STRINGSTRING
CREB1 CREB1 SNAI1 SNAI1 MFSD2A MFSD2A DGKQ DGKQ ZBTB20 ZBTB20 LPIN1 LPIN1 BRCA1 BRCA1 NR1D1 NR1D1 SREBF1 SREBF1 SPHK2 SPHK2 ABCG4 ABCG4 SCP2 SCP2 BMP6 BMP6 SREBF2 SREBF2 ABCD1 ABCD1 MTOR MTOR APOA5 APOA5 LOC102370558 LOC102370558 SAMD8 SAMD8 TRIB3 TRIB3 RUSC1 RUSC1 CNEP1R1 CNEP1R1 EIF6 EIF6 GPLD1 GPLD1 IGF2 IGF2 ABCG1 ABCG1 NR1H3 NR1H3 FITM2 FITM2 SCARB1 SCARB1 LPCAT1 LPCAT1 SEC14L5 SEC14L5 LOC102375177 LOC102375177 PIBF1 PIBF1 WDTC1 WDTC1 SPHK1 SPHK1 FGF19 FGF19 PTGS2 PTGS2 CD74 CD74 ASAH1 ASAH1 PRMT3 PRMT3 NR1H2 NR1H2 THRSP THRSP PODN PODN LOC102384045 LOC102384045 SEC14L2 SEC14L2 STARD4 STARD4 ANXA1 ANXA1 SIRT1 SIRT1 SNAI2 SNAI2 LOC102369647 LOC102369647 STAR STAR LPGAT1 LPGAT1 FGF1 FGF1 HTR2B HTR2B FAM3A FAM3A ORMDL3 ORMDL3 LOC102374436 LOC102374436 CGA CGA SLC45A3 SLC45A3 CREBL2 CREBL2 PLA2G6 PLA2G6 SIRT3 SIRT3 DKK3 DKK3 DKKL1 DKKL1 ARMC5 ARMC5 SLC27A1 SLC27A1 APOB APOB REST REST IDH1 IDH1 ADGRF5 ADGRF5 LOC102367890 LOC102367890 LOC102380382 LOC102380382 LPCAT3 LPCAT3 FGFR4 FGFR4 SCAP SCAP DDX20 DDX20 LOC112547978 LOC112547978 LOC102369595 LOC102369595 H6PD H6PD LOC102378738 LOC102378738 LEP LEP NR1H4 NR1H4 APOA4 APOA4 PDGFB PDGFB DAB2 DAB2 ABCD2 ABCD2 WNT4 WNT4 LOC102381973 LOC102381973 SIRT4 SIRT4 HTR2A HTR2A LOC102384651 LOC102384651 CTDNEP1 CTDNEP1 ORMDL1 ORMDL1 ORMDL2 ORMDL2 CYR61 CYR61 ABHD6 ABHD6 LOC102380144 LOC102380144 ENPP7 ENPP7 PPARA PPARA LOC102374014 LOC102374014 LOC102373750 LOC102373750 MLXIPL MLXIPL GPER1 GPER1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CREB1Cyclic AMP-responsive element-binding protein 1. (327 aa)
SNAI1Zinc finger protein SNAI1. (197 aa)
MFSD2ASodium-dependent lysophosphatidylcholine symporter 1 isoform X2. (434 aa)
DGKQDiacylglycerol kinase. (845 aa)
ZBTB20Zinc finger and BTB domain-containing protein 20 isoform X1. (684 aa)
LPIN1Phosphatidate phosphatase LPIN1 isoform X1. (988 aa)
BRCA1LOW QUALITY PROTEIN: breast cancer type 1 susceptibility protein. (1877 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1 isoform X1. (637 aa)
SREBF1Sterol regulatory element-binding protein 1 isoform X2. (1237 aa)
SPHK2Sphingosine kinase 2. (602 aa)
ABCG4ATP-binding cassette sub-family G member 4 isoform X1. (596 aa)
SCP2Non-specific lipid-transfer protein isoform X1; Belongs to the thiolase-like superfamily. Thiolase family. (507 aa)
BMP6Bone morphogenetic protein 6 isoform X1. (320 aa)
SREBF2Sterol regulatory element-binding protein 2 isoform X1. (1096 aa)
ABCD1ATP-binding cassette sub-family D member 1. (848 aa)
MTORSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2551 aa)
APOA5Apolipoprotein A-V isoform X1. (365 aa)
LOC102370558Erlin-2 isoform X1. (356 aa)
SAMD8Sphingomyelin synthase-related protein 1 isoform X1. (415 aa)
TRIB3Tribbles homolog 3. (433 aa)
RUSC1RUN and SH3 domain-containing protein 1. (1198 aa)
CNEP1R1Nuclear envelope phosphatase-regulatory subunit 1. (118 aa)
EIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (184 aa)
GPLD1Phosphatidylinositol-glycan-specific phospholipase D isoform X1. (869 aa)
IGF2Insulin-like growth factor II isoform X2. (268 aa)
ABCG1ATP-binding cassette sub-family G member 1. (677 aa)
NR1H3LOW QUALITY PROTEIN: oxysterols receptor LXR-alpha. (414 aa)
FITM2Fat storage-inducing transmembrane protein 2. (233 aa)
SCARB1Scavenger receptor class B member 1 isoform X1; Belongs to the CD36 family. (473 aa)
LPCAT1Lysophosphatidylcholine acyltransferase 1. (484 aa)
SEC14L5SEC14-like protein 5. (709 aa)
LOC102375177Ectonucleotide pyrophosphatase/phosphodiesterase family member 7-like. (465 aa)
PIBF1Progesterone-induced-blocking factor 1 isoform X1. (761 aa)
WDTC1WD and tetratricopeptide repeats protein 1 isoform X1. (691 aa)
SPHK1Sphingosine kinase 1. (537 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa)
PTGS2Prostaglandin G/H synthase 2. (605 aa)
CD74HLA class II histocompatibility antigen gamma chain. (285 aa)
ASAH1Acid ceramidase; Belongs to the acid ceramidase family. (393 aa)
