STRINGSTRING
FADD FADD MAPK8 MAPK8 IRF3 IRF3 VWC2L VWC2L TRAF6 TRAF6 DUSP3 DUSP3 RPS27A RPS27A LOC102381636 LOC102381636 LRRC31 LRRC31 NFKBIA NFKBIA FOS FOS UBC UBC TANK TANK LOC102373025 LOC102373025 NKIRAS1 NKIRAS1 BIRC7 BIRC7 TRAF3 TRAF3 VWC2 VWC2 PPP4R4 PPP4R4 MAPKAPK2 MAPKAPK2 UBE2N UBE2N MAPK14 MAPK14 TRAF5 TRAF5 DUSP7 DUSP7 LOC102386674 LOC102386674 IKBKB IKBKB MAPKAPK3 MAPKAPK3 MAP2K3 MAP2K3 LOC102378458 LOC102378458 IRAK2 IRAK2 PPP2R1A PPP2R1A IKBKG IKBKG N4BP1 N4BP1 LOC102371602 LOC102371602 APP APP NLRX1 NLRX1 UBE2D1 UBE2D1 SARM1 SARM1 LOC102383734 LOC102383734 KHNYN KHNYN KXD1 KXD1 CREB1 CREB1 MAP3K20 MAP3K20 NOD1 NOD1 NKIRAS2 NKIRAS2 NFKBIB NFKBIB DUSP6 DUSP6 LRRC14 LRRC14 LOC102378924 LOC102378924 RIPK2 RIPK2 LRRC74A LRRC74A MAPK1 MAPK1 CHUK CHUK LRRC34 LRRC34 IKBKE IKBKE JUN JUN LOC102374298 LOC102374298 USP18 USP18 ATF2 ATF2 LY96 LY96 UBA52 UBA52 RIPK1 RIPK1 LOC106722550 LOC106722550 NFKB2 NFKB2 PPP2CB PPP2CB ELK1 ELK1 ATF1 ATF1 LOC102382702 LOC102382702 LOC102378436 LOC102378436 LOC106723425 LOC106723425 FOSL2 FOSL2 LOC102383516 LOC102383516 LOC102374462 LOC102374462 TBK1 TBK1 RPS6KA5 RPS6KA5 FNBP4 FNBP4 MAP2K7 MAP2K7 LOC102371867 LOC102371867 LOC102375250 LOC102375250 RIPK3 RIPK3 LOC102372525 LOC102372525 LRRC45 LRRC45 LOC102379011 LOC102379011 LOC112548578 LOC112548578 TONSL TONSL LOC102383014 LOC102383014 TAB2 TAB2 MAPK7 MAPK7 LOC112548426 LOC112548426 LOC102380544 LOC102380544 MAP2K4 MAP2K4 LOC106723326 LOC106723326 MAP2K6 MAP2K6 LOC102372275 LOC102372275 LOC102384011 LOC102384011 LOC102374542 LOC102374542 LOC106721866 LOC106721866 PPP2CA PPP2CA LOC102386995 LOC102386995 LOC102372372 LOC102372372 MAP3K7 MAP3K7 PTPN11 PTPN11 TAB3 TAB3 LOC102382137 LOC102382137 S100B S100B VRK3 VRK3 NAIP NAIP UBE2D2 UBE2D2 TLR4 TLR4 MAPK9 MAPK9 USP14 USP14 TAB1 TAB1 RELCH RELCH ATF7 ATF7 LOC102383643 LOC102383643 IRAK1 IRAK1 NLRC5 NLRC5 LRRC71 LRRC71 LOC102368067 LOC102368067 LOC112551609 LOC112551609 LOC102387626 LOC102387626 LOC112551885 LOC112551885 MAPK11 MAPK11 LOC102388542 LOC102388542 UBB UBB LOC102372690 LOC102372690 RPS6KA2 RPS6KA2 NFKB1 NFKB1 PPP4R1 PPP4R1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FADDFAS-associated death domain protein. (191 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
IRF3Interferon regulatory factor 3 isoform X2. (432 aa)
VWC2LVon Willebrand factor C domain-containing protein 2-like. (229 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (183 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
LOC102381636Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (127 aa)
LRRC31Leucine-rich repeat-containing protein 31 isoform X1. (611 aa)
NFKBIANF-kappa-B inhibitor alpha. (316 aa)
FOSProto-oncogene c-Fos. (335 aa)
UBCpolyubiquitin-C. (381 aa)
TANKTRAF family member-associated NF-kappa-B activator isoform X1. (485 aa)
LOC102373025Uncharacterized protein LOC102373025. (1078 aa)
NKIRAS1NF-kappa-B inhibitor-interacting Ras-like protein 1. (166 aa)
BIRC7Baculoviral IAP repeat-containing protein 7 isoform X1. (422 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)
VWC2Brorin isoform X1. (331 aa)
PPP4R4Serine/threonine-protein phosphatase 4 regulatory subunit 4 isoform X1. (864 aa)
MAPKAPK2MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (375 aa)
UBE2NUbiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (382 aa)
LOC102386674Cyclic AMP-responsive element-binding protein 5-like isoform X1. (186 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (757 aa)
