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PLCB2 PLCB2 IMPA1 IMPA1 PLCZ1 PLCZ1 PLCD3 PLCD3 ITPKA ITPKA PLCG2 PLCG2 PLCD1 PLCD1 IP6K3 IP6K3 ISYNA1 ISYNA1 NUDT4 NUDT4 SASH3 SASH3 PLCL1 PLCL1 MIOX MIOX IP6K2 IP6K2 PLCL2 PLCL2 INPP1 INPP1 IMPA2 IMPA2 ITPK1 ITPK1 LOC102368100 LOC102368100 SASH1 SASH1 IP6K1 IP6K1 LOC102378130 LOC102378130 PLCB4 PLCB4 FAM208A FAM208A LOC102368895 LOC102368895 INPP4A INPP4A INPP5D INPP5D PLCG1 PLCG1 PLCE1 PLCE1 MINPP1 MINPP1 PLCB3 PLCB3 INPPL1 INPPL1 LOC112548809 LOC112548809 LOC102375443 LOC102375443 PLCB1 PLCB1 PPIP5K2 PPIP5K2 IPPK IPPK INPP5A INPP5A OCRL OCRL PPIP5K1 PPIP5K1 INPP4B INPP4B PLCH2 PLCH2 SYNJ1 SYNJ1 INPP5B INPP5B IPMK IPMK ITPKB ITPKB PLCH1 PLCH1 INPP5J INPP5J
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1207 aa)
IMPA1Inositol-1-monophosphatase. (278 aa)
PLCZ1Phosphoinositide phospholipase C. (634 aa)
PLCD3Phosphoinositide phospholipase C. (754 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (333 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
PLCD1Phosphoinositide phospholipase C. (771 aa)
IP6K3Kinase; Belongs to the inositol phosphokinase (IPK) family. (415 aa)
ISYNA1Inositol-3-phosphate synthase 1. (432 aa)
NUDT4Diphosphoinositol polyphosphate phosphohydrolase 2. (180 aa)
SASH3SAM and SH3 domain-containing protein 3 isoform X1. (382 aa)
PLCL1Phosphoinositide phospholipase C. (997 aa)
MIOXInositol oxygenase. (286 aa)
IP6K2Kinase; Belongs to the inositol phosphokinase (IPK) family. (424 aa)
PLCL2Phosphoinositide phospholipase C. (996 aa)
INPP1Inositol polyphosphate 1-phosphatase. (376 aa)
IMPA2Inositol-1-monophosphatase. (274 aa)
ITPK1Inositol-tetrakisphosphate 1-kinase. (407 aa)
LOC102368100Type I inositol 1,4,5-trisphosphate 5-phosphatase-like. (157 aa)
SASH1SAM and SH3 domain-containing protein 1 isoform X1. (1155 aa)
IP6K1Kinase; Belongs to the inositol phosphokinase (IPK) family. (434 aa)
LOC102378130Uncharacterized protein LOC102378130 isoform X2. (704 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
FAM208AProtein TASOR. (1541 aa)
LOC1023688951-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1295 aa)
INPP4AType I inositol 3,4-bisphosphate 4-phosphatase isoform X1. (976 aa)
INPP5DPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1. (1209 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1282 aa)
PLCE11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1. (2319 aa)
MINPP1Multiple inositol polyphosphate phosphatase 1; Belongs to the histidine acid phosphatase family. (211 aa)
PLCB3Phosphoinositide phospholipase C. (795 aa)
INPPL1Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2. (1267 aa)
LOC112548809Inositol-tetrakisphosphate 1-kinase-like. (195 aa)
LOC102375443Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2-like isoform X1. (1114 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa)
PPIP5K2Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1327 aa)
IPPKInositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (498 aa)
INPP5AType I inositol 1,4,5-trisphosphate 5-phosphatase. (145 aa)
OCRLInositol polyphosphate 5-phosphatase OCRL-1 isoform X1. (836 aa)
PPIP5K1Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1355 aa)
INPP4BType II inositol 3,4-bisphosphate 4-phosphatase. (1055 aa)
PLCH2Phosphoinositide phospholipase C. (1601 aa)
SYNJ1Synaptojanin-1. (1589 aa)
INPP5BType II inositol 1,4,5-trisphosphate 5-phosphatase isoform X3. (921 aa)
IPMKKinase; Belongs to the inositol phosphokinase (IPK) family. (366 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (396 aa)
PLCH1Phosphoinositide phospholipase C. (1667 aa)
INPP5JPhosphatidylinositol 4,5-bisphosphate 5-phosphatase A isoform X1. (1054 aa)
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
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