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| | KPNA3 | Importin subunit alpha; Belongs to the importin alpha family. (497 aa) |
| | VPS29 | Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (202 aa) |
| | SEC13 | Protein SEC13 homolog; Belongs to the WD repeat SEC13 family. (300 aa) |
| | NUP107 | Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (930 aa) |
| | LOC102381047 | AP-2 complex subunit beta. (424 aa) |
| | LOC102380799 | Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family. (116 aa) |
| | COPA | Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1244 aa) |
| | ARCN1 | Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (527 aa) |
| | AP1M1 | AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (397 aa) |
| | LOC102371683 | Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (1061 aa) |
| | COPZ2 | Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (187 aa) |
| | NUP35 | Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (320 aa) |
| | AP4M1 | LOW QUALITY PROTEIN: AP-4 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (464 aa) |
| | LOC102377904 | Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (195 aa) |
| | LOC102374573 | AP-3 complex subunit beta-1. (884 aa) |
| | ATG9A | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (753 aa) |
| | VPS37B | Vacuolar protein sorting-associated protein 37B. (267 aa) |
| | AP1S3 | AP-1 complex subunit sigma-3. (257 aa) |
| | SEC23A | Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (765 aa) |
| | LOC102383202 | AP-3 complex subunit beta-1-like isoform X1. (362 aa) |
| | TOM1L2 | TOM1-like protein 2 isoform X1; Belongs to the TOM1 family. (496 aa) |
| | SEH1L | Nucleoporin SEH1; Belongs to the WD repeat SEC13 family. (408 aa) |
| | KPNA4 | Importin subunit alpha; Belongs to the importin alpha family. (560 aa) |
| | VPS37A | Vacuolar protein sorting-associated protein 37A isoform X1. (333 aa) |
| | TIMM44 | Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (422 aa) |
| | VPS37C | Vacuolar protein sorting-associated protein 37C. (116 aa) |
| | VPS37D | Vacuolar protein sorting-associated protein 37D isoform X1. (305 aa) |
| | COPG2 | Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (907 aa) |
| | AP3M1 | LOW QUALITY PROTEIN: AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (427 aa) |
| | ATG4A | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (468 aa) |
| | TIMM50 | Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (280 aa) |
| | TRAM2 | Translocating chain-associated membrane protein; Belongs to the TRAM family. (365 aa) |
| | ATG7 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (815 aa) |
| | ATG4B | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (442 aa) |
| | COPZ1 | Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (264 aa) |
| | SAR1B | GTP-binding protein SAR1b; Belongs to the small GTPase superfamily. SAR1 family. (198 aa) |
| | VPS11 | Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (877 aa) |
| | KPNA5 | Importin subunit alpha; Belongs to the importin alpha family. (539 aa) |
| | TIMM9 | Mitochondrial import inner membrane translocase subunit Tim9. (89 aa) |
| | AP3M2 | LOW QUALITY PROTEIN: AP-3 complex subunit mu-2; Belongs to the adaptor complexes medium subunit family. (393 aa) |
| | SEC24C | Protein transport protein Sec24C isoform X1. (1186 aa) |
| | SEC61A1 | Protein transport protein Sec61 subunit alpha. (476 aa) |
| | SEC16A | Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (2471 aa) |
| | AP3S1 | AP-3 complex subunit sigma-1 isoform X1. (193 aa) |
| | GOSR2 | Golgi SNAP receptor complex member 2 isoform X1; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. (212 aa) |
| | COPG1 | Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (874 aa) |
| | TOM1 | Target of Myb protein 1 isoform X1; Belongs to the TOM1 family. (483 aa) |
| | LIN7C | Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (197 aa) |
| | COG6 | Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. (650 aa) |
| | TOM1L1 | TOM1-like protein 1; Belongs to the TOM1 family. (457 aa) |
| | NUP85 | Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (650 aa) |
| | SEC24D | Protein transport protein Sec24D. (1038 aa) |
| | NMD3 | 60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (503 aa) |
