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MREG MREG LOC102387334 LOC102387334 PSEN1 PSEN1 WDR11 WDR11 MYO6 MYO6 LOC102383954 LOC102383954 NDE1 NDE1 PEF1 PEF1 KIF5B KIF5B EXOC6 EXOC6 LOC102372150 LOC102372150 SNAPIN SNAPIN YKT6 YKT6 LOC102370720 LOC102370720 LOC102378719 LOC102378719 ARFGAP2 ARFGAP2 LOC102378555 LOC102378555 KIF5A KIF5A MYO1C MYO1C LOC102375640 LOC102375640 CTNNB1 CTNNB1 LOC102376880 LOC102376880 KLHL12 KLHL12 LOC102384870 LOC102384870 BLOC1S1 BLOC1S1 ARFGAP3 ARFGAP3 BLOC1S6 BLOC1S6 EXOC4 EXOC4 LOC102387293 LOC102387293 CEP19 CEP19 TFG TFG MYO1F MYO1F TBC1D23 TBC1D23 MYO5A MYO5A RAB11A RAB11A FYCO1 FYCO1 EXOC6B EXOC6B TRAK2 TRAK2 LOC102374573 LOC102374573 STARD3NL STARD3NL LOC102371683 LOC102371683 HAP1 HAP1 MYO7B MYO7B MYO19 MYO19 MYO1G MYO1G LOC102382505 LOC102382505 TESK1 TESK1 CCDC186 CCDC186 TMEM230 TMEM230 AP3D1 AP3D1 MYO1B MYO1B AP3B2 AP3B2 MYO1A MYO1A PICALM PICALM TRIP11 TRIP11 BICDL2 BICDL2 DCTN1 DCTN1 SPG11 SPG11 LOC112548499 LOC112548499 WIPI1 WIPI1 MYO5C MYO5C MYO15B MYO15B RASGRP1 RASGRP1 TANC2 TANC2 LOC112549705 LOC112549705 FNBP1L FNBP1L TMED10 TMED10 LOC102383202 LOC102383202 STARD3 STARD3 MYO1E MYO1E CLASP2 CLASP2 AP1AR AP1AR RAB11B RAB11B LOC112550422 LOC112550422 MYO1D MYO1D DTNBP1 DTNBP1 SHROOM2 SHROOM2 GBF1 GBF1 BLOC1S5 BLOC1S5 CLASP1 CLASP1 FAM91A1 FAM91A1 COPS5 COPS5 BLOC1S3 BLOC1S3 SYT11 SYT11 TRAK1 TRAK1 AP3M1 AP3M1 BLOC1S4 BLOC1S4 SYNJ1 SYNJ1 SCRIB SCRIB SNAP91 SNAP91 HTT HTT PREB PREB TRAPPC13 TRAPPC13 KIF5C KIF5C LOC102388471 LOC102388471 PAFAH1B1 PAFAH1B1 CUNH17orf75 CUNH17orf75 MYO1H MYO1H BLOC1S2 BLOC1S2 LOC102370793 LOC102370793 DYNC1H1 DYNC1H1 LRRC1 LRRC1 PDCD6 PDCD6 SYT4 SYT4 CUL3 CUL3 FBXW11 FBXW11 LOC102383786 LOC102383786 AP3M2 AP3M2 MYO7A MYO7A SEC16A SEC16A GPR143 GPR143
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MREGMelanoregulin. (250 aa)
LOC102387334BICD family-like cargo adapter 1. (425 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (468 aa)
WDR11WD repeat-containing protein 11. (1192 aa)
MYO6Unconventional myosin-VI isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1285 aa)
LOC102383954BICD family-like cargo adapter 1. (89 aa)
NDE1Nuclear distribution protein nudE homolog 1. (346 aa)
PEF1Peflin. (284 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (966 aa)
EXOC6Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (795 aa)
LOC102372150Unconventional myosin-XV. (1580 aa)
SNAPINSNARE-associated protein Snapin. (78 aa)
YKT6Synaptobrevin homolog YKT6 isoform X1; Belongs to the synaptobrevin family. (244 aa)
LOC102370720Factor VIII intron 22 protein-like. (184 aa)
LOC102378719Unconventional myosin-Vb. (550 aa)
ARFGAP2ADP-ribosylation factor GTPase-activating protein 2 isoform X1. (540 aa)
LOC102378555Unconventional myosin-Ie-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1095 aa)
KIF5AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (891 aa)
MYO1CUnconventional myosin-Ic isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1078 aa)
LOC102375640Unconventional myosin-Vb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1297 aa)
CTNNB1Catenin beta-1. (784 aa)
LOC102376880Unconventional myosin-Vb-like isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1743 aa)
KLHL12Kelch-like protein 12 isoform X1. (564 aa)
LOC102384870Integrin alpha-4; Belongs to the integrin alpha chain family. (708 aa)
BLOC1S1Biogenesis of lysosome-related organelles complex 1 subunit 1. (125 aa)
ARFGAP3ADP-ribosylation factor GTPase-activating protein 3 isoform X1. (534 aa)
BLOC1S6Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (171 aa)
EXOC4Exocyst complex component 4. (974 aa)
LOC102387293Ras-related protein Rab-11A-like. (216 aa)
CEP19Centrosomal protein of 19 kDa. (163 aa)
TFGProtein TFG. (396 aa)
MYO1FUnconventional myosin-If; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1077 aa)
TBC1D23TBC1 domain family member 23 isoform X1. (690 aa)
MYO5AUnconventional myosin-Va isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1881 aa)
RAB11ARas-related protein Rab-11A. (238 aa)
FYCO1FYVE and coiled-coil domain-containing protein 1 isoform X1. (1547 aa)
EXOC6BExocyst complex component 6B. (359 aa)
TRAK2Trafficking kinesin-binding protein 2 isoform X1. (920 aa)
LOC102374573AP-3 complex subunit beta-1. (884 aa)
STARD3NLSTARD3 N-terminal-like protein. (234 aa)
LOC102371683Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (1061 aa)
HAP1Huntingtin-associated protein 1. (885 aa)
MYO7BUnconventional myosin-VIIb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2142 aa)
