(47 nodes) Phagocytic vesicle network (Alligator sinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RAB32	Ras-related protein Rab-32. (221 aa)
	RAB31	Ras-related protein Rab-31. (195 aa)
	INPP5B	Type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X3. (921 aa)
	LOC112551641	Uncharacterized protein LOC112551641. (285 aa)
	EMILIN2	EMILIN-2. (1006 aa)
	APPL1	DCC-interacting protein 13-alpha isoform X1. (669 aa)
	SYK	Tyrosine-protein kinase SYK isoform X1. (658 aa)
	SYT11	Synaptotagmin-11 isoform X1. (373 aa)
	PIKFYVE	1-phosphatidylinositol 3-phosphate 5-kinase. (2126 aa)
	OCRL	Inositol polyphosphate 5-phosphatase OCRL-1 isoform X1. (836 aa)
	SYT7	Synaptotagmin-7. (679 aa)
	TLR8	Toll-like receptor 8 isoform X1; Belongs to the Toll-like receptor family. (1090 aa)
	CORO1C	Coronin; Belongs to the WD repeat coronin family. (951 aa)
	LOC112549188	Uncharacterized protein LOC112549188 isoform X1. (247 aa)
	LOC112548964	Uncharacterized protein LOC112548964. (433 aa)
	LAMP1	Lysosome-associated membrane glycoprotein 1 isoform X1. (427 aa)
	LOC112548285	Uncharacterized protein LOC112548285. (484 aa)
	LOC112548464	Uncharacterized protein LOC112548464 isoform X1. (266 aa)
	PIP4P1	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (197 aa)
	LOC112548287	Toll-like receptor 10 isoform X1. (243 aa)
	LOC112548286	Uncharacterized protein LOC112548286. (456 aa)
	CORO6	Coronin; Belongs to the WD repeat coronin family. (659 aa)
	UNC93B1	Protein unc-93 homolog B1. (578 aa)
	PIP4P2	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (266 aa)
	LOC102384063	Toll-like receptor 2; Belongs to the Toll-like receptor family. (837 aa)
	LOC102382670	Macrophage-expressed gene 1 protein-like. (718 aa)
	RAB39A	Ras-related protein Rab-39A. (213 aa)
	CORO1B	Coronin; Belongs to the WD repeat coronin family. (484 aa)
	LOC102371494	Toll-like receptor 1. (652 aa)
	MPEG1	Macrophage-expressed gene 1 protein. (721 aa)
	LOC102375729	Phospholipase A(2). (137 aa)
	LOC102375359	Toll-like receptor 8. (1040 aa)
	RAB20	Ras-related protein Rab-20. (234 aa)
	LOC102368346	Toll-like receptor 2 type-2; Belongs to the Toll-like receptor family. (793 aa)
	TLR2	Toll-like receptor 2; Belongs to the Toll-like receptor family. (784 aa)
	RAB38	Ras-related protein Rab-38. (212 aa)
	TLR7	Toll-like receptor 7; Belongs to the Toll-like receptor family. (1050 aa)
	LOC102383113	Toll-like receptor 2. (875 aa)
	RAB9A	Ras-related protein Rab-9A. (201 aa)
	APPL2	DCC-interacting protein 13-beta isoform X1. (659 aa)
	RAB22A	Ras-related protein Rab-22A. (194 aa)
	LOC102373745	Toll-like receptor 1; Belongs to the Toll-like receptor family. (801 aa)
	RAB23	Ras-related protein Rab-23. (237 aa)
	ANXA3	Annexin. (323 aa)
	RAB7B	Ras-related protein Rab-7b. (207 aa)
	RAB14	Ras-related protein Rab-14. (215 aa)
	RAB9B	Ras-related protein Rab-9B. (201 aa)

Your Current Organism:

Alligator sinensis

NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APPL1	APPL2	A0A3Q0HAC2	A0A1U7S4N5	DCC-interacting protein 13-alpha isoform X1.	DCC-interacting protein 13-beta isoform X1.	0.992
APPL1	INPP5B	A0A3Q0HAC2	A0A3Q0HFQ8	DCC-interacting protein 13-alpha isoform X1.	Type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X3.	0.555
APPL1	LOC112548464	A0A3Q0HAC2	A0A3Q0FS01	DCC-interacting protein 13-alpha isoform X1.	Uncharacterized protein LOC112548464 isoform X1.	0.661
APPL1	LOC112549188	A0A3Q0HAC2	A0A3Q0G133	DCC-interacting protein 13-alpha isoform X1.	Uncharacterized protein LOC112549188 isoform X1.	0.546
APPL1	OCRL	A0A3Q0HAC2	A0A3Q0H2B5	DCC-interacting protein 13-alpha isoform X1.	Inositol polyphosphate 5-phosphatase OCRL-1 isoform X1.	0.629
APPL1	RAB20	A0A3Q0HAC2	A0A1U7RC51	DCC-interacting protein 13-alpha isoform X1.	Ras-related protein Rab-20.	0.860
APPL1	RAB22A	A0A3Q0HAC2	A0A1U7RUF6	DCC-interacting protein 13-alpha isoform X1.	Ras-related protein Rab-22A.	0.860
APPL1	RAB31	A0A3Q0HAC2	A0A3Q0HIG2	DCC-interacting protein 13-alpha isoform X1.	Ras-related protein Rab-31.	0.860
APPL2	APPL1	A0A1U7S4N5	A0A3Q0HAC2	DCC-interacting protein 13-beta isoform X1.	DCC-interacting protein 13-alpha isoform X1.	0.992
APPL2	LOC112548464	A0A1U7S4N5	A0A3Q0FS01	DCC-interacting protein 13-beta isoform X1.	Uncharacterized protein LOC112548464 isoform X1.	0.661
APPL2	LOC112549188	A0A1U7S4N5	A0A3Q0G133	DCC-interacting protein 13-beta isoform X1.	Uncharacterized protein LOC112549188 isoform X1.	0.546
APPL2	RAB20	A0A1U7S4N5	A0A1U7RC51	DCC-interacting protein 13-beta isoform X1.	Ras-related protein Rab-20.	0.860
APPL2	RAB22A	A0A1U7S4N5	A0A1U7RUF6	DCC-interacting protein 13-beta isoform X1.	Ras-related protein Rab-22A.	0.860
APPL2	RAB31	A0A1U7S4N5	A0A3Q0HIG2	DCC-interacting protein 13-beta isoform X1.	Ras-related protein Rab-31.	0.860
INPP5B	APPL1	A0A3Q0HFQ8	A0A3Q0HAC2	Type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X3.	DCC-interacting protein 13-alpha isoform X1.	0.555
INPP5B	OCRL	A0A3Q0HFQ8	A0A3Q0H2B5	Type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X3.	Inositol polyphosphate 5-phosphatase OCRL-1 isoform X1.	0.951
INPP5B	PIP4P1	A0A3Q0HFQ8	A0A3Q0FRJ0	Type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X3.	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).	0.900
LOC102368346	LOC102371494	A0A1U7RFQ8	A0A1U7SC90	Toll-like receptor 2 type-2; Belongs to the Toll-like receptor family.	Toll-like receptor 1.	0.904
LOC102368346	LOC102373745	A0A1U7RFQ8	A0A1U7RU44	Toll-like receptor 2 type-2; Belongs to the Toll-like receptor family.	Toll-like receptor 1; Belongs to the Toll-like receptor family.	0.904
LOC102371494	LOC102368346	A0A1U7SC90	A0A1U7RFQ8	Toll-like receptor 1.	Toll-like receptor 2 type-2; Belongs to the Toll-like receptor family.	0.904