STRINGSTRING
FGF9 FGF9 FGF10 FGF10 FGF6 FGF6 FGF1 FGF1 FGF5 FGF5 FGF23 FGF23 FGF16 FGF16 FGF8 FGF8 FGF14 FGF14 LOC102386460 LOC102386460 FGF20 FGF20 LOC102377132 LOC102377132 LOC102383676 LOC102383676 FGF21 FGF21 FGF22 FGF22 LOC102369595 LOC102369595 LOC112547978 LOC112547978 FGF11 FGF11 FGF17 FGF17 RP1 RP1 FGF18 FGF18 IL18 IL18 FGF13 FGF13 FGF12 FGF12 FGF4 FGF4 FGF3 FGF3 FGF2 FGF2 FGF19 FGF19
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (221 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (163 aa)
FGF23Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
LOC102386460Interleukin-1. (263 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (173 aa)
LOC102377132Interleukin-1 family member 10. (181 aa)
LOC102383676DTW domain-containing protein 1 isoform X1; Belongs to the heparin-binding growth factors family. (490 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (147 aa)
LOC102369595Interleukin-1; Belongs to the IL-1 family. (279 aa)
LOC112547978Interleukin-1. (241 aa)
FGF11Fibroblast growth factor 11; Belongs to the heparin-binding growth factors family. (266 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
RP1Oxygen-regulated protein 1. (2831 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (239 aa)
IL18Interleukin-18 isoform X1. (231 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (263 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (164 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (196 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (236 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (134 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa)
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
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