PRMT3Protein arginine N-methyltransferase 3 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (451 aa)
NR1H2Oxysterols receptor LXR-beta isoform X1. (438 aa)
THRSPThyroid hormone-inducible hepatic protein. (131 aa)
PODNPodocan. (600 aa)
LOC102384045Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa)
SEC14L2SEC14-like protein 2. (409 aa)
STARD4stAR-related lipid transfer protein 4 isoform X1. (207 aa)
ANXA1Annexin. (342 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X1. (557 aa)
SNAI2Zinc finger protein SNAI2. (268 aa)
LOC102369647Alpha-1-antitrypsin-like protein CM55-MM; Belongs to the serpin family. (423 aa)
STARSteroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (287 aa)
LPGAT1acyl-CoA:lysophosphatidylglycerol acyltransferase 1. (369 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
HTR2B5-hydroxytryptamine receptor 2B isoform X1. (482 aa)
FAM3AProtein FAM3A isoform X1. (232 aa)
ORMDL3ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
LOC102374436Nuclear receptor subfamily 0 group B member 2-like. (303 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa)
SLC45A3Solute carrier family 45 member 3. (567 aa)
CREBL2cAMP-responsive element-binding protein-like 2 isoform X1. (121 aa)
PLA2G685/88 kDa calcium-independent phospholipase A2 isoform X1. (859 aa)
SIRT3NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (390 aa)
DKK3Dickkopf-related protein 3. (290 aa)
DKKL1Dickkopf-like protein 1 isoform X1. (415 aa)
ARMC5Armadillo repeat-containing protein 5. (1001 aa)
SLC27A1Long-chain fatty acid transport protein 1 isoform X1. (646 aa)
APOBApolipoprotein B-100. (3654 aa)
RESTRE1-silencing transcription factor. (894 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (415 aa)
ADGRF5Adhesion G protein-coupled receptor F5 isoform X1; Belongs to the G-protein coupled receptor 2 family. (1283 aa)
LOC102367890Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (348 aa)
LOC102380382long-chain-fatty-acid--CoA ligase 3. (259 aa)
LPCAT3Lysophospholipid acyltransferase 5 isoform X1; Belongs to the membrane-bound acyltransferase family. (514 aa)
FGFR4Fibroblast growth factor receptor 4 isoform X1. (647 aa)
SCAPSterol regulatory element-binding protein cleavage-activating protein isoform X1. (1342 aa)
DDX20Probable ATP-dependent RNA helicase DDX20; Belongs to the DEAD box helicase family. (778 aa)
LOC112547978Interleukin-1. (241 aa)
LOC102369595Interleukin-1; Belongs to the IL-1 family. (279 aa)
H6PDLOW QUALITY PROTEIN: GDH/6PGL endoplasmic bifunctional protein. (793 aa)
LOC102378738Tumor necrosis factor. (231 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (165 aa)
NR1H4Bile acid receptor. (465 aa)
APOA4Apolipoprotein A-IV isoform X1. (396 aa)
PDGFBPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (276 aa)
DAB2Disabled homolog 2. (703 aa)
ABCD2ATP-binding cassette sub-family D member 2. (695 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (296 aa)
LOC102381973Fatty acid-binding protein, epidermal. (112 aa)
SIRT4NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. (315 aa)
HTR2A5-hydroxytryptamine receptor 2A. (470 aa)
LOC102384651Apolipoprotein B-100-like. (991 aa)
CTDNEP1CTD nuclear envelope phosphatase 1 isoform X1. (244 aa)
ORMDL1ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
ORMDL2ORM1-like protein; Negative regulator of sphingolipid synthesis. (194 aa)
CYR61Protein CYR61. (374 aa)
ABHD6Monoacylglycerol lipase ABHD6. (337 aa)
LOC102380144long-chain-fatty-acid--CoA ligase 3-like. (453 aa)
ENPP7Ectonucleotide pyrophosphatase/phosphodiesterase family member 7. (399 aa)
PPARAPeroxisome proliferator-activated receptor alpha isoform X1. (468 aa)
LOC102374014Erlin-1 isoform X3. (294 aa)
LOC102373750Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (512 aa)
MLXIPLCarbohydrate-responsive element-binding protein. (895 aa)
GPER1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (358 aa)
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
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