| | VPS41 | Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (854 aa) |
| | TIMM8A | Mitochondrial import inner membrane translocase subunit Tim8 A; Belongs to the small Tim family. (94 aa) |
| | SEC24A | Protein transport protein Sec24A isoform X1. (1101 aa) |
| | SEC61B | Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (96 aa) |
| | BBS7 | Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (720 aa) |
| | EXOC2 | Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (925 aa) |
| | AP4S1 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (144 aa) |
| | AP1B1 | AP complex subunit beta. (958 aa) |
| | RAN | GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (216 aa) |
| | SEC61A2 | LOW QUALITY PROTEIN: protein transport protein Sec61 subunit alpha. (474 aa) |
| | ATG4D | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (446 aa) |
| | AP1S2 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (157 aa) |
| | SFT2D2 | Vesicle transport protein; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. (160 aa) |
| | SAR1A | GTP-binding protein SAR1a; Belongs to the small GTPase superfamily. SAR1 family. (198 aa) |
| | SNF8 | Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa) |
| | AP1M2 | AP-1 complex subunit mu-2 isoform X1; Belongs to the adaptor complexes medium subunit family. (499 aa) |
| | SNX5 | Sorting nexin; Involved in several stages of intracellular trafficking. (402 aa) |
| | VPS35 | Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (804 aa) |
| | KPNA7 | Importin subunit alpha; Belongs to the importin alpha family. (518 aa) |
| | SEC24B | Protein transport protein Sec24B. (1193 aa) |
| | LOC102369829 | ER lumen protein-retaining receptor. (263 aa) |
| | AP3D1 | AP-3 complex subunit delta-1 isoform X1. (1213 aa) |
| | LOC102375336 | AP-2 complex subunit beta-like. (428 aa) |
| | LOC102381531 | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (957 aa) |
| | AP1G1 | AP-1 complex subunit gamma. (823 aa) |
| | LOC102386811 | Vesicle transport protein; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. (95 aa) |
| | AP3B2 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1153 aa) |
| | AP4E1 | AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family. (1085 aa) |
| | AP2M1 | AP-2 complex subunit mu isoform X1; Belongs to the adaptor complexes medium subunit family. (437 aa) |
| | AP2A1 | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (969 aa) |
| | SERP2 | Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family. (65 aa) |
| | AP5M1 | AP-5 complex subunit mu-1 isoform X1; Belongs to the adaptor complexes medium subunit family. (428 aa) |
| | KDELR1 | ER lumen protein-retaining receptor. (217 aa) |
| | SDAD1 | Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (687 aa) |
| | KPNA2 | Importin subunit alpha; Belongs to the importin alpha family. (515 aa) |
| | KPNA6 | Importin subunit alpha; Belongs to the importin alpha family. (564 aa) |
| | COPB1 | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (953 aa) |
| | EXOC7 | Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (723 aa) |
| | ATG3 | Autophagy-related protein 3. (314 aa) |
| | VPS16 | Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (813 aa) |
| | AP2S1 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa) |
| | NUP93 | Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (819 aa) |
| | VPS28 | Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (219 aa) |
| | SEC23B | Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (770 aa) |
| | TIMM10 | Mitochondrial import inner membrane translocase subunit Tim10. (90 aa) |
| | AP1S1 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (187 aa) |
| | ATG4C | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (459 aa) |
| | TIMM8B | Mitochondrial import inner membrane translocase subunit Tim8 B; Belongs to the small Tim family. (85 aa) |
| | LOC102369408 | Arpin-like. (311 aa) |
| | KDELR3 | ER lumen protein-retaining receptor. (214 aa) |
| | ENY2 | Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...] (96 aa) |
| | KPNA1 | Importin subunit alpha; Belongs to the importin alpha family. (538 aa) |
| | AP4B1 | AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (600 aa) |
