12 items (Alligator sinensis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	RB1	Retinoblastoma-associated protein isoform X1. (905 aa)
	LOC102384045	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa)
	PAX6	Paired box protein Pax-6 isoform X1. (436 aa)
	HAND2	Heart- and neural crest derivatives-expressed protein 2. (116 aa)
	CTNNB1	Catenin beta-1. (784 aa)
	GTF2B	Transcription initiation factor IIB. (316 aa)
	TGFB1	Transforming growth factor beta-1. (235 aa)
	EP300	Histone acetyltransferase p300 isoform X1. (2149 aa)
	DDRGK1	DDRGK domain-containing protein 1. (242 aa)
	FAM129B	Niban-like protein 1. (807 aa)
	GATA3	Trans-acting T-cell-specific transcription factor GATA-3. (385 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)

Your Current Organism:

Alligator sinensis

NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTNNB1	EP300	A0A1U7S8W7	A0A1U8D7N2	Catenin beta-1.	Histone acetyltransferase p300 isoform X1.	0.961
CTNNB1	TGFB1	A0A1U7S8W7	A0A1U7SS54	Catenin beta-1.	Transforming growth factor beta-1.	0.538
EP300	CTNNB1	A0A1U8D7N2	A0A1U7S8W7	Histone acetyltransferase p300 isoform X1.	Catenin beta-1.	0.961
EP300	GATA3	A0A1U8D7N2	A0A3Q0HAJ7	Histone acetyltransferase p300 isoform X1.	Trans-acting T-cell-specific transcription factor GATA-3.	0.790
EP300	GTF2B	A0A1U8D7N2	A0A1U7SIB4	Histone acetyltransferase p300 isoform X1.	Transcription initiation factor IIB.	0.691
EP300	PAX6	A0A1U8D7N2	A0A1U7RYY7	Histone acetyltransferase p300 isoform X1.	Paired box protein Pax-6 isoform X1.	0.573
EP300	RB1	A0A1U8D7N2	A0A3Q0H679	Histone acetyltransferase p300 isoform X1.	Retinoblastoma-associated protein isoform X1.	0.436
EP300	TGFB1	A0A1U8D7N2	A0A1U7SS54	Histone acetyltransferase p300 isoform X1.	Transforming growth factor beta-1.	0.550
GATA3	EP300	A0A3Q0HAJ7	A0A1U8D7N2	Trans-acting T-cell-specific transcription factor GATA-3.	Histone acetyltransferase p300 isoform X1.	0.790
GATA3	HAND2	A0A3Q0HAJ7	A0A1U7S0H7	Trans-acting T-cell-specific transcription factor GATA-3.	Heart- and neural crest derivatives-expressed protein 2.	0.572
GATA3	LOC102384045	A0A3Q0HAJ7	A0A1U7RPI8	Trans-acting T-cell-specific transcription factor GATA-3.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.582
GTF2B	EP300	A0A1U7SIB4	A0A1U8D7N2	Transcription initiation factor IIB.	Histone acetyltransferase p300 isoform X1.	0.691
HAND2	GATA3	A0A1U7S0H7	A0A3Q0HAJ7	Heart- and neural crest derivatives-expressed protein 2.	Trans-acting T-cell-specific transcription factor GATA-3.	0.572
HAND2	LOC102384045	A0A1U7S0H7	A0A1U7RPI8	Heart- and neural crest derivatives-expressed protein 2.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.459
LOC102384045	GATA3	A0A1U7RPI8	A0A3Q0HAJ7	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Trans-acting T-cell-specific transcription factor GATA-3.	0.582
LOC102384045	HAND2	A0A1U7RPI8	A0A1U7S0H7	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Heart- and neural crest derivatives-expressed protein 2.	0.459
LOC102384045	TGFB1	A0A1U7RPI8	A0A1U7SS54	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Transforming growth factor beta-1.	0.549
LOC102384045	TRAF6	A0A1U7RPI8	A0A1U7RAW4	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.467
PAX6	EP300	A0A1U7RYY7	A0A1U8D7N2	Paired box protein Pax-6 isoform X1.	Histone acetyltransferase p300 isoform X1.	0.573
RB1	EP300	A0A3Q0H679	A0A1U8D7N2	Retinoblastoma-associated protein isoform X1.	Histone acetyltransferase p300 isoform X1.	0.436