STRINGSTRING
MED1 MED1 LOC102381382 LOC102381382 PAGR1 PAGR1 ZNF366 ZNF366 UFL1 UFL1 CNOT1 CNOT1 LOC102374986 LOC102374986 DNAAF4 DNAAF4 UFSP2 UFSP2 LOC102386823 LOC102386823 KANK2 KANK2 VPS18 VPS18 CARM1 CARM1 TP63 TP63 BRCA1 BRCA1 DDRGK1 DDRGK1 AR AR CNOT9 CNOT9 VPS11 VPS11 CNOT2 CNOT2 LATS1 LATS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1565 aa)
LOC102381382Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (652 aa)
PAGR1PAXIP1-associated glutamate-rich protein 1 isoform X1. (214 aa)
ZNF366Zinc finger protein 366. (730 aa)
UFL1E3 UFM1-protein ligase 1. (755 aa)
CNOT1LOW QUALITY PROTEIN: CCR4-NOT transcription complex subunit 1. (2374 aa)
LOC102374986Histone-arginine methyltransferase CARM1-like isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (532 aa)
DNAAF4Dynein assembly factor 4, axonemal isoform X1. (416 aa)
UFSP2Ufm1-specific protease 2 isoform X1. (482 aa)
LOC10238682325-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family. (513 aa)
KANK2KN motif and ankyrin repeat domain-containing protein 2 isoform X1. (844 aa)
VPS18Vacuolar protein sorting-associated protein 18 homolog. (988 aa)
CARM1Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (548 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
BRCA1LOW QUALITY PROTEIN: breast cancer type 1 susceptibility protein. (1877 aa)
DDRGK1DDRGK domain-containing protein 1. (242 aa)
ARAndrogen receptor isoform X2. (430 aa)
CNOT9CCR4-NOT transcription complex subunit 9. (298 aa)
VPS11Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (877 aa)
CNOT2CCR4-NOT transcription complex subunit 2 isoform X1. (554 aa)
LATS1Serine/threonine-protein kinase LATS1 isoform X1. (1138 aa)
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
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