STRINGSTRING
PDE6C PDE6C GNB1 GNB1 GNGT2 GNGT2 NLK NLK PDE6B PDE6B WNT11 WNT11 GNB5 GNB5 PLCB2 PLCB2 LEF1 LEF1 TCF7L1 TCF7L1 GNG4 GNG4 PDE6G PDE6G FZD3 FZD3 MAP3K20 MAP3K20 PPP3CC PPP3CC GNG13 GNG13 GNG7 GNG7 NFATC1 NFATC1 LOC102368918 LOC102368918 PLCB3 PLCB3 TCF7 TCF7 GNB4 GNB4 MAP3K7 MAP3K7 PPP3R1 PPP3R1 TCF7L2 TCF7L2 PLCB1 PLCB1 PDE6H PDE6H GNG2 GNG2 LOC102385776 LOC102385776 NFAT5 NFAT5 FZD6 FZD6 GNG5 GNG5 FZD4 FZD4 GNG12 GNG12 CTNNB1 CTNNB1 LOC102372061 LOC102372061 WDR92 WDR92
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDE6CPhosphodiesterase. (840 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (525 aa)
PDE6BPhosphodiesterase. (834 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5 isoform X1. (353 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1207 aa)
LEF1Lymphoid enhancer-binding factor 1. (349 aa)
TCF7L1Transcription factor 7-like 1. (454 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
PDE6GRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma. (90 aa)
FZD3LOW QUALITY PROTEIN: frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (670 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20 isoform X3. (807 aa)
PPP3CCSerine/threonine-protein phosphatase. (438 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
NFATC1Nuclear factor of activated T-cells, cytoplasmic 1. (636 aa)
LOC102368918Nuclear factor of activated T-cells, cytoplasmic 1-like isoform X1. (301 aa)
PLCB3Phosphoinositide phospholipase C. (795 aa)
TCF7Transcription factor 7 isoform X1. (482 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7 isoform X1. (571 aa)
PPP3R1Calcineurin subunit B type 1. (160 aa)
TCF7L2Transcription factor 7-like 2 isoform X1. (584 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa)
PDE6HRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma. (85 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (93 aa)
LOC102385776Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (128 aa)
NFAT5Nuclear factor of activated T-cells 5 isoform X1. (1523 aa)
FZD6Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family. (667 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (43 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (450 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
CTNNB1Catenin beta-1. (784 aa)
LOC102372061Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
WDR92WD repeat-containing protein 92. (359 aa)
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
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