16 items (Alligator sinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AP2A1	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (969 aa)
	ANKRA2	Ankyrin repeat family A protein 2 isoform X1. (322 aa)
	LANCL1	lanC-like protein 1. (399 aa)
	HSP90B1	Endoplasmin. (427 aa)
	LDLRAP1	Low density lipoprotein receptor adapter protein 1 isoform X1. (332 aa)
	APOB	Apolipoprotein B-100. (3654 aa)
	MESD	LRP chaperone MESD. (182 aa)
	LOC102384651	Apolipoprotein B-100-like. (991 aa)
	APOE	Apolipoprotein E isoform X1. (252 aa)
	DAB2	Disabled homolog 2. (703 aa)
	CLTC	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1664 aa)
	APOA5	Apolipoprotein A-V isoform X1. (365 aa)
	CLTCL1	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1684 aa)
	LRPAP1	Alpha-2-macroglobulin receptor-associated protein. (328 aa)
	PCSK9	Proprotein convertase subtilisin/kexin type 9. (666 aa)
	LOC102386157	Endoplasmin-like. (369 aa)

Your Current Organism:

Alligator sinensis

NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP2A1	APOB	A0A3Q0G0P4	A0A1U7SB35	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Apolipoprotein B-100.	0.444
AP2A1	CLTC	A0A3Q0G0P4	A0A3Q0H3P1	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.907
AP2A1	CLTCL1	A0A3Q0G0P4	A0A1U8D9N5	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.907
AP2A1	DAB2	A0A3Q0G0P4	A0A1U8D9B0	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Disabled homolog 2.	0.640
AP2A1	LDLRAP1	A0A3Q0G0P4	A0A1U7RUU8	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Low density lipoprotein receptor adapter protein 1 isoform X1.	0.657
AP2A1	LOC102384651	A0A3Q0G0P4	A0A1U7SVD5	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Apolipoprotein B-100-like.	0.444
APOA5	APOB	A0A3Q0H6S2	A0A1U7SB35	Apolipoprotein A-V isoform X1.	Apolipoprotein B-100.	0.579
APOA5	APOE	A0A3Q0H6S2	A0A1U7SXQ0	Apolipoprotein A-V isoform X1.	Apolipoprotein E isoform X1.	0.423
APOA5	LOC102384651	A0A3Q0H6S2	A0A1U7SVD5	Apolipoprotein A-V isoform X1.	Apolipoprotein B-100-like.	0.579
APOB	AP2A1	A0A1U7SB35	A0A3Q0G0P4	Apolipoprotein B-100.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.444
APOB	APOA5	A0A1U7SB35	A0A3Q0H6S2	Apolipoprotein B-100.	Apolipoprotein A-V isoform X1.	0.579
APOB	APOE	A0A1U7SB35	A0A1U7SXQ0	Apolipoprotein B-100.	Apolipoprotein E isoform X1.	0.791
APOB	DAB2	A0A1U7SB35	A0A1U8D9B0	Apolipoprotein B-100.	Disabled homolog 2.	0.557
APOB	HSP90B1	A0A1U7SB35	A0A1U7RQW0	Apolipoprotein B-100.	Endoplasmin.	0.415
APOB	LDLRAP1	A0A1U7SB35	A0A1U7RUU8	Apolipoprotein B-100.	Low density lipoprotein receptor adapter protein 1 isoform X1.	0.701
APOB	LOC102384651	A0A1U7SB35	A0A1U7SVD5	Apolipoprotein B-100.	Apolipoprotein B-100-like.	0.907
APOB	LOC102386157	A0A1U7SB35	A0A3Q0FWJ5	Apolipoprotein B-100.	Endoplasmin-like.	0.415
APOB	PCSK9	A0A1U7SB35	A0A3Q0GWA6	Apolipoprotein B-100.	Proprotein convertase subtilisin/kexin type 9.	0.535
APOE	APOA5	A0A1U7SXQ0	A0A3Q0H6S2	Apolipoprotein E isoform X1.	Apolipoprotein A-V isoform X1.	0.423
APOE	APOB	A0A1U7SXQ0	A0A1U7SB35	Apolipoprotein E isoform X1.	Apolipoprotein B-100.	0.791