81 items (Alligator sinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TRIO	Triple functional domain protein isoform X1. (3051 aa)
	ADRA1D	alpha-1D adrenergic receptor. (507 aa)
	RHOC	Rho-related GTP-binding protein RhoC isoform X2. (231 aa)
	ARHGEF11	LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 11. (1699 aa)
	ARHGEF2	Rho guanine nucleotide exchange factor 2. (1147 aa)
	GNG4	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
	ARHGEF9	Rho guanine nucleotide exchange factor 9 isoform X1. (575 aa)
	ARHGEF26	Rho guanine nucleotide exchange factor 26 isoform X1. (590 aa)
	LOC102375630	A-kinase anchor protein 13-like. (1317 aa)
	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
	MCF2	LOW QUALITY PROTEIN: proto-oncogene DBL. (1122 aa)
	LOC102383723	Kalirin. (1532 aa)
	AKAP13	A-kinase anchor protein 13. (1419 aa)
	ARHGEF18	LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 18. (1577 aa)
	GNG5	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (43 aa)
	LOC102371144	Uncharacterized protein LOC102371144. (774 aa)
	GNA13	Guanine nucleotide-binding protein subunit alpha-13. (310 aa)
	NGEF	Ephexin-1. (673 aa)
	GNB5	Guanine nucleotide-binding protein subunit beta-5 isoform X1. (353 aa)
	VAV1	Proto-oncogene vav isoform X1. (929 aa)
	TIAM1	T-lymphoma invasion and metastasis-inducing protein 1. (1598 aa)
	ECT2	Protein ECT2 isoform X1. (990 aa)
	ADRA1B	alpha-1B adrenergic receptor. (511 aa)
	ARHGEF17	Rho guanine nucleotide exchange factor 17. (1433 aa)
	GNGT2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
	ARHGEF5	Rho guanine nucleotide exchange factor 5. (1734 aa)
	TBXA2R	Thromboxane A2 receptor. (355 aa)
	FGD4	FYVE, RhoGEF and PH domain-containing protein 4 isoform X1. (921 aa)
	GNA12	Guanine nucleotide-binding protein subunit alpha-12. (305 aa)
	ARHGEF10L	Rho guanine nucleotide exchange factor 10-like protein isoform X1. (1370 aa)
	LOC102372061	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	GNG12	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	RHOA	Transforming protein RhoA. (193 aa)
	ADRA1A	alpha-1A adrenergic receptor. (296 aa)
	ARHGEF39	Rho guanine nucleotide exchange factor 39. (345 aa)
	ARHGEF38	Rho guanine nucleotide exchange factor 38. (785 aa)
	ROCK1	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1377 aa)
	ARHGEF6	Rho guanine nucleotide exchange factor 6 isoform X1. (773 aa)
	ARHGEF3	Rho guanine nucleotide exchange factor 3 isoform X1. (580 aa)
	RHOB	Rho-related GTP-binding protein RhoB. (193 aa)
	NET1	Neuroepithelial cell-transforming gene 1 protein. (541 aa)
	LOC102387884	Protein-glutamine gamma-glutamyltransferase E isoform X1. (694 aa)
	LOC102383248	Transforming protein RhoA-like. (315 aa)
	ARHGEF19	Rho guanine nucleotide exchange factor 19 isoform X1. (875 aa)
	FGD2	FYVE, RhoGEF and PH domain-containing protein 2 isoform X1. (696 aa)
	LOC102381567	alpha-1A adrenergic receptor-like. (235 aa)
	TIAM2	T-lymphoma invasion and metastasis-inducing protein 2 isoform X1. (1724 aa)
	LOC102370145	LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 19-like. (785 aa)
	ARHGEF16	Rho guanine nucleotide exchange factor 16 isoform X1. (706 aa)
	GNG13	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
	ARHGEF33	Rho guanine nucleotide exchange factor 33 isoform X1. (769 aa)
	SESTD1	SEC14 domain and spectrin repeat-containing protein 1. (696 aa)
	LOC102388295	Protein-glutamine gamma-glutamyltransferase 6. (697 aa)
	MCF2L	Guanine nucleotide exchange factor DBS isoform X1. (1194 aa)
	GNG7	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	ARHGEF40	Rho guanine nucleotide exchange factor 40 isoform X1. (1595 aa)
	ARHGEF25	Rho guanine nucleotide exchange factor 25. (451 aa)
	LOC102388479	glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-A-like. (339 aa)
	LOC112548131	LOW QUALITY PROTEIN: glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-A-like. (340 aa)
	ARHGEF1	LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 1. (997 aa)
	ARHGEF7	Rho guanine nucleotide exchange factor 7 isoform X1. (745 aa)
	VAV2	Guanine nucleotide exchange factor VAV2. (755 aa)
	LOC102377708	Kalirin isoform X1. (1287 aa)
	LOC112549268	Kalirin-like. (100 aa)
	FGD3	FYVE, RhoGEF and PH domain-containing protein 3 isoform X1. (908 aa)
	MCF2L2	Probable guanine nucleotide exchange factor MCF2L2. (1145 aa)
	GNB4	Guanine nucleotide-binding protein subunit beta-4. (340 aa)
	LOC106721907	Uncharacterized protein LOC106721907. (376 aa)
	ARHGEF37	Rho guanine nucleotide exchange factor 37 isoform X3. (752 aa)
	ARHGEF12	Rho guanine nucleotide exchange factor 12 isoform X1. (1461 aa)
	ECT2L	Epithelial cell-transforming sequence 2 oncogene-like. (950 aa)
	ROCK2	Rho-associated protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1455 aa)
	SOS2	LOW QUALITY PROTEIN: son of sevenless homolog 2. (1285 aa)
	GNG2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (93 aa)
	SOS1	Son of sevenless homolog 1 isoform X1. (1288 aa)
	ITSN1	Intersectin-1 isoform X3. (1714 aa)
	VAV3	Guanine nucleotide exchange factor VAV3. (838 aa)
	ARHGEF10	Rho guanine nucleotide exchange factor 10 isoform X1. (1363 aa)
	LOC112550852	Nascent polypeptide-associated complex subunit alpha, muscle-specific form-like. (961 aa)
	LOC102385776	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (128 aa)
	ARHGEF4	Rho guanine nucleotide exchange factor 4 isoform X1. (2311 aa)

