37 items (Alligator sinensis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	TNFAIP3	Tumor necrosis factor alpha-induced protein 3 isoform X1. (817 aa)
	GGA3	ADP-ribosylation factor-binding protein GGA3. (682 aa)
	CACNG8	Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (342 aa)
	VPS25	Vacuolar protein-sorting-associated protein 25. (267 aa)
	CACNG7	Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
	VPS36	Vacuolar protein-sorting-associated protein 36. (383 aa)
	CACNG5	Voltage-dependent calcium channel gamma-5 subunit. (279 aa)
	SMURF1	E3 ubiquitin-protein ligase SMURF1. (718 aa)
	VPS41	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (854 aa)
	SNF8	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
	MON1A	Vacuolar fusion protein MON1 homolog A isoform X1. (549 aa)
	CACNG2	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (313 aa)
	CACNG3	Voltage-dependent calcium channel gamma-3 subunit. (259 aa)
	VPS28	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (219 aa)
	VPS13A	Vacuolar protein sorting-associated protein 13A. (3206 aa)
	STAM	Signal transducing adapter molecule 1. (542 aa)
	SORT1	Sortilin. (753 aa)
	AP3D1	AP-3 complex subunit delta-1 isoform X1. (1213 aa)
	PTPN23	Tyrosine-protein phosphatase non-receptor type 23. (1689 aa)
	SCARB2	Lysosome membrane protein 2 isoform X1; Belongs to the CD36 family. (429 aa)
	HGS	Hepatocyte growth factor-regulated tyrosine kinase substrate. (651 aa)
	RNF215	RING finger protein 215. (233 aa)
	LOC102388478	Vacuolar fusion protein MON1 homolog B. (621 aa)
	PIK3R4	Phosphoinositide 3-kinase regulatory subunit 4 isoform X1. (1382 aa)
	CACNG4	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (286 aa)
	VPS13D	Vacuolar protein sorting-associated protein 13D isoform X1. (4390 aa)
	GNPTAB	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta. (1483 aa)
	VPS37B	Vacuolar protein sorting-associated protein 37B. (267 aa)
	SORL1	Sortilin-related receptor isoform X1. (2109 aa)
	SNX16	Sorting nexin-16 isoform X1. (382 aa)
	VPS37A	Vacuolar protein sorting-associated protein 37A isoform X1. (333 aa)
	VPS37C	Vacuolar protein sorting-associated protein 37C. (116 aa)
	LAMP2	Lysosome-associated membrane glycoprotein 2. (380 aa)
	VPS13C	Vacuolar protein sorting-associated protein 13C isoform X1. (3738 aa)
	VPS37D	Vacuolar protein sorting-associated protein 37D isoform X1. (305 aa)
	GCC2	GRIP and coiled-coil domain-containing protein 2 isoform X1. (1737 aa)
	M6PR	Cation-dependent mannose-6-phosphate receptor. (283 aa)

Your Current Organism:

Alligator sinensis

NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP3D1	HGS	A0A1U8DWE7	A0A3Q0FPD8	AP-3 complex subunit delta-1 isoform X1.	Hepatocyte growth factor-regulated tyrosine kinase substrate.	0.476
AP3D1	SORL1	A0A1U8DWE7	A0A3Q0GCD1	AP-3 complex subunit delta-1 isoform X1.	Sortilin-related receptor isoform X1.	0.665
AP3D1	STAM	A0A1U8DWE7	A0A1U7STQ2	AP-3 complex subunit delta-1 isoform X1.	Signal transducing adapter molecule 1.	0.406
AP3D1	VPS41	A0A1U8DWE7	A0A1U7RUF7	AP-3 complex subunit delta-1 isoform X1.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.766
GCC2	GGA3	A0A3Q0HBC4	A0A1U7R6X2	GRIP and coiled-coil domain-containing protein 2 isoform X1.	ADP-ribosylation factor-binding protein GGA3.	0.430
GCC2	M6PR	A0A3Q0HBC4	A0A3Q0HET7	GRIP and coiled-coil domain-containing protein 2 isoform X1.	Cation-dependent mannose-6-phosphate receptor.	0.632
GGA3	GCC2	A0A1U7R6X2	A0A3Q0HBC4	ADP-ribosylation factor-binding protein GGA3.	GRIP and coiled-coil domain-containing protein 2 isoform X1.	0.430
GGA3	HGS	A0A1U7R6X2	A0A3Q0FPD8	ADP-ribosylation factor-binding protein GGA3.	Hepatocyte growth factor-regulated tyrosine kinase substrate.	0.400
GGA3	M6PR	A0A1U7R6X2	A0A3Q0HET7	ADP-ribosylation factor-binding protein GGA3.	Cation-dependent mannose-6-phosphate receptor.	0.915
GGA3	SORT1	A0A1U7R6X2	A0A1U8DJM7	ADP-ribosylation factor-binding protein GGA3.	Sortilin.	0.515
HGS	AP3D1	A0A3Q0FPD8	A0A1U8DWE7	Hepatocyte growth factor-regulated tyrosine kinase substrate.	AP-3 complex subunit delta-1 isoform X1.	0.476
HGS	GGA3	A0A3Q0FPD8	A0A1U7R6X2	Hepatocyte growth factor-regulated tyrosine kinase substrate.	ADP-ribosylation factor-binding protein GGA3.	0.400
HGS	PTPN23	A0A3Q0FPD8	A0A1U8DXS2	Hepatocyte growth factor-regulated tyrosine kinase substrate.	Tyrosine-protein phosphatase non-receptor type 23.	0.745
HGS	SMURF1	A0A3Q0FPD8	A0A1U7RU75	Hepatocyte growth factor-regulated tyrosine kinase substrate.	E3 ubiquitin-protein ligase SMURF1.	0.474
HGS	SNF8	A0A3Q0FPD8	A0A1U7S2P5	Hepatocyte growth factor-regulated tyrosine kinase substrate.	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	0.861
HGS	STAM	A0A3Q0FPD8	A0A1U7STQ2	Hepatocyte growth factor-regulated tyrosine kinase substrate.	Signal transducing adapter molecule 1.	0.998
HGS	VPS25	A0A3Q0FPD8	A0A1U7RC12	Hepatocyte growth factor-regulated tyrosine kinase substrate.	Vacuolar protein-sorting-associated protein 25.	0.885
HGS	VPS28	A0A3Q0FPD8	A0A1U7SID2	Hepatocyte growth factor-regulated tyrosine kinase substrate.	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.895
HGS	VPS36	A0A3Q0FPD8	A0A1U7RN58	Hepatocyte growth factor-regulated tyrosine kinase substrate.	Vacuolar protein-sorting-associated protein 36.	0.833
HGS	VPS37A	A0A3Q0FPD8	A0A3Q0GTW5	Hepatocyte growth factor-regulated tyrosine kinase substrate.	Vacuolar protein sorting-associated protein 37A isoform X1.	0.643