STRINGSTRING
LOC102381926 LOC102381926 PAK2 PAK2 LOC102384987 LOC102384987 SPNS1 SPNS1 CD3D CD3D RIPK2 RIPK2 CHUK CHUK CD247 CD247 PTPRC PTPRC LOC102374298 LOC102374298 PIK3CB PIK3CB UBA52 UBA52 LOC102368895 LOC102368895 INPP5D INPP5D PAG1 PAG1 PLCG1 PLCG1 CD3E CD3E CD4 CD4 PSMB5 PSMB5 LOC102379235 LOC102379235 PDPK1 PDPK1 LOC102381203 LOC102381203 TAB2 TAB2 LOC102383340 LOC102383340 LAT LAT PIK3CA PIK3CA PSMA1 PSMA1 LOC106721866 LOC106721866 MAP3K7 MAP3K7 LOC102374052 LOC102374052 PSME4 PSME4 PSMD1 PSMD1 LOC102382314 LOC102382314 LOC102378707 LOC102378707 FYB1 FYB1 LOC102376131 LOC102376131 PAK3 PAK3 BCL10 BCL10 UBB UBB PSMD10 PSMD10 PSMA8 PSMA8 MALT1 MALT1 TRAF6 TRAF6 RPS27A RPS27A NFKBIA NFKBIA PAK1 PAK1 UBC UBC FBXW11 FBXW11 SKP1 SKP1 PTPRJ PTPRJ PSMA7 PSMA7 PLCG2 PLCG2 IKBKB IKBKB IKBKG IKBKG LOC102376901 LOC102376901 LOC102379476 LOC102379476 KXD1 KXD1 GRAP2 GRAP2 LCP2 LCP2 PSME2 PSME2 MAP3K20 MAP3K20 LOC102368015 LOC102368015 CARD11 CARD11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102381926H-2 class II histocompatibility antigen, E-S beta chain. (333 aa)
PAK2Non-specific serine/threonine protein kinase. (525 aa)
LOC102384987DLA class II histocompatibility antigen, DR-1 beta chain. (221 aa)
SPNS1LOW QUALITY PROTEIN: protein spinster homolog 1. (475 aa)
CD3DT-cell surface glycoprotein CD3 delta chain. (138 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2. (510 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha. (735 aa)
CD247T-cell surface glycoprotein CD3 zeta chain. (166 aa)
PTPRCReceptor-type tyrosine-protein phosphatase C isoform X1. (1251 aa)
LOC102374298Receptor-interacting serine/threonine-protein kinase 2-like. (565 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
UBA52ubiquitin-60S ribosomal protein L40. (104 aa)
LOC1023688951-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1295 aa)
INPP5DPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1. (1209 aa)
PAG1Phosphoprotein associated with glycosphingolipid-enriched microdomains 1. (427 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1282 aa)
CD3ET-cell surface glycoprotein CD3 epsilon chain. (187 aa)
CD4T-cell surface glycoprotein CD4. (491 aa)
PSMB5Proteasome subunit beta. (249 aa)
LOC102379235Tyrosine-protein kinase. (612 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X2. (701 aa)
LOC102381203LOW QUALITY PROTEIN: uncharacterized protein LOC102381203. (460 aa)
TAB2TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (557 aa)
LOC102383340DLA class II histocompatibility antigen, DR-1 beta chain-like. (188 aa)
LATLinker for activation of T-cells family member 1. (104 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PSMA1Proteasome endopeptidase complex. (265 aa)
LOC106721866Ubiquitin-conjugating enzyme E2 variant 1 isoform X1. (119 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7 isoform X1. (571 aa)
LOC102374052Mucosa-associated lymphoid tissue lymphoma translocation protein 1-like isoform X1. (647 aa)
PSME4Proteasome activator complex subunit 4 isoform X1. (1848 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
LOC102382314Mucosa-associated lymphoid tissue lymphoma translocation protein 1-like. (785 aa)
LOC102378707T-cell receptor-associated transmembrane adapter 1. (183 aa)
FYB1FYN-binding protein 1 isoform X1. (975 aa)
LOC102376131Protein spinster homolog 3 isoform X1. (466 aa)
PAK3Non-specific serine/threonine protein kinase. (550 aa)
BCL10B-cell lymphoma/leukemia 10 isoform X1. (226 aa)
UBBpolyubiquitin-B. (233 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10. (157 aa)
PSMA8Proteasome subunit alpha type. (249 aa)
MALT1Mucosa-associated lymphoid tissue lymphoma translocation protein 1. (770 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
NFKBIANF-kappa-B inhibitor alpha. (316 aa)
PAK1Non-specific serine/threonine protein kinase. (546 aa)
UBCpolyubiquitin-C. (381 aa)
FBXW11F-box/WD repeat-containing protein 11 isoform X1. (531 aa)
SKP1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
PTPRJReceptor-type tyrosine-protein phosphatase eta isoform X1. (1350 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (757 aa)
IKBKGNF-kappa-B essential modulator. (534 aa)
LOC102376901HLA class II histocompatibility antigen, DR alpha chain isoform X1. (257 aa)
LOC102379476Proteasome subunit beta type-9-like. (280 aa)
KXD1kxDL motif-containing protein 1. (176 aa)
GRAP2GRB2-related adapter protein 2. (300 aa)
LCP2Lymphocyte cytosolic protein 2. (539 aa)
PSME2Proteasome activator complex subunit 2. (242 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20 isoform X3. (807 aa)
LOC102368015DLA class II histocompatibility antigen, DR-1 beta chain-like. (188 aa)
CARD11Caspase recruitment domain-containing protein 11 isoform X1. (1207 aa)
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
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