Your Current Organism:

Alligator sinensis

NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADRA1A	ARHGEF12	A0A1U7SB85	A0A3Q0GBL1	alpha-1A adrenergic receptor.	Rho guanine nucleotide exchange factor 12 isoform X1.	0.418
ADRA1A	GNA12	A0A1U7SB85	A0A1U7S3J0	alpha-1A adrenergic receptor.	Guanine nucleotide-binding protein subunit alpha-12.	0.952
ADRA1A	GNA13	A0A1U7SB85	A0A1U7R4Y1	alpha-1A adrenergic receptor.	Guanine nucleotide-binding protein subunit alpha-13.	0.952
ADRA1A	GNB1	A0A1U7SB85	A0A3Q0HAC8	alpha-1A adrenergic receptor.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.583
ADRA1A	GNB4	A0A1U7SB85	A0A3Q0G149	alpha-1A adrenergic receptor.	Guanine nucleotide-binding protein subunit beta-4.	0.583
ADRA1A	GNG13	A0A1U7SB85	A0A1U8DEI1	alpha-1A adrenergic receptor.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13.	0.490
ADRA1A	GNG2	A0A1U7SB85	A0A3Q0GM28	alpha-1A adrenergic receptor.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.491
ADRA1A	GNG4	A0A1U7SB85	A0A3Q0HGF5	alpha-1A adrenergic receptor.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.491
ADRA1A	GNG5	A0A1U7SB85	A0A3Q0H5H4	alpha-1A adrenergic receptor.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.492
ADRA1A	GNGT2	A0A1U7SB85	A0A1U7RST2	alpha-1A adrenergic receptor.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.503
ADRA1A	LOC102372061	A0A1U7SB85	A0A1U7S7Y9	alpha-1A adrenergic receptor.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.456
ADRA1A	LOC102385776	A0A1U7SB85	A0A3Q0GYD3	alpha-1A adrenergic receptor.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.490
ADRA1B	GNA12	A0A1U7RN68	A0A1U7S3J0	alpha-1B adrenergic receptor.	Guanine nucleotide-binding protein subunit alpha-12.	0.948
ADRA1B	GNA13	A0A1U7RN68	A0A1U7R4Y1	alpha-1B adrenergic receptor.	Guanine nucleotide-binding protein subunit alpha-13.	0.948
ADRA1B	GNB1	A0A1U7RN68	A0A3Q0HAC8	alpha-1B adrenergic receptor.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.585
ADRA1B	GNB4	A0A1U7RN68	A0A3Q0G149	alpha-1B adrenergic receptor.	Guanine nucleotide-binding protein subunit beta-4.	0.585
ADRA1B	GNG13	A0A1U7RN68	A0A1U8DEI1	alpha-1B adrenergic receptor.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13.	0.493
ADRA1B	GNG2	A0A1U7RN68	A0A3Q0GM28	alpha-1B adrenergic receptor.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.491
ADRA1B	GNG4	A0A1U7RN68	A0A3Q0HGF5	alpha-1B adrenergic receptor.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.491
ADRA1B	GNG5	A0A1U7RN68	A0A3Q0H5H4	alpha-1B adrenergic receptor.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.503