltransferase lunatic fringe. (258 aa)
CLCF1Cardiotrophin-like cytokine factor 1 isoform X1. (255 aa)
LOC102378889Homeobox protein PKNOX1 isoform X1. (332 aa)
NTRK1Tyrosine-protein kinase receptor. (816 aa)
LOC102372412GON-4-like protein isoform X1. (1999 aa)
LOC102387373Serine-protein kinase ATM isoform X1; Belongs to the PI3/PI4-kinase family. (1934 aa)
TOXThymocyte selection-associated high mobility group box protein TOX isoform X1. (544 aa)
CMTM7CKLF-like MARVEL transmembrane domain-containing protein 7. (172 aa)
DCAF1DDB1- and CUL4-associated factor 1 isoform X1. (1509 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3. (385 aa)
LEF1Lymphoid enhancer-binding factor 1. (349 aa)
IL18R1Interleukin-18 receptor 1. (413 aa)
THEMISProtein THEMIS. (686 aa)
SYKTyrosine-protein kinase SYK isoform X1. (658 aa)
TNFSF8Tumor necrosis factor ligand superfamily member 8; Belongs to the tumor necrosis factor family. (233 aa)
LEPRLeptin receptor isoform X1. (1156 aa)
MTORSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2551 aa)
NKX2-6Homeobox protein Nkx-2.6. (369 aa)
IL6Interleukin-6. (152 aa)
STAT3Signal transducer and activator of transcription. (771 aa)
LOC102370479Signal transducer and activator of transcription 5B-like. (247 aa)
IKZF1DNA-binding protein Ikaros isoform X1. (528 aa)
LOC102380420Signal transducer and activator of transcription. (822 aa)
MFNGBeta-1,3-N-acetylglucosaminyltransferase. (351 aa)
LOC102382314Mucosa-associated lymphoid tissue lymphoma translocation protein 1-like. (785 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (891 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (615 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (447 aa)
TUSC2Tumor suppressor candidate 2. (70 aa)
BCL11BLOW QUALITY PROTEIN: B-cell lymphoma/leukemia 11B. (886 aa)
HLXH2.0-like homeobox protein. (255 aa)
HECTD1E3 ubiquitin-protein ligase HECTD1 isoform X1. (2576 aa)
LOC112549790Uncharacterized protein LOC112549790. (359 aa)
DOCK10Dedicator of cytokinesis protein 10 isoform X1; Belongs to the DOCK family. (2204 aa)
GLI3Transcriptional activator GLI3 isoform X1. (1584 aa)
LOC102374052Mucosa-associated lymphoid tissue lymphoma translocation protein 1-like isoform X1. (647 aa)
RORANuclear receptor ROR-alpha. (472 aa)
SP3Transcription factor Sp3 isoform X1. (702 aa)
CDH17Cadherin-17 isoform X1. (843 aa)
CBFBCore-binding factor subunit beta isoform X1. (211 aa)
GPR89BGolgi pH regulator B isoform X1. (484 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (717 aa)
JMJD6Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6. (373 aa)
TCF7Transcription factor 7 isoform X1. (482 aa)
FNIP1Folliculin-interacting protein 1 isoform X2. (1150 aa)
LOC102375912Galectin. (201 aa)
ARMC5Armadillo repeat-containing protein 5. (1001 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (397 aa)
LOC102376089semaphorin-4A isoform X1; Belongs to the semaphorin family. (882 aa)
RIPK3Receptor-interacting serine/threonine-protein kinase 3 isoform X1. (509 aa)
STAT6Signal transducer and activator of transcription. (976 aa)
AXLTyrosine-protein kinase receptor UFO. (558 aa)
LOC102384900Interleukin-4 receptor subunit alpha. (1180 aa)
LOC102374947Serine-protein kinase ATM-like. (111 aa)
LOC102379235Tyrosine-protein kinase. (612 aa)
RORCNuclear receptor ROR-gamma isoform X1. (542 aa)
LOC102387054Signaling lymphocytic activation molecule. (331 aa)
PRR7Proline-rich protein 7. (114 aa)
CD4T-cell surface glycoprotein CD4. (491 aa)
CD3ET-cell surface glycoprotein CD3 epsilon chain. (187 aa)
SOX13Transcription factor SOX-13 isoform X1. (621 aa)
LOC102385553Homeobox protein PKNOX1-like. (117 aa)
RC3H2Roquin-2 isoform X1. (1191 aa)
TNFSF13BTumor necrosis factor ligand superfamily member 13B isoform X1; Belongs to the tumor necrosis factor family. (330 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (219 aa)
RHOHRho-related GTP-binding protein RhoH. (191 aa)
TESPA1Protein TESPA1. (674 aa)
ITFG2KICSTOR complex protein ITFG2 isoform X1. (467 aa)
CEBPGCCAAT/enhancer-binding protein gamma. (150 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (165 aa)
LOC106722594Frizzled-8-like; Belongs to the G-protein coupled receptor Fz/Smo family. (155 aa)
