STRINGSTRING
RB1 RB1 LOC102384045 LOC102384045 PAX6 PAX6 HAND2 HAND2 CTNNB1 CTNNB1 GTF2B GTF2B TGFB1 TGFB1 EP300 EP300 DDRGK1 DDRGK1 FAM129B FAM129B GATA3 GATA3 TRAF6 TRAF6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RB1Retinoblastoma-associated protein isoform X1. (905 aa)
LOC102384045Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa)
PAX6Paired box protein Pax-6 isoform X1. (436 aa)
HAND2Heart- and neural crest derivatives-expressed protein 2. (116 aa)
CTNNB1Catenin beta-1. (784 aa)
GTF2BTranscription initiation factor IIB. (316 aa)
TGFB1Transforming growth factor beta-1. (235 aa)
EP300Histone acetyltransferase p300 isoform X1. (2149 aa)
DDRGK1DDRGK domain-containing protein 1. (242 aa)
FAM129BNiban-like protein 1. (807 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3. (385 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
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