(19 nodes) Zinc finger, RanBP2-type superfamily network (Alligator sinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102376251	TATA-binding protein-associated factor 2N isoform X1. (484 aa)
	ZRANB2	Zinc finger Ran-binding domain-containing protein 2; May interfere with constitutive 5'-splice site selection. Belongs to the ZRANB2 family. (343 aa)
	NUP153	Nuclear pore complex protein Nup153. (1447 aa)
	MDM4	Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (474 aa)
	NEIL3	Endonuclease 8-like 3. (576 aa)
	CAPN15	Calpain-15; Belongs to the peptidase C2 family. (1089 aa)
	FUS	RNA-binding protein FUS. (517 aa)
	RBM10	RNA-binding protein 10 isoform X1. (948 aa)
	RNF31	E3 ubiquitin-protein ligase RNF31. (930 aa)
	EWSR1	RNA-binding protein EWS isoform X1. (660 aa)
	TAB2	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (557 aa)
	LOC106721793	E3 SUMO-protein ligase RanBP2 isoform X1. (3314 aa)
	SHARPIN	LOW QUALITY PROTEIN: sharpin. (588 aa)
	TAB3	TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X1. (698 aa)
	RBM5	RNA-binding protein 5 isoform X1. (890 aa)
	MDM2	E3 ubiquitin-protein ligase Mdm2 isoform X3. (591 aa)
	ZRANB3	DNA annealing helicase and endonuclease ZRANB3 isoform X1. (1117 aa)
	ZRANB1	LOW QUALITY PROTEIN: ubiquitin thioesterase ZRANB1. (714 aa)
	NPLOC4	Nuclear protein localization protein 4 homolog isoform X1. (609 aa)

Your Current Organism:

Alligator sinensis

NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EWSR1	FUS	A0A3Q0FTB0	A0A1U8DYJ9	RNA-binding protein EWS isoform X1.	RNA-binding protein FUS.	0.474
EWSR1	LOC102376251	A0A3Q0FTB0	A0A1U7SGL0	RNA-binding protein EWS isoform X1.	TATA-binding protein-associated factor 2N isoform X1.	0.474
EWSR1	RBM10	A0A3Q0FTB0	A0A3Q0FM10	RNA-binding protein EWS isoform X1.	RNA-binding protein 10 isoform X1.	0.405
EWSR1	RBM5	A0A3Q0FTB0	A0A3Q0GTN8	RNA-binding protein EWS isoform X1.	RNA-binding protein 5 isoform X1.	0.405
FUS	EWSR1	A0A1U8DYJ9	A0A3Q0FTB0	RNA-binding protein FUS.	RNA-binding protein EWS isoform X1.	0.474
LOC102376251	EWSR1	A0A1U7SGL0	A0A3Q0FTB0	TATA-binding protein-associated factor 2N isoform X1.	RNA-binding protein EWS isoform X1.	0.474
LOC106721793	MDM2	A0A3Q0HCJ3	A0A3Q0H065	E3 SUMO-protein ligase RanBP2 isoform X1.	E3 ubiquitin-protein ligase Mdm2 isoform X3.	0.435
LOC106721793	MDM4	A0A3Q0HCJ3	A0A1U8DDY2	E3 SUMO-protein ligase RanBP2 isoform X1.	Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family.	0.411
LOC106721793	NUP153	A0A3Q0HCJ3	A0A1U8DG74	E3 SUMO-protein ligase RanBP2 isoform X1.	Nuclear pore complex protein Nup153.	0.994
MDM2	LOC106721793	A0A3Q0H065	A0A3Q0HCJ3	E3 ubiquitin-protein ligase Mdm2 isoform X3.	E3 SUMO-protein ligase RanBP2 isoform X1.	0.435
MDM2	MDM4	A0A3Q0H065	A0A1U8DDY2	E3 ubiquitin-protein ligase Mdm2 isoform X3.	Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family.	0.999
MDM4	LOC106721793	A0A1U8DDY2	A0A3Q0HCJ3	Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family.	E3 SUMO-protein ligase RanBP2 isoform X1.	0.411
MDM4	MDM2	A0A1U8DDY2	A0A3Q0H065	Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family.	E3 ubiquitin-protein ligase Mdm2 isoform X3.	0.999
NPLOC4	ZRANB1	A0A1U7S524	A0A1U7RZI9	Nuclear protein localization protein 4 homolog isoform X1.	LOW QUALITY PROTEIN: ubiquitin thioesterase ZRANB1.	0.498
NUP153	LOC106721793	A0A1U8DG74	A0A3Q0HCJ3	Nuclear pore complex protein Nup153.	E3 SUMO-protein ligase RanBP2 isoform X1.	0.994
RBM10	EWSR1	A0A3Q0FM10	A0A3Q0FTB0	RNA-binding protein 10 isoform X1.	RNA-binding protein EWS isoform X1.	0.405
RBM5	EWSR1	A0A3Q0GTN8	A0A3Q0FTB0	RNA-binding protein 5 isoform X1.	RNA-binding protein EWS isoform X1.	0.405
RNF31	SHARPIN	A0A3Q0FSD0	A0A3Q0HHL5	E3 ubiquitin-protein ligase RNF31.	LOW QUALITY PROTEIN: sharpin.	0.993
RNF31	TAB2	A0A3Q0FSD0	A0A3Q0FUB8	E3 ubiquitin-protein ligase RNF31.	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2.	0.439
RNF31	TAB3	A0A3Q0FSD0	A0A3Q0G8M5	E3 ubiquitin-protein ligase RNF31.	TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X1.	0.546