FZD5LOW QUALITY PROTEIN: frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (510 aa)
TMEM98Transmembrane protein 98. (226 aa)
ITM2AIntegral membrane protein 2A. (251 aa)
LOC102374298Receptor-interacting serine/threonine-protein kinase 2-like. (565 aa)
EP300Histone acetyltransferase p300 isoform X1. (2149 aa)
FLT3Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1014 aa)
PTPRCReceptor-type tyrosine-protein phosphatase C isoform X1. (1251 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (970 aa)
CCR7C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family. (315 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2. (510 aa)
RC3H1Roquin-1 isoform X1. (1138 aa)
TRAF3IP2Adapter protein CIKS isoform X1. (557 aa)
BAXApoptosis regulator BAX isoform X1. (253 aa)
CD79AB-cell antigen receptor complex-associated protein alpha chain. (354 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1026 aa)
LIG4DNA ligase. (914 aa)
CD3DT-cell surface glycoprotein CD3 delta chain. (138 aa)
LOC102375342Galectin. (138 aa)
TGFB1Transforming growth factor beta-1. (235 aa)
SRFSerum response factor isoform X1. (412 aa)
CARD11Caspase recruitment domain-containing protein 11 isoform X1. (1207 aa)
CCR9LOW QUALITY PROTEIN: C-C chemokine receptor type 9; Belongs to the G-protein coupled receptor 1 family. (358 aa)
ABL2Tyrosine-protein kinase. (1137 aa)
BLNKB-cell linker protein isoform X1. (603 aa)
FOXN1Forkhead box protein N1 isoform X1. (646 aa)
RABL3Rab-like protein 3. (236 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (214 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (341 aa)
NFAM1NFAT activation molecule 1. (280 aa)
CD8AT-cell surface glycoprotein CD8 alpha chain. (223 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (260 aa)
TSC1LOW QUALITY PROTEIN: hamartin. (1162 aa)
FADDFAS-associated death domain protein. (191 aa)
DNAJB9dnaJ homolog subfamily B member 9. (216 aa)
ZBTB7AZinc finger and BTB domain-containing protein 7A isoform X1. (555 aa)
CD79BB-cell antigen receptor complex-associated protein beta chain isoform X1. (226 aa)
ZBTB1Zinc finger and BTB domain-containing protein 1 isoform X1. (710 aa)
MALT1Mucosa-associated lymphoid tissue lymphoma translocation protein 1. (770 aa)
BATFBasic leucine zipper transcriptional factor ATF-like. (128 aa)
BRAFSerine/threonine-protein kinase B-raf. (735 aa)
RSAD2LOW QUALITY PROTEIN: radical S-adenosyl methionine domain-containing protein 2. (336 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
IRF1Interferon regulatory factor. (318 aa)
CD74HLA class II histocompatibility antigen gamma chain. (285 aa)
RAG2V(D)J recombination-activating protein 2. (534 aa)
PAX1Paired box protein Pax-1. (367 aa)
IKZF3Zinc finger protein Aiolos isoform X1. (512 aa)
LOC102385202B-lymphocyte antigen CD20-like. (229 aa)
CD83CD83 antigen. (217 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (734 aa)
GPR18N-arachidonyl glycine receptor; Belongs to the G-protein coupled receptor 1 family. (328 aa)
STK11Serine/threonine-protein kinase STK11 isoform X1; Belongs to the protein kinase superfamily. (440 aa)
ANXA1Annexin. (342 aa)
LRRC8AVolume-regulated anion channel subunit LRRC8A. (810 aa)
LOC102370889Interferon epsilon-like. (186 aa)
LGALS1Galectin. (134 aa)
LOC102376462Interferon alpha-7. (223 aa)
IL7RInterleukin-7 receptor subunit alpha. (464 aa)
POU2AF1POU domain class 2-associating factor 1. (256 aa)
EOMESEomesodermin homolog isoform X1. (414 aa)
GPR183G-protein coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (377 aa)
FBXO7F-box only protein 7 isoform X1. (531 aa)
TBX21T-box transcription factor TBX21. (396 aa)
NCAPH2LOW QUALITY PROTEIN: condensin-2 complex subunit H2. (580 aa)
MERTKTyrosine-protein kinase Mer isoform X1. (940 aa)
BAK1Bcl-2 homologous antagonist/killer isoform X1. (251 aa)
ABL1Tyrosine-protein kinase. (1139 aa)
LOC102379481Galectin. (134 aa)
SASH3SAM and SH3 domain-containing protein 3 isoform X1. (382 aa)
CTNNB1Catenin beta-1. (784 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1228 aa)
PTGER4Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (486 aa)
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
Server load: low (22%) [HD]