STRINGSTRING
GJA5 GJA5 NPRL3 NPRL3 EDNRA EDNRA PRDM1 PRDM1 HAND2 HAND2 ANGPTL3 ANGPTL3 SEC24B SEC24B EDN1 EDN1 FKBP10 FKBP10 APOB APOB ADGRF5 ADGRF5 ENG ENG JAG1 JAG1 SRF SRF LOC102384651 LOC102384651 BMPR2 BMPR2 TGFBR1 TGFBR1 PKD2 PKD2 ZNF683 ZNF683 STRA6 STRA6 HPGD HPGD MYOCD MYOCD DLL4 DLL4 HOXA13 HOXA13 ARID2 ARID2 NF1 NF1 SMAD7 SMAD7 ACVRL1 ACVRL1 FGF8 FGF8 NOTCH3 NOTCH3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (399 aa)
NPRL3GATOR complex protein NPRL3 isoform X1. (491 aa)
EDNRAEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (417 aa)
PRDM1PR domain zinc finger protein 1 isoform X1. (816 aa)
HAND2Heart- and neural crest derivatives-expressed protein 2. (116 aa)
ANGPTL3Angiopoietin-related protein 3. (462 aa)
SEC24BProtein transport protein Sec24B. (1193 aa)
EDN1Endothelin-1. (200 aa)
FKBP10Peptidylprolyl isomerase. (564 aa)
APOBApolipoprotein B-100. (3654 aa)
ADGRF5Adhesion G protein-coupled receptor F5 isoform X1; Belongs to the G-protein coupled receptor 2 family. (1283 aa)
ENGEndoglin. (667 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1177 aa)
SRFSerum response factor isoform X1. (412 aa)
LOC102384651Apolipoprotein B-100-like. (991 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1041 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (440 aa)
PKD2Polycystin-2 isoform X1. (766 aa)
ZNF683Tissue-resident T-cell transcription regulator protein ZNF683. (577 aa)
STRA6Receptor for retinol uptake STRA6. (691 aa)
HPGD15-hydroxyprostaglandin dehydrogenase [NAD(+)]; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (252 aa)
MYOCDMyocardin isoform X1. (934 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (615 aa)
HOXA13LOW QUALITY PROTEIN: homeobox protein Hox-A13. (316 aa)
ARID2AT-rich interactive domain-containing protein 2 isoform X1. (1862 aa)
NF1Neurofibromin. (2861 aa)
SMAD7Mothers against decapentaplegic homolog. (284 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (523 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa)
NOTCH3Neurogenic locus notch homolog protein 3. (2361 aa)
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
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