MAPKAPK3MAP kinase-activated protein kinase 3 isoform X1; Belongs to the protein kinase superfamily. (387 aa)
MAP2K3Dual specificity mitogen-activated protein kinase kinase 3 isoform X1; Belongs to the protein kinase superfamily. (337 aa)
LOC102378458Serine/threonine-protein phosphatase 4 regulatory subunit 1-like isoform X1. (964 aa)
IRAK2Interleukin-1 receptor-associated kinase-like 2. (732 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (589 aa)
IKBKGNF-kappa-B essential modulator. (534 aa)
N4BP1NEDD4-binding protein 1. (865 aa)
LOC102371602Protein S100; Belongs to the S-100 family. (100 aa)
APPAmyloid-beta A4 protein isoform X1. (716 aa)
NLRX1NLR family member X1. (980 aa)
UBE2D1Ubiquitin-conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (124 aa)
SARM1Sterile alpha and TIR motif-containing protein 1. (718 aa)
LOC102383734Toll-like receptor 2. (439 aa)
KHNYNProtein KHNYN. (891 aa)
KXD1kxDL motif-containing protein 1. (176 aa)
CREB1Cyclic AMP-responsive element-binding protein 1. (327 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20 isoform X3. (807 aa)
NOD1Nucleotide-binding oligomerization domain-containing protein 1 isoform X1. (951 aa)
NKIRAS2NF-kappa-B inhibitor-interacting Ras-like protein 2. (191 aa)
NFKBIBNF-kappa-B inhibitor beta. (179 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (346 aa)
LRRC14Leucine-rich repeat-containing protein 14 isoform X1. (511 aa)
LOC102378924Mitogen-activated protein kinase. (557 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2. (510 aa)
LRRC74ALeucine-rich repeat-containing protein 74A. (478 aa)
MAPK1Mitogen-activated protein kinase. (422 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha. (735 aa)
LRRC34Leucine-rich repeat-containing protein 34. (417 aa)
IKBKEInhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1. (752 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (282 aa)
LOC102374298Receptor-interacting serine/threonine-protein kinase 2-like. (565 aa)
USP18Ubl carboxyl-terminal hydrolase 18; Belongs to the peptidase C19 family. (380 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (487 aa)
LY96Lymphocyte antigen 96 isoform X1. (192 aa)
UBA52ubiquitin-60S ribosomal protein L40. (104 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1 isoform X1. (711 aa)
LOC106722550LOW QUALITY PROTEIN: mitogen-activated protein kinase 15-like. (312 aa)
NFKB2Nuclear factor NF-kappa-B p100 subunit. (903 aa)
PPP2CBSerine/threonine-protein phosphatase. (244 aa)
ELK1ETS domain-containing protein Elk-1 isoform X1. (396 aa)
ATF1Cyclic AMP-dependent transcription factor ATF-1 isoform X1. (318 aa)
LOC102382702NACHT, LRR and PYD domains-containing protein 3-like. (393 aa)
LOC102378436Uncharacterized protein LOC102378436. (734 aa)
LOC106723425NACHT, LRR and PYD domains-containing protein 12-like. (382 aa)
FOSL2Fos-related antigen 2 isoform X1. (351 aa)
LOC102383516LOW QUALITY PROTEIN: NACHT, LRR and PYD domains-containing protein 3-like. (473 aa)
LOC102374462NACHT, LRR and PYD domains-containing protein 12-like. (233 aa)
TBK1Serine/threonine-protein kinase TBK1 isoform X1. (741 aa)
RPS6KA5Ribosomal protein S6 kinase. (808 aa)
FNBP4Formin-binding protein 4. (978 aa)
MAP2K7Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (349 aa)
LOC102371867Non-specific serine/threonine protein kinase. (1284 aa)
LOC102375250Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (564 aa)
RIPK3Receptor-interacting serine/threonine-protein kinase 3 isoform X1. (509 aa)
