40 items (Alligator sinensis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	STARD4	stAR-related lipid transfer protein 4 isoform X1. (207 aa)
	VPS4A	Vacuolar protein sorting-associated protein 4A; Belongs to the AAA ATPase family. (342 aa)
	LCAT	Phosphatidylcholine-sterol acyltransferase. (580 aa)
	VPS4B	Vacuolar protein sorting-associated protein 4B; Belongs to the AAA ATPase family. (441 aa)
	STARD5	stAR-related lipid transfer protein 5. (182 aa)
	LOC102384651	Apolipoprotein B-100-like. (991 aa)
	APOE	Apolipoprotein E isoform X1. (252 aa)
	CFTR	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1512 aa)
	LIPC	Hepatic triacylglycerol lipase. (498 aa)
	STARD3NL	STARD3 N-terminal-like protein. (234 aa)
	APOA4	Apolipoprotein A-IV isoform X1. (396 aa)
	ABCG8	ATP-binding cassette sub-family G member 8. (677 aa)
	APOM	Apolipoprotein M. (184 aa)
	NPC1L1	LOW QUALITY PROTEIN: NPC1-like intracellular cholesterol transporter 1. (1385 aa)
	SPG11	Spatacsin isoform X1. (2418 aa)
	LOC102382357	Steroidogenic acute regulatory protein, mitochondrial-like. (321 aa)
	NPC1	NPC intracellular cholesterol transporter 1. (1277 aa)
	LOC102387409	Apolipoprotein A-II-like. (103 aa)
	ARV1	Protein ARV1. (228 aa)
	TPCN2	Two pore calcium channel protein 2. (776 aa)
	STARD3	stAR-related lipid transfer protein 3. (444 aa)
	SERAC1	Protein SERAC1 isoform X1. (749 aa)
	SYT7	Synaptotagmin-7. (679 aa)
	ABCG4	ATP-binding cassette sub-family G member 4 isoform X1. (596 aa)
	SCP2	Non-specific lipid-transfer protein isoform X1; Belongs to the thiolase-like superfamily. Thiolase family. (507 aa)
	RELCH	lisH domain and HEAT repeat-containing protein KIAA1468 homolog isoform X1. (1060 aa)
	APOA5	Apolipoprotein A-V isoform X1. (365 aa)
	CETP	LOW QUALITY PROTEIN: cholesteryl ester transfer protein. (223 aa)
	ABCG1	ATP-binding cassette sub-family G member 1. (677 aa)
	OSBPL2	Oxysterol-binding protein; Belongs to the OSBP family. (481 aa)
	LRP6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1604 aa)
	LDLRAP1	Low density lipoprotein receptor adapter protein 1 isoform X1. (332 aa)
	CEL	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (559 aa)
	LIMA1	LIM domain and actin-binding protein 1 isoform X1. (763 aa)
	STAR	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (287 aa)
	ABCG5	ATP-binding cassette sub-family G member 5. (638 aa)
	SCARB1	Scavenger receptor class B member 1 isoform X1; Belongs to the CD36 family. (473 aa)
	NPC2	NPC intracellular cholesterol transporter 2 isoform X1. (150 aa)
	APOB	Apolipoprotein B-100. (3654 aa)
	PODN	Podocan. (600 aa)

Your Current Organism:

Alligator sinensis

NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCG1	ABCG5	A0A3Q0HLL6	A0A1U7S1S3	ATP-binding cassette sub-family G member 1.	ATP-binding cassette sub-family G member 5.	0.783
ABCG4	ABCG5	A0A3Q0GVI2	A0A1U7S1S3	ATP-binding cassette sub-family G member 4 isoform X1.	ATP-binding cassette sub-family G member 5.	0.783
ABCG5	ABCG1	A0A1U7S1S3	A0A3Q0HLL6	ATP-binding cassette sub-family G member 5.	ATP-binding cassette sub-family G member 1.	0.783
ABCG5	ABCG4	A0A1U7S1S3	A0A3Q0GVI2	ATP-binding cassette sub-family G member 5.	ATP-binding cassette sub-family G member 4 isoform X1.	0.783
ABCG5	ABCG8	A0A1U7S1S3	A0A1U8DCY8	ATP-binding cassette sub-family G member 5.	ATP-binding cassette sub-family G member 8.	0.999
ABCG5	APOA4	A0A1U7S1S3	A0A1U8DBC9	ATP-binding cassette sub-family G member 5.	Apolipoprotein A-IV isoform X1.	0.404
ABCG5	NPC1	A0A1U7S1S3	A0A3Q0FVZ6	ATP-binding cassette sub-family G member 5.	NPC intracellular cholesterol transporter 1.	0.408
ABCG5	NPC1L1	A0A1U7S1S3	A0A3Q0FP67	ATP-binding cassette sub-family G member 5.	LOW QUALITY PROTEIN: NPC1-like intracellular cholesterol transporter 1.	0.408
ABCG8	ABCG5	A0A1U8DCY8	A0A1U7S1S3	ATP-binding cassette sub-family G member 8.	ATP-binding cassette sub-family G member 5.	0.999
ABCG8	APOB	A0A1U8DCY8	A0A1U7SB35	ATP-binding cassette sub-family G member 8.	Apolipoprotein B-100.	0.603
APOA4	ABCG5	A0A1U8DBC9	A0A1U7S1S3	Apolipoprotein A-IV isoform X1.	ATP-binding cassette sub-family G member 5.	0.404
APOA4	APOB	A0A1U8DBC9	A0A1U7SB35	Apolipoprotein A-IV isoform X1.	Apolipoprotein B-100.	0.581
APOA4	APOE	A0A1U8DBC9	A0A1U7SXQ0	Apolipoprotein A-IV isoform X1.	Apolipoprotein E isoform X1.	0.828
APOA4	APOM	A0A1U8DBC9	A0A1U8DM82	Apolipoprotein A-IV isoform X1.	Apolipoprotein M.	0.438
APOA4	LOC102384651	A0A1U8DBC9	A0A1U7SVD5	Apolipoprotein A-IV isoform X1.	Apolipoprotein B-100-like.	0.581
APOA4	LOC102387409	A0A1U8DBC9	A0A3Q0FWD5	Apolipoprotein A-IV isoform X1.	Apolipoprotein A-II-like.	0.833
APOA4	STARD3	A0A1U8DBC9	A0A3Q0GGB3	Apolipoprotein A-IV isoform X1.	stAR-related lipid transfer protein 3.	0.453
APOA5	APOB	A0A3Q0H6S2	A0A1U7SB35	Apolipoprotein A-V isoform X1.	Apolipoprotein B-100.	0.579
APOA5	APOE	A0A3Q0H6S2	A0A1U7SXQ0	Apolipoprotein A-V isoform X1.	Apolipoprotein E isoform X1.	0.423
APOA5	LIPC	A0A3Q0H6S2	A0A1U8D805	Apolipoprotein A-V isoform X1.	Hepatic triacylglycerol lipase.	0.535