(12 nodes) Insulin-like growth factor-binding protein, IGFBP network (Alligator sinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	WISP1	WNT1-inducible-signaling pathway protein 1 isoform X1. (359 aa)
	HTRA3	Serine protease HTRA3 isoform X1. (466 aa)
	KAZALD1	Kazal-type serine protease inhibitor domain-containing protein 1. (295 aa)
	LOC102375332	Kazal-type serine protease inhibitor domain-containing protein 1-like. (296 aa)
	ESM1	Endothelial cell-specific molecule 1. (185 aa)
	IGFBP1	Insulin-like growth factor-binding protein 1. (294 aa)
	LOC102371210	Connective tissue growth factor-like. (350 aa)
	IGFBP5	Insulin-like growth factor-binding protein 5. (238 aa)
	IGFBP4	Insulin-like growth factor-binding protein 4. (256 aa)
	CYR61	Protein CYR61. (374 aa)
	WISP2	WNT1-inducible-signaling pathway protein 2 isoform X1. (251 aa)
	WISP3	WNT1-inducible-signaling pathway protein 3. (354 aa)