MYO19Unconventional myosin-XIX isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (970 aa)
MYO1GUnconventional myosin-Ig; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1032 aa)
LOC102382505Phosphatidylinositol-binding clathrin assembly protein-like isoform X1. (638 aa)
TESK1Dual specificity testis-specific protein kinase 1. (636 aa)
CCDC186Coiled-coil domain-containing protein 186 isoform X1. (926 aa)
TMEM230Transmembrane protein 230. (120 aa)
AP3D1AP-3 complex subunit delta-1 isoform X1. (1213 aa)
MYO1BUnconventional myosin-Ib; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1103 aa)
AP3B2AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1153 aa)
MYO1ALOW QUALITY PROTEIN: unconventional myosin-Ia; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1058 aa)
PICALMPhosphatidylinositol-binding clathrin assembly protein isoform X1. (711 aa)
TRIP11Thyroid receptor-interacting protein 11 isoform X1. (1989 aa)
BICDL2BICD family-like cargo adapter 2. (460 aa)
DCTN1Dynactin subunit 1 isoform X1. (1147 aa)
SPG11Spatacsin isoform X1. (2418 aa)
LOC112548499Dynactin subunit 1-like. (151 aa)
WIPI1WD repeat domain phosphoinositide-interacting protein 1 isoform X2. (413 aa)
MYO5CUnconventional myosin-Vc; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1810 aa)
MYO15BMyosin XVB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (3246 aa)
RASGRP1RAS guanyl-releasing protein 1 isoform X1. (744 aa)
TANC2Protein TANC2 isoform X1. (2072 aa)
LOC112549705Synaptotagmin-2-like isoform X1. (505 aa)
FNBP1LFormin-binding protein 1-like isoform X5. (610 aa)
TMED10Transmembrane emp24 domain-containing protein 10; Belongs to the EMP24/GP25L family. (119 aa)
LOC102383202AP-3 complex subunit beta-1-like isoform X1. (362 aa)
STARD3stAR-related lipid transfer protein 3. (444 aa)
MYO1EUnconventional myosin-Ie isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1086 aa)
CLASP2CLIP-associating protein 2 isoform X1. (1440 aa)
AP1ARAP-1 complex-associated regulatory protein isoform X1. (286 aa)
RAB11BRas-related protein Rab-11B. (206 aa)
LOC112550422Uncharacterized protein LOC112550422. (263 aa)
MYO1DUnconventional myosin-Id; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (986 aa)
DTNBP1Dysbindin isoform X1. (379 aa)
SHROOM2Protein Shroom2 isoform X1. (1733 aa)
GBF1Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 isoform X1. (1892 aa)
BLOC1S5Biogenesis of lysosome-related organelles complex 1 subunit 5; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). (168 aa)
CLASP1CLIP-associating protein 1 isoform X1. (1497 aa)
FAM91A1Protein FAM91A1 isoform X1. (849 aa)
COPS5COP9 signalosome complex subunit 5 isoform X1. (275 aa)
BLOC1S3LOW QUALITY PROTEIN: biogenesis of lysosome-related organelles complex 1 subunit 3. (167 aa)
SYT11Synaptotagmin-11 isoform X1. (373 aa)
TRAK1Trafficking kinesin-binding protein 1 isoform X1. (1107 aa)
AP3M1LOW QUALITY PROTEIN: AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (427 aa)
BLOC1S4Biogenesis of lysosome-related organelles complex 1 subunit 4. (182 aa)
SYNJ1Synaptojanin-1. (1589 aa)
SCRIBProtein scribble homolog. (1923 aa)
SNAP91Clathrin coat assembly protein AP180 isoform X1. (952 aa)
HTTHuntingtin isoform X1. (3118 aa)
PREBProlactin regulatory element-binding protein. (429 aa)
TRAPPC13Trafficking protein particle complex subunit 13 isoform X1. (422 aa)
KIF5CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (899 aa)
LOC102388471Exocyst complex component 6B. (513 aa)
PAFAH1B1Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (410 aa)
CUNH17orf75Protein Njmu-R1. (385 aa)
MYO1HUnconventional myosin-Ih isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1055 aa)
BLOC1S2Biogenesis of lysosome-related organelles complex 1 subunit 2. (99 aa)
LOC102370793Melanoregulin-like. (242 aa)
DYNC1H1Cytoplasmic dynein 1 heavy chain 1. (4600 aa)
LRRC1Leucine-rich repeat-containing protein 1. (443 aa)
PDCD6Programmed cell death protein 6 isoform X2. (173 aa)
SYT4Synaptotagmin-4. (425 aa)
CUL3Cullin-3 isoform X1; Belongs to the cullin family. (746 aa)
FBXW11F-box/WD repeat-containing protein 11 isoform X1. (531 aa)
LOC102383786Integrin alpha-4-like. (315 aa)
AP3M2LOW QUALITY PROTEIN: AP-3 complex subunit mu-2; Belongs to the adaptor complexes medium subunit family. (393 aa)
MYO7AUnconventional myosin-VIIa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2206 aa)
SEC16AProtein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (2471 aa)
GPR143G-protein coupled receptor 143. (403 aa)
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
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