(39 nodes) Six-bladed beta-propeller, TolB-like network (Alligator sinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NID1	Nidogen-1. (1221 aa)
	NID2	Nidogen-2. (1246 aa)
	LOC102383173	Regucalcin-like. (299 aa)
	LRP1	LOW QUALITY PROTEIN: prolow-density lipoprotein receptor-related protein 1. (4714 aa)
	NHLRC4	NHL-repeat-containing protein 4. (373 aa)
	LOC102378099	Hedgehog-interacting protein-like isoform X1. (185 aa)
	LOC102384636	Prolow-density lipoprotein receptor-related protein 1-like. (2164 aa)
	LOC102379160	LOW QUALITY PROTEIN: tripartite motif-containing protein 2-like. (553 aa)
	HHIPL1	HHIP-like protein 1. (766 aa)
	LRP5	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1593 aa)
	SORL1	Sortilin-related receptor isoform X1. (2109 aa)
	TENM4	LOW QUALITY PROTEIN: teneurin-4. (2821 aa)
	LOC112550140	Uncharacterized protein LOC112550140. (320 aa)
	TENM1	Teneurin-1. (2713 aa)
	LOC102385477	Teneurin-2. (2693 aa)
	EGF	Pro-epidermal growth factor. (1257 aa)
	LRP2	Low-density lipoprotein receptor-related protein 2 isoform X1. (4653 aa)
	NHLRC1	E3 ubiquitin-protein ligase NHLRC1. (400 aa)
	PAM	Peptidyl-glycine alpha-amidating monooxygenase isoform X1. (979 aa)
	TENM3	Teneurin-3 isoform X1. (2877 aa)
	LRP4	Low-density lipoprotein receptor-related protein 4. (1885 aa)
	LRP8	Low-density lipoprotein receptor-related protein 8. (1181 aa)
	APMAP	Adipocyte plasma membrane-associated protein isoform X1. (387 aa)
	VLDLR	Very low-density lipoprotein receptor. (861 aa)
	NHLRC3	NHL repeat-containing protein 3. (347 aa)
	TRIM56	E3 ubiquitin-protein ligase TRIM56. (679 aa)
	LRP1B	Low-density lipoprotein receptor-related protein 1B. (4577 aa)
	LOC102370400	Serum paraoxonase/arylesterase 2 isoform X1. (341 aa)
	LOC102379291	HHIP-like protein 2 isoform X1. (1125 aa)
	TRIM32	E3 ubiquitin-protein ligase TRIM32. (647 aa)
	ROS1	Tyrosine-protein kinase receptor. (2310 aa)
	LOC102382783	Regucalcin. (299 aa)
	LDLR	Low-density lipoprotein receptor isoform X1. (920 aa)
	TRIM2	Tripartite motif-containing protein 2. (744 aa)
	LRP6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1604 aa)
	TRIM71	E3 ubiquitin-protein ligase TRIM71. (566 aa)
	NHLRC2	NHL repeat-containing protein 2 isoform X1. (722 aa)
	LOC102386815	Hedgehog-interacting protein-like. (454 aa)
	APEH	Acylamino-acid-releasing enzyme. (707 aa)

Your Current Organism:

Alligator sinensis

NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EGF	LOC102384636	A0A3Q0GQU8	A0A3Q0FNH1	Pro-epidermal growth factor.	Prolow-density lipoprotein receptor-related protein 1-like.	0.424
EGF	LRP2	A0A3Q0GQU8	A0A3Q0GR39	Pro-epidermal growth factor.	Low-density lipoprotein receptor-related protein 2 isoform X1.	0.424
EGF	LRP4	A0A3Q0GQU8	A0A3Q0GV95	Pro-epidermal growth factor.	Low-density lipoprotein receptor-related protein 4.	0.424
LOC102378099	LOC102386815	A0A3Q0FMJ2	A0A1U7SVX6	Hedgehog-interacting protein-like isoform X1.	Hedgehog-interacting protein-like.	0.900
LOC102378099	SORL1	A0A3Q0FMJ2	A0A3Q0GCD1	Hedgehog-interacting protein-like isoform X1.	Sortilin-related receptor isoform X1.	0.654
LOC102382783	LOC102383173	A0A1U7RQF5	A0A1U8DNL4	Regucalcin.	Regucalcin-like.	0.901
LOC102383173	LOC102382783	A0A1U8DNL4	A0A1U7RQF5	Regucalcin-like.	Regucalcin.	0.901
LOC102384636	EGF	A0A3Q0FNH1	A0A3Q0GQU8	Prolow-density lipoprotein receptor-related protein 1-like.	Pro-epidermal growth factor.	0.424
LOC102386815	LOC102378099	A0A1U7SVX6	A0A3Q0FMJ2	Hedgehog-interacting protein-like.	Hedgehog-interacting protein-like isoform X1.	0.900
LOC102386815	SORL1	A0A1U7SVX6	A0A3Q0GCD1	Hedgehog-interacting protein-like.	Sortilin-related receptor isoform X1.	0.654
LRP2	EGF	A0A3Q0GR39	A0A3Q0GQU8	Low-density lipoprotein receptor-related protein 2 isoform X1.	Pro-epidermal growth factor.	0.424
LRP4	EGF	A0A3Q0GV95	A0A3Q0GQU8	Low-density lipoprotein receptor-related protein 4.	Pro-epidermal growth factor.	0.424
LRP5	LRP6	A0A3Q0G4J6	A0A1U7S9W6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.981
LRP6	LRP5	A0A1U7S9W6	A0A3Q0G4J6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.981
SORL1	LOC102378099	A0A3Q0GCD1	A0A3Q0FMJ2	Sortilin-related receptor isoform X1.	Hedgehog-interacting protein-like isoform X1.	0.654
SORL1	LOC102386815	A0A3Q0GCD1	A0A1U7SVX6	Sortilin-related receptor isoform X1.	Hedgehog-interacting protein-like.	0.654
TRIM32	TRIM56	A0A1U7RYU9	A0A1U7R1S8	E3 ubiquitin-protein ligase TRIM32.	E3 ubiquitin-protein ligase TRIM56.	0.635
TRIM56	TRIM32	A0A1U7R1S8	A0A1U7RYU9	E3 ubiquitin-protein ligase TRIM56.	E3 ubiquitin-protein ligase TRIM32.	0.635