25 items (Alligator sinensis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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Predicted Interactions

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Your Input:
	MED1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1565 aa)
	ESR2	Estrogen receptor beta isoform X1. (548 aa)
	PADI2	LOW QUALITY PROTEIN: protein-arginine deiminase type-2. (387 aa)
	DDX5	Probable ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family. (611 aa)
	TRIP4	Activating signal cointegrator 1. (588 aa)
	AR	Androgen receptor isoform X2. (430 aa)
	PPARGC1B	Peroxisome proliferator-activated receptor gamma coactivator 1-beta isoform X1. (1022 aa)
	NR3C1	Glucocorticoid receptor isoform X1. (807 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (627 aa)
	RWDD1	RWD domain-containing protein 1. (144 aa)
	CALCOCO1	Calcium-binding and coiled-coil domain-containing protein 1. (689 aa)
	PGR	Progesterone receptor. (338 aa)
	TMF1	TATA element modulatory factor. (1070 aa)
	RBFOX2	RNA binding protein fox-1 homolog; RNA-binding protein that regulates alternative splicing events. (391 aa)
	UBR5	E3 ubiquitin-protein ligase UBR5. (2815 aa)
	LOC102381382	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (652 aa)
	DDX17	Probable ATP-dependent RNA helicase DDX17 isoform X1; Belongs to the DEAD box helicase family. (655 aa)
	GPER1	G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (358 aa)
	LOC102374514	Protein-arginine deiminase type-2-like. (278 aa)
	NKX3-1	Homeobox protein Nkx-3.1 isoform X1. (232 aa)
	DAXX	Death domain-associated protein 6. (767 aa)
	TRERF1	Transcriptional-regulating factor 1 isoform X1. (1178 aa)
	UBE3A	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (879 aa)
	LOC102386823	25-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family. (513 aa)
	PHB	Prohibitin. (273 aa)

Your Current Organism:

Alligator sinensis

NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AR	DAXX	A0A3Q0G8Z2	A0A1U7SAW3	Androgen receptor isoform X2.	Death domain-associated protein 6.	0.477
AR	ESR1	A0A3Q0G8Z2	A0A3Q0GNM7	Androgen receptor isoform X2.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.701
AR	ESR2	A0A3Q0G8Z2	A0A1U8D748	Androgen receptor isoform X2.	Estrogen receptor beta isoform X1.	0.406
AR	LOC102381382	A0A3Q0G8Z2	A0A1U8D0V4	Androgen receptor isoform X2.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.517
AR	MED1	A0A3Q0G8Z2	A0A1U8D3S0	Androgen receptor isoform X2.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.517
AR	NKX3-1	A0A3Q0G8Z2	A0A1U7SB75	Androgen receptor isoform X2.	Homeobox protein Nkx-3.1 isoform X1.	0.592
AR	NR3C1	A0A3Q0G8Z2	A0A3Q0GJE3	Androgen receptor isoform X2.	Glucocorticoid receptor isoform X1.	0.645
AR	PGR	A0A3Q0G8Z2	A0A3Q0H404	Androgen receptor isoform X2.	Progesterone receptor.	0.656
CALCOCO1	ESR1	A0A3Q0H8Z5	A0A3Q0GNM7	Calcium-binding and coiled-coil domain-containing protein 1.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.552
DAXX	AR	A0A1U7SAW3	A0A3Q0G8Z2	Death domain-associated protein 6.	Androgen receptor isoform X2.	0.477
DAXX	NR3C1	A0A1U7SAW3	A0A3Q0GJE3	Death domain-associated protein 6.	Glucocorticoid receptor isoform X1.	0.529
DDX17	DDX5	A0A1U7SG48	A0A3Q0G0U6	Probable ATP-dependent RNA helicase DDX17 isoform X1; Belongs to the DEAD box helicase family.	Probable ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family.	0.866
DDX17	ESR1	A0A1U7SG48	A0A3Q0GNM7	Probable ATP-dependent RNA helicase DDX17 isoform X1; Belongs to the DEAD box helicase family.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.841
DDX17	ESR2	A0A1U7SG48	A0A1U8D748	Probable ATP-dependent RNA helicase DDX17 isoform X1; Belongs to the DEAD box helicase family.	Estrogen receptor beta isoform X1.	0.601
DDX5	DDX17	A0A3Q0G0U6	A0A1U7SG48	Probable ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family.	Probable ATP-dependent RNA helicase DDX17 isoform X1; Belongs to the DEAD box helicase family.	0.866
DDX5	ESR1	A0A3Q0G0U6	A0A3Q0GNM7	Probable ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.848
DDX5	ESR2	A0A3Q0G0U6	A0A1U8D748	Probable ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family.	Estrogen receptor beta isoform X1.	0.601
ESR1	AR	A0A3Q0GNM7	A0A3Q0G8Z2	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Androgen receptor isoform X2.	0.701
ESR1	CALCOCO1	A0A3Q0GNM7	A0A3Q0H8Z5	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Calcium-binding and coiled-coil domain-containing protein 1.	0.552
ESR1	DDX17	A0A3Q0GNM7	A0A1U7SG48	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Probable ATP-dependent RNA helicase DDX17 isoform X1; Belongs to the DEAD box helicase family.	0.841