LOC102372525NACHT, LRR and PYD domains-containing protein 12-like. (890 aa)
LRRC45Leucine-rich repeat-containing protein 45. (478 aa)
LOC102379011NACHT, LRR and PYD domains-containing protein 12-like. (357 aa)
LOC112548578NACHT, LRR and PYD domains-containing protein 12-like. (113 aa)
TONSLTonsoku-like protein isoform X1. (1296 aa)
LOC102383014LOW QUALITY PROTEIN: NACHT, LRR and PYD domains-containing protein 3-like. (1049 aa)
TAB2TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (557 aa)
MAPK7Mitogen-activated protein kinase. (885 aa)
LOC112548426NACHT, LRR and PYD domains-containing protein 12-like. (179 aa)
LOC102380544NACHT, LRR and PYD domains-containing protein 3-like. (555 aa)
MAP2K4Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (422 aa)
LOC106723326Uncharacterized protein LOC106723326 isoform X1. (504 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6 isoform X1; Belongs to the protein kinase superfamily. (435 aa)
LOC102372275LOW QUALITY PROTEIN: NACHT, LRR and PYD domains-containing protein 3-like. (613 aa)
LOC102384011NACHT, LRR and PYD domains-containing protein 3-like. (609 aa)
LOC102374542Mitogen-activated protein kinase. (464 aa)
LOC106721866Ubiquitin-conjugating enzyme E2 variant 1 isoform X1. (119 aa)
PPP2CASerine/threonine-protein phosphatase. (244 aa)
LOC102386995Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (603 aa)
LOC102372372Cyclic AMP-responsive element-binding protein 5 isoform X1. (383 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7 isoform X1. (571 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (609 aa)
TAB3TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X1. (698 aa)
LOC102382137Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (167 aa)
S100BProtein S100-B isoform X1; Belongs to the S-100 family. (108 aa)
VRK3Inactive serine/threonine-protein kinase VRK3. (443 aa)
NAIPBaculoviral IAP repeat-containing protein 1. (448 aa)
UBE2D2Ubiquitin-conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (221 aa)
TLR4LOW QUALITY PROTEIN: toll-like receptor 4; Belongs to the Toll-like receptor family. (849 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
USP14Ubiquitin carboxyl-terminal hydrolase. (555 aa)
TAB1TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X1. (541 aa)
RELCHlisH domain and HEAT repeat-containing protein KIAA1468 homolog isoform X1. (1060 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7 isoform X1. (543 aa)
LOC102383643Uncharacterized protein LOC102383643 isoform X1. (238 aa)
IRAK1Interleukin-1 receptor-associated kinase 1 isoform X2. (543 aa)
NLRC5Protein NLRC5. (1856 aa)
LRRC71Leucine-rich repeat-containing protein 71 isoform X1. (539 aa)
LOC102368067Inhibitor of apoptosis protein-like. (633 aa)
LOC112551609Uncharacterized protein LOC112551609. (264 aa)
LOC102387626NACHT, LRR and PYD domains-containing protein 3-like. (297 aa)
LOC112551885Uncharacterized protein LOC112551885. (311 aa)
MAPK11Mitogen-activated protein kinase. (283 aa)
LOC102388542LOW QUALITY PROTEIN: baculoviral IAP repeat-containing protein 1-like. (1367 aa)
UBBpolyubiquitin-B. (233 aa)
LOC102372690NACHT, LRR and PYD domains-containing protein 3-like isoform X1. (1116 aa)
RPS6KA2Ribosomal protein S6 kinase. (733 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X1. (1022 aa)
PPP4R1LOW QUALITY PROTEIN: serine/threonine-protein phosphatase 4 regulatory subunit 1. (961 aa)
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
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