STRINGSTRING
NOCT NOCT FBXW9 FBXW9 CSNK1E CSNK1E OPN5 OPN5 CDK1 CDK1 BHLHE40 BHLHE40 SUV39H1 SUV39H1 LOC102378535 LOC102378535 LOC102382870 LOC102382870 CRY1 CRY1 GHRL GHRL DRD4 DRD4 PPARG PPARG FBXL22 FBXL22 LOC102378108 LOC102378108 UBE3A UBE3A FBXW11 FBXW11 FBXL12 FBXL12 CIPC CIPC PRKAA1 PRKAA1 PPP1CA PPP1CA RORB RORB LOC102372737 LOC102372737 HDAC3 HDAC3 PSPC1 PSPC1 PPARA PPARA FBXL3 FBXL3 THRAP3 THRAP3 ATOH7 ATOH7 CSNK1D CSNK1D NR1D2 NR1D2 OPN4 OPN4 FBXL8 FBXL8 TIMELESS TIMELESS RORC RORC LOC102378662 LOC102378662 ARNTL ARNTL TP53 TP53 LOC102381867 LOC102381867 NONO NONO LOC102374542 LOC102374542 PER1 PER1 SIRT6 SIRT6 FBXW7 FBXW7 LOC102372873 LOC102372873 RORA RORA ROCK2 ROCK2 LOC102382623 LOC102382623 SUV39H2 SUV39H2 LOC102368607 LOC102368607 NR1D1 NR1D1 USP7 USP7 PRKAA2 PRKAA2 DDB1 DDB1 PPARGC1A PPARGC1A CRY2 CRY2 PML PML LOC102383933 LOC102383933 PPP1CC PPP1CC SRRD SRRD TARDBP TARDBP MAPK8 MAPK8 ADCY1 ADCY1 MAPK9 MAPK9 SFPQ SFPQ LOC102373234 LOC102373234 KLF10 KLF10 CRTC1 CRTC1 MTOR MTOR PIWIL2 PIWIL2 LOC102377832 LOC102377832 NPS NPS PER3 PER3 LOC102381255 LOC102381255 PHLPP1 PHLPP1 PPP1CB PPP1CB ATG7 ATG7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NOCTNocturnin isoform X1. (417 aa)
FBXW9F-box/WD repeat-containing protein 9 isoform X1. (457 aa)
CSNK1ECasein kinase I isoform X1; Belongs to the protein kinase superfamily. (417 aa)
OPN5Opsin-5; Belongs to the G-protein coupled receptor 1 family. (350 aa)
CDK1LOW QUALITY PROTEIN: cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (311 aa)
BHLHE40Class E basic helix-loop-helix protein 40. (388 aa)
SUV39H1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (417 aa)
LOC102378535Protein PML-like isoform X1. (852 aa)
LOC102382870Cryptochrome-1-like. (530 aa)
CRY1Cryptochrome-1. (620 aa)
GHRLAppetite-regulating hormone isoform X1. (145 aa)
DRD4D(4) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (375 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (475 aa)
FBXL22F-box and leucine-rich protein 22. (226 aa)
LOC102378108F-box/LRR-repeat protein 21. (435 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (879 aa)
FBXW11F-box/WD repeat-containing protein 11 isoform X1. (531 aa)
FBXL12F-box/LRR-repeat protein 12. (329 aa)
CIPCCLOCK-interacting pacemaker isoform X1. (383 aa)
PRKAA1Non-specific serine/threonine protein kinase. (563 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (301 aa)
RORBNuclear receptor ROR-beta. (461 aa)
LOC102372737LOW QUALITY PROTEIN: period circadian protein homolog 2-like. (1315 aa)
HDAC3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (405 aa)
PSPC1Paraspeckle component 1. (518 aa)
PPARAPeroxisome proliferator-activated receptor alpha isoform X1. (468 aa)
FBXL3F-box/LRR-repeat protein 3. (434 aa)
THRAP3Thyroid hormone receptor-associated protein 3. (962 aa)
ATOH7Protein atonal homolog 7. (151 aa)
CSNK1DCasein kinase I. (442 aa)
NR1D2Nuclear receptor subfamily 1 group D member 2 isoform X2. (588 aa)
OPN4LOW QUALITY PROTEIN: melanopsin; Belongs to the G-protein coupled receptor 1 family. (315 aa)
FBXL8F-box/LRR-repeat protein 8 isoform X1. (382 aa)
TIMELESSLOW QUALITY PROTEIN: protein timeless homolog. (1194 aa)
RORCNuclear receptor ROR-gamma isoform X1. (542 aa)
LOC102378662F-box/WD repeat-containing protein 7-like. (769 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X1. (680 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (397 aa)
LOC102381867F-box/WD repeat-containing protein 1A. (517 aa)
NONOnon-POU domain-containing octamer-binding protein. (460 aa)
LOC102374542Mitogen-activated protein kinase. (464 aa)
PER1Period circadian protein homolog 1 isoform X1. (1311 aa)
SIRT6NAD-dependent protein deacetylase sirtuin-6. (285 aa)
FBXW7F-box/WD repeat-containing protein 7 isoform X1. (762 aa)
LOC102372873Protein PML-like isoform X1. (652 aa)
RORANuclear receptor ROR-alpha. (472 aa)
ROCK2Rho-associated protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1455 aa)
LOC102382623Uncharacterized protein LOC102382623 isoform X1. (195 aa)
SUV39H2Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (451 aa)
LOC102368607F-box/LRR-repeat protein 12-like isoform X1. (309 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1 isoform X1. (637 aa)
USP7Ubiquitin carboxyl-terminal hydrolase 7 isoform X1; Belongs to the peptidase C19 family. (1056 aa)
PRKAA2Non-specific serine/threonine protein kinase. (461 aa)
DDB1DNA damage-binding protein 1. (1130 aa)
PPARGC1APeroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1. (810 aa)
CRY2Cryptochrome-2. (547 aa)
PMLProtein PML. (586 aa)
LOC102383933Melanopsin-like. (546 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (323 aa)
SRRDSRR1-like protein. (247 aa)
TARDBPTAR DNA-binding protein 43. (414 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
ADCY1Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1114 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
SFPQSplicing factor, proline- and glutamine-rich. (460 aa)
LOC102373234Nuclear receptor ROR-beta-like isoform X1. (467 aa)
KLF10Krueppel-like factor 10 isoform X1. (497 aa)
CRTC1CREB-regulated transcription coactivator 1 isoform X1. (611 aa)
MTORSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2551 aa)
PIWIL2Piwi-like protein 2; Belongs to the argonaute family. (969 aa)
LOC102377832Nuclear receptor subfamily 1 group D member 1-like. (516 aa)
NPSNeuropeptide S isoform X2. (105 aa)
PER3LOW QUALITY PROTEIN: period circadian protein homolog 3. (218 aa)
LOC102381255RNA-binding protein 4B isoform X1. (364 aa)
PHLPP1PH domain leucine-rich repeat-containing protein phosphatase 1. (1156 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (326 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (815 aa)
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
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