58 items (Alligator sinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GNB4	Guanine nucleotide-binding protein subunit beta-4. (340 aa)
	LOC102380382	long-chain-fatty-acid--CoA ligase 3. (259 aa)
	GNA15	Guanine nucleotide-binding protein subunit alpha-15 isoform X1. (396 aa)
	PLCB3	Phosphoinositide phospholipase C. (795 aa)
	CACNA1S	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1898 aa)
	FFAR1	Free fatty acid receptor 1. (565 aa)
	RAPGEF4	Rap guanine nucleotide exchange factor 4. (1004 aa)
	LOC102387635	Adenylate cyclase type 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (819 aa)
	GNG7	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	LOC102383727	LOW QUALITY PROTEIN: inositol 1,4,5-trisphosphate receptor type 2-like. (1297 aa)
	RAPGEF3	Rap guanine nucleotide exchange factor 3. (864 aa)
	GNG13	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
	LOC102379727	Inositol 1,4,5-trisphosphate receptor type 2. (1420 aa)
	SNX19	Sorting nexin-19 isoform X1. (1003 aa)
	LOC102380144	long-chain-fatty-acid--CoA ligase 3-like. (453 aa)
	ACSL4	long-chain-fatty-acid--CoA ligase 4 isoform X1. (711 aa)
	PRKACA	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (401 aa)
	ADCY6	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1242 aa)
	LOC102386960	Guanine nucleotide-binding protein subunit alpha-14. (237 aa)
	THAP1	THAP domain-containing protein 1. (235 aa)
	FAP	Prolyl endopeptidase FAP; Belongs to the peptidase S9B family. (757 aa)
	GNG12	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	KCNG2	Potassium voltage-gated channel subfamily G member 2; Belongs to the potassium channel family. (521 aa)
	LOC102372061	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	LOC102388376	Guanine nucleotide-binding protein G(Q) subunit alpha isoform X1. (333 aa)
	ADRA2C	alpha-2C adrenergic receptor. (419 aa)
	KCNJ11	ATP-sensitive inward rectifier potassium channel 11. (394 aa)
	ABCC8	ATP-binding cassette sub-family C member 8. (1587 aa)
	CD36	Platelet glycoprotein 4; Belongs to the CD36 family. (470 aa)
	SLC2A2	Solute carrier family 2, facilitated glucose transporter member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (524 aa)
	GNGT2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
	GNA11	Guanine nucleotide-binding protein subunit alpha-11 isoform X1. (357 aa)
	GNB5	Guanine nucleotide-binding protein subunit beta-5 isoform X1. (353 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1207 aa)
	KCNB1	Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (864 aa)
	PRKACB	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (401 aa)
	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
	CACNA1F	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1915 aa)
	GNG4	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
	GCG	Glucagon precursor. (206 aa)
	LOC102385116	Voltage-dependent calcium channel subunit alpha-2/delta-1-like isoform X1. (225 aa)
	RAPGEF5	Rap guanine nucleotide exchange factor 5 isoform X1. (813 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2721 aa)
	LOC102385776	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (128 aa)
	THAP7	THAP domain-containing protein 7. (360 aa)
	CACNA1D	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2105 aa)
	CACNA1C	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2175 aa)
	RAPGEFL1	Rap guanine nucleotide exchange factor-like 1. (570 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa)
	GLP1R	LOW QUALITY PROTEIN: glucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (445 aa)
	ADRA2A	alpha-2A adrenergic receptor. (376 aa)
	CACNA2D2	Voltage-dependent calcium channel subunit alpha-2/delta-2. (1124 aa)
	CACNA2D1	Voltage-dependent calcium channel subunit alpha-2/delta-1. (863 aa)
	GNG2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (93 aa)
	ITPR3	LOW QUALITY PROTEIN: inositol 1,4,5-trisphosphate receptor type 3. (2748 aa)
	KCNS3	LOW QUALITY PROTEIN: potassium voltage-gated channel subfamily S member 3; Belongs to the potassium channel family. (531 aa)
	GNG5	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (43 aa)
	LOC102383230	Adenylate cyclase type 5-like. (219 aa)

Your Current Organism:

Alligator sinensis

NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCC8	KCNJ11	A0A1U7S3H9	A0A1U7S5Z1	ATP-binding cassette sub-family C member 8.	ATP-sensitive inward rectifier potassium channel 11.	0.998
ABCC8	PRKACA	A0A1U7S3H9	A0A1U7SIV0	ATP-binding cassette sub-family C member 8.	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily.	0.552
ABCC8	PRKACB	A0A1U7S3H9	A0A3Q0HA50	ATP-binding cassette sub-family C member 8.	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily.	0.552
ABCC8	RAPGEF3	A0A1U7S3H9	A0A1U8DL24	ATP-binding cassette sub-family C member 8.	Rap guanine nucleotide exchange factor 3.	0.663
ABCC8	RAPGEF4	A0A1U7S3H9	A0A3Q0FIE0	ATP-binding cassette sub-family C member 8.	Rap guanine nucleotide exchange factor 4.	0.835
ABCC8	SLC2A2	A0A1U7S3H9	A0A1U7RZH7	ATP-binding cassette sub-family C member 8.	Solute carrier family 2, facilitated glucose transporter member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.439
ACSL4	LOC102380144	A0A1U7SKR1	A0A1U7SMQ0	long-chain-fatty-acid--CoA ligase 4 isoform X1.	long-chain-fatty-acid--CoA ligase 3-like.	0.637
ADCY6	GNB1	A0A1U7SHY1	A0A3Q0HAC8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.775
ADCY6	GNB4	A0A1U7SHY1	A0A3Q0G149	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit beta-4.	0.775
ADCY6	GNB5	A0A1U7SHY1	A0A1U7RDG9	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit beta-5 isoform X1.	0.733
ADCY6	GNG12	A0A1U7SHY1	A0A1U7S8Y2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.771
ADCY6	GNG13	A0A1U7SHY1	A0A1U8DEI1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13.	0.798
ADCY6	GNG2	A0A1U7SHY1	A0A3Q0GM28	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.770
ADCY6	GNG4	A0A1U7SHY1	A0A3Q0HGF5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.770
ADCY6	GNG5	A0A1U7SHY1	A0A3Q0H5H4	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.795
ADCY6	GNG7	A0A1U7SHY1	A0A1U8DQM5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.777
ADCY6	GNGT2	A0A1U7SHY1	A0A1U7RST2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.792
ADCY6	LOC102372061	A0A1U7SHY1	A0A1U7S7Y9	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.783
ADCY6	LOC102385776	A0A1U7SHY1	A0A3Q0GYD3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.796
ADCY6	PRKACA	A0A1U7SHY1	A0A1U7SIV0	